Primary Site >> Colorectal Cancer
Gene >> MMP9
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Ref: Actin cytoskeletal organization loss in the benign-to-malignant tumor transition in cultured human colonic epithelial cells. PMID: 6722823 |
Ref: Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. PMID: 2174463 |
Ref: M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer. PMID: 8416738 |
Ref: Distribution of gelatinase B (MMP-9) and type IV collagen in colorectal carcinoma. PMID: 7814988 Ref: Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. PMID: 7992833 Ref: Autocrine factor enhancing the secretion of M(r) 95,000 gelatinase (matrix metalloproteinase 9) in serum-free medium conditioned with murine metastatic colon carcinoma cells. PMID: 8012988 |
Ref: [Significance of MMP-9 and TIMP-1 production during liver metastasis in colorectal cancer]. PMID: 7630024 Ref: Distinct pattern of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 mRNA expression in human colorectal cancer and liver metastases. PMID: 7669564 Ref: Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties. PMID: 7896811 |
Ref: Metastatic colorectal cancer cells induce matrix metalloproteinase release by human monocytes. PMID: 8521614 Ref: 92 kDa type IV collagenase (MMP-9) is expressed in neutrophils and macrophages but not in malignant epithelial cells in human colon cancer. PMID: 8543396 Ref: Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. PMID: 8548762 Ref: Establishment and characterization of high- and low-lung-metastatic cell lines derived from murine colon adenocarcinoma 26 tumor line. PMID: 8609053 Ref: Correspondence re: N-B. Liabakk et al., matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res., 56: 190-196, 1966. PMID: 8758934 Ref: Involvement of transforming growth factor beta1 in autocrine enhancement of gelatinase B secretion by murine metastatic colon carcinoma cells. PMID: 8764135 Ref: Colocalisation of matrix metalloproteinase-9-mRNA and protein in human colorectal cancer stromal cells. PMID: 8883399 Ref: Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors. PMID: 8895669 Ref: Prediction of colorectal cancer relapse and survival via tissue RNA levels of matrix metalloproteinase-9. PMID: 8955659 |
Ref: Stromal expression of MMP-9 and urokinase receptor is inversely associated with liver metastasis and with infiltrating growth in human colorectal cancer: a novel approach from immune/inflammatory aspect. PMID: 9045899 Ref: Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor. PMID: 9062395 Ref: Detection of matrix metalloproteinase activity in human pancreatic cancer. PMID: 9086544 Ref: Characterizing human colorectal carcinomas by proteolytic profile. PMID: 9239513 Ref: [Significance in gene expression of matrix metalloproteinase-9, urokinase-type plasminogen activator and tissue inhibitor of metalloproteinase for metastases of gastric and/or colo-rectal cancer]. PMID: 9263524 Ref: Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage. PMID: 9310250 Ref: [Effect on 5'-deoxy-5-fluorouridine (5'-DFUR) of pyrimidine nucleoside phosphorylase (PyNPase), matrix metalloprotease and serum IAP values. Hokuriku Colorectal Cancer Chemotherapy Study Group]. PMID: 9350241 Ref: Inhibitory effects of oleic and docosahexaenoic acids on lung metastasis by colon-carcinoma-26 cells are associated with reduced matrix metalloproteinase-2 and -9 activities. PMID: 9389579 Ref: Gelatinase B (MMP-9) expression and survival in colorectal cancer patients. PMID: 9457528 Ref: Increased type IV collagen-degrading activity in metastases originating from primary tumors of the human colon. PMID: 9702942 Ref: Expression and localization of matrix metalloproteinases and tissue inhibitors of metalloproteinases as a prognostic factor in advanced colorectal carcinomas. PMID: 21590124 |
Ref: Stromal reaction in cancer tissue: pathophysiologic significance of the expression of matrix-degrading enzymes in relation to matrix turnover and immune/inflammatory reactions. PMID: 9589457 Ref: Short chain fatty acids inhibit human (SW1116) colon cancer cell invasion by reducing urokinase plasminogen activator activity and stimulating TIMP-1 and TIMP-2 activities, rather than via MMP modulation. PMID: 9695737 Ref: Unique activation of matrix metalloproteinase-9 within human liver metastasis from colorectal cancer. PMID: 9703281 Ref: In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma. PMID: 9721885 Ref: [Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]. PMID: 9742524 Ref: Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy. PMID: 9836483 |
Ref: Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer. PMID: 10223763 Ref: Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis. PMID: 10334190 Ref: Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma. PMID: 10485622 Ref: Proteolysis in human breast and colorectal cancer. PMID: 10496354 Ref: Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo. PMID: 10545021 Ref: Proteolysis in colorectal cancer. PMID: 10621835 Ref: Involvement of TNF-alpha in enhancement of invasion and metastasis of colon 26-L5 carcinoma cells in mice by social isolation stress. PMID: 10850887 |
Ref: Clinicopathologic significance of urokinase receptor- and MMP-9-positive stromal cells in human colorectal cancer: functional multiplicity of matrix degradation on hematogenous metastasis. PMID: 10728590 Ref: Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer. PMID: 10732772 Ref: Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer. PMID: 10810401 Ref: Circulating Levels of Matrix Metalloproteinase-9 in Patients with Colorectal Cancer. PMID: 10912671 Ref: A functional proteomics screen of proteases in colorectal carcinoma. PMID: 10952024 Ref: Plasma metalloproteinase activity is enhanced in the euglobulin fraction of breast and lung cancer patients. PMID: 10956415 Ref: Matrix metalloproteinases, their tissue inhibitors and colorectal cancer staging. PMID: 10971431 Ref: Significance of coexpression of urokinase-type plasminogen activator, and matrix metalloproteinase 3 (stromelysin) and 9 (gelatinase B) in colorectal carcinoma. PMID: 11027463 Ref: Social isolation stress augments angiogenesis induced by colon 26-L5 carcinoma cells in mice. PMID: 11206831 Ref: Prognostic significance of matrix metalloproteinase expression in colorectal carcinomas. PMID: 11212843 Ref: Plasma TIMP-1-a marker of metastasis in colorectal cancer. PMID: 23577994 |
Ref: Inhibition of tumor cell invasiveness by chemically modified tetracyclines. PMID: 11172681 Ref: AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice. PMID: 11268284 Ref: Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. PMID: 11280787 Ref: The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer. PMID: 11332689 Ref: nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression. PMID: 11337376 Ref: The epidermal growth factor receptor as a target for cancer therapy. PMID: 11350723 Ref: Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase. PMID: 11401321 Ref: Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha. PMID: 11420751 Ref: Imbalance between matrix metalloproteinase 9 and tissue inhibitor of metalloproteinases 1 expression by tumor cells implicated in liver metastasis from colorectal carcinoma. PMID: 11680936 Ref: Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis. PMID: 11691582 Ref: Activity and cellular origin of gelatinases in patients with colon and rectal carcinoma differential activity of matrix metalloproteinase-9. PMID: 11745204 Ref: Interleukin-15 expression is associated with malignant potential in colon cancer cells. PMID: 11752902 Ref: Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells. PMID: 11781819 Ref: [Effect of lidamycin on the expression of genes involved in invasion regulation in HCT-8 human colon cancer cells]. PMID: 12580049 Ref: Genetic modification of cell lines to enhance their metastatic capability. PMID: 21340844 |
Ref: Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166. PMID: 11734335 Ref: Measuring gelatinase activity in colorectal cancer. PMID: 11869009 Ref: Gene expression profiling in silico: relative expression of candidate angiogenesis associated genes in renal cell carcinomas. PMID: 11937758 Ref: Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer. PMID: 12085179 Ref: Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas. PMID: 12173379 Ref: Integrin alpha(v)beta6-associated ERK2 mediates MMP-9 secretion in colon cancer cells. PMID: 12177807 Ref: Bombesin stimulates invasion and migration of Isreco1 colon carcinoma cells in a Rho-dependent manner. PMID: 12183443 |
Ref: Differential effects between amphoterin and advanced glycation end products on colon cancer cells. PMID: 12640679 Ref: In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin. PMID: 12754293 Ref: Increased surgical stress promotes tumor metastasis. PMID: 12773983 Ref: Overexpression of the thrombospondin 2 (TSP2) gene modulated by the matrix metalloproteinase family expression and production in human colon carcinoma cell line. PMID: 12792739 Ref: Determining the levels of matrix metalloproteinase-9 in portal and peripheral blood is useful for predicting liver metastasis of colorectal cancer. PMID: 12810833 Ref: Profiles of matrix metalloproteinases and their tissue inhibitors in intraperitoneal drainage fluid: relationship to wound healing. PMID: 12846914 Ref: Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients. PMID: 14520690 Ref: Evaluation of urinary plasminogen activator, its receptor, matrix metalloproteinase-9, and von Willebrand factor in pancreatic cancer. PMID: 14581368 Ref: Detection of type IV collagenase activity in malignant ascites. PMID: 14606104 Ref: Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis. PMID: 14648736 |
Ref: Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. PMID: 14760389 Ref: Circulating matrix metalloproteinase-9 is transiently elevated after colorectal surgery. PMID: 14986032 Ref: Role of matrix metalloproteinases (MMPs) in colorectal cancer. PMID: 15000152 Ref: A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer. PMID: 15041713 Ref: Doxycycline inhibits cell proliferation and invasive potential: combination therapy with cyclooxygenase-2 inhibitor in human colorectal cancer cells. PMID: 15085079 Ref: Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel. PMID: 15185339 Ref: The membrane-anchored matrix metalloproteinase (MMP) regulator RECK in combination with MMP-9 serves as an informative prognostic indicator for colorectal cancer. PMID: 15328199 Ref: Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. PMID: 15387371 Ref: Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis. PMID: 15390257 Ref: The role of gelatinases in colorectal cancer progression and metastasis. PMID: 15588763 Ref: Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers. PMID: 15623598 Ref: Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers. PMID: 15623631 Ref: Advanced colorectal carcinomas measuring 20 mm or less exhibit markedly higher invasiveness despite their size. PMID: 15628723 |
Ref: Clinical relevance of MMP-9, MMP-2, TIMP-1 and TIMP-2 in colorectal cancer. PMID: 15583811 Ref: Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer. PMID: 15592677 Ref: In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human colon cancer cell HCT 116 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry. PMID: 15706410 Ref: Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells. PMID: 15756690 Ref: (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells. PMID: 15860507 Ref: Impairment of stromelysin-1 transcriptional activity by promoter mutations in high microsatellite instability colorectal tumors. PMID: 15867378 Ref: Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells. PMID: 15868913 Ref: Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases. PMID: 15869913 Ref: Establishment and characterization of 7 new monoclonal antibodies to tissue inhibitor of metalloproteinases-1. PMID: 15870512 Ref: [Role of tissue factor in the invasion of cultured human colon carcinoma cells and its correlation with matrix metalloproteinases]. PMID: 15968316 Ref: Inhibition of experimental colon cancer metastasis by the GABA-receptor agonist nembutal. PMID: 15970706 Ref: [The expression of matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinases (TIMPs) and angiogenesis in relation to the depth of tumor invasion and lymph node metastasis in submucosally invasive colorectal carcinoma]. PMID: 15973074 Ref: Effects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cells in vitro. PMID: 15991286 Ref: Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells. PMID: 16001424 Ref: A mechanistic study of colon cancer growth promoted by cigarette smoke extract. PMID: 16125168 Ref: CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. PMID: 16125170 Ref: [Correlation between the activation of AP-1 signal transduction pathway and metastasis of colorectal carcinoma]. PMID: 16167262 Ref: Dentin matrix protein 1 enhances invasion potential of colon cancer cells by bridging matrix metalloproteinase-9 to integrins and CD44. PMID: 16357164 Ref: Expressions of matrix metalloproteinase-7 and -9 and their prognostic significances in rectal cancer. PMID: 19956372 |
Ref: Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer. PMID: 16046057 Ref: Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy. PMID: 16114015 Ref: The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. PMID: 16133529 Ref: Etodolac, a selective cyclooxygenase-2 inhibitor, inhibits liver metastasis of colorectal cancer cells via the suppression of MMP-9 activity. PMID: 16391837 Ref: Altered plasma matrix metalloproteinase-9/tissue inhibitor of matrix [corrected] metalloproteinase-1 concentration during the early postoperative period in patients with colorectal cancer. PMID: 16432654 Ref: [The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]. PMID: 16456793 Ref: Gefitinib decreases the synthesis of matrix metalloproteinase and the adhesion to extracellular matrix proteins of colon cancer cells. PMID: 16475688 Ref: Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer. PMID: 16551873 Ref: Gastrin enhances the angiogenic potential of endothelial cells via modulation of heparin-binding epidermal-like growth factor. PMID: 16585174 Ref: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. PMID: 16619535 Ref: MMP-9 and cathepsin B expression in tumor budding as an indicator of a more aggressive phenotype of colorectal cancer (CRC). PMID: 16619576 Ref: MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases. PMID: 16687484 Ref: Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. PMID: 16691544 Ref: [Modulation of colon cancer cell invasiveness induced by deoxycholic acid]. PMID: 16861876 Ref: Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer. PMID: 16916471 Ref: Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation. PMID: 16934296 Ref: Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence. PMID: 16973348 Ref: Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. PMID: 17047044 Ref: A prospective study to assess the value of MMP-9 in improving the appropriateness of urgent referrals for colorectal cancer. PMID: 17059590 Ref: Suppression effects of human recombinant tissue inhibitor of metalloproteinases-1(TIMP-1) on tumor proliferation using in vivo treatment model of well-differentiated colon cancer cell line, HT29. PMID: 17072372 Ref: Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential? PMID: 17075343 Ref: Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population. PMID: 17076885 Ref: Effect of DPC4 gene on invasion and metastasis of colorectal carcinoma cells. PMID: 17151782 Ref: Clinicopathological study of the colorectal mucinous carcinomas. PMID: 17256436 |
Ref: Matrix metalloproteinase-9,-3 and tissue inhibitor of matrix metalloproteinase-1 in colorectal cancer: relationship to clinicopathological variables. PMID: 16615041 Ref: Matrix metalloproteinase-9 expression correlated with tumor response in patients with locally advanced rectal cancer undergoing preoperative chemoradiotherapy. PMID: 17071013 Ref: Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation. PMID: 17109104 Ref: Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells. PMID: 17186550 Ref: Influence of different strategies of volume replacement on the activity of matrix metalloproteinases: an in vitro and in vivo study. PMID: 17197849 Ref: Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo. PMID: 17224907 Ref: MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells. PMID: 17332939 Ref: Effects of two conventional preoperative radiation schedules on anastomotic healing in the rat colon. PMID: 17337891 Ref: Beneficial influence of microsatellite instability on gelatinase-tissue inhibitors of metalloproteinase balance in colorectal cancer. PMID: 17348445 Ref: Warm hepatic ischemia-reperfusion promotes growth of colorectal carcinoma micrometastases in mouse liver via matrix metalloproteinase-9 induction. PMID: 17363593 Ref: Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo. PMID: 17368880 Ref: SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. PMID: 17369830 Ref: Genomic and transcriptomic prognostic factors in R0 Dukes B and C colorectal cancer patients. PMID: 17390011 Ref: CXCL10 promotes invasion-related properties in human colorectal carcinoma cells. PMID: 17409450 Ref: Resident stromal cell-derived MMP-9 promotes the growth of colorectal metastases in the liver microenvironment. PMID: 17417772 Ref: Suppression of matrix metalloproteinase-9 by 4-methylumbelliferone. PMID: 17470403 Ref: Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels. PMID: 17516864 Ref: Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese. PMID: 17546628 Ref: Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. PMID: 17608852 Ref: A novel in vitro model of lymphatic metastasis from colorectal cancer. PMID: 17640671 Ref: [Short hairpin RNA-mediated survivin gene silencing inhibits invasion and metastasis of human colon carcinoma cell line SW480 in vitro]. PMID: 17666323 Ref: Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer. PMID: 17669467 Ref: Matrix metalloproteinase-9-1562C>T polymorphism may increase the risk of lymphatic metastasis of colorectal cancer. PMID: 17729419 Ref: Inhibitory effects of retinoic acid and IIF on growth, migration and invasiveness in the U87MG human glioblastoma cell line. PMID: 17786368 Ref: Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients. PMID: 17912241 Ref: Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion. PMID: 17982677 Ref: The value and correlation between PRL-3 expression and matrix metalloproteinase activity and expression in human gliomas. PMID: 18021371 Ref: Prognostic significance of expression of matrix metalloproteinase in colorectal adenocarcinomas and their metastases. PMID: 18214299 Ref: Induction of Proteases in Peritoneal Carcinomatosis, the Role of ICAM-1/CD43 Interaction. PMID: 19662219 |
Ref: Functional proteomics study reveals that N-Acetylglucosaminyltransferase V reinforces the invasive/metastatic potential of colon cancer through aberrant glycosylation on tissue inhibitor of metalloproteinase-1. PMID: 17878270 Ref: Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells. PMID: 18084005 Ref: Integrin alpha v beta 6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver. PMID: 18294287 Ref: Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis. PMID: 18326560 Ref: Matrix metalloproteinase-9 expression in the normal mucosa-adenoma-dysplasia-adenocarcinoma sequence of the colon. PMID: 18347934 Ref: Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy. PMID: 18376229 Ref: Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products. PMID: 18381954 Ref: Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro. PMID: 18416455 Ref: Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from co PMID: 18425389 Ref: [Role of vascular endothelial growth factor receptor 1-positive hematopoietic progenitor cell clusters in human colorectal carcinoma metastasis]. PMID: 18504182 Ref: MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not. PMID: 18506186 Ref: Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts. PMID: 18508606 Ref: Clinicopathological analysis of invading muscularis propria (T2) cancers < or =20 mm in diameter. PMID: 18543547 Ref: Is serum matrix metalloproteinase 9 a useful biomarker in detection of colorectal cancer? Considering pre-analytical interference that may influence diagnostic accuracy. PMID: 18648367 Ref: Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1 alpha expression in colon carcinoma cells. PMID: 18674879 Ref: VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis. PMID: 18691882 Ref: [Expression of MMP-2, MMP-9 and collagen type IV and their relationship in colorectal carcinomas]. PMID: 18782525 Ref: Resistin in human colorectal cancer: increased expression independently of resistin promoter -420C > G genotype. PMID: 18798067 Ref: [Effects of phosphatase of regenerating liver cell-3 gene silence by RNA interference on the expression of matrix metalloproteinases-2,-9 in human colon cancer cells]. PMID: 18803055 Ref: Soluble transforming growth factor beta type II receptor attenuates TGF-beta1 activity in human colorectal cancer LoVo cells. PMID: 19020727 Ref: Clinical significance of levels of molecular biological markers in zones of invasive front-line of colorectal cancer. PMID: 19526105 Ref: Overexpression of matrix metalloproteinase 9 in tumor epithelial cells correlates with colorectal cancer metastasis. PMID: 20443834 Ref: The tumorigenic, invasive and metastatic potential of epithelial and round subpopulations of the SW480 human colon cancer cell line. PMID: 21479483 |
Ref: Upregulation of activator protein-4 in human colorectal cancer with metastasis. PMID: 18480385 Ref: Macrophage migration inhibitory factor promotes colorectal cancer. PMID: 19009023 Ref: Resistance to EGF-R (erbB-1) and VEGF-R modulating agents. PMID: 19124237 Ref: Impact of p27mt gene on transplantation model of human colorectal cancer in nude mice. PMID: 19140239 Ref: Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme. PMID: 19175925 Ref: Synthesis and evaluation of myxochelin analogues as antimetastatic agents. PMID: 19282185 Ref: NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells. PMID: 19308044 Ref: Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9. PMID: 19336567 Ref: Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer. PMID: 19359472 Ref: Clinical significance of Neutrophil gelatinase-associated lipocalin(NGAL) expression in primary rectal cancer. PMID: 19419554 Ref: Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expression. PMID: 19426720 Ref: Poly(ADP-ribose) polymerase inhibition down-regulates expression of metastasis-related genes in CT26 colon carcinoma cells. PMID: 19468250 Ref: Tumor endothelium is characterized by a matrix remodeling signature. PMID: 19482697 Ref: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. PMID: 19501039 Ref: Key enzymes of the extracellular matrix in colorectal cancer. PMID: 19529860 Ref: [Galectin-9 isoforms influence the adhesion between colon carcinoma LoVo cells and human umbilical vein endothelial cells in vitro by regulating the expression of E-selectin in LoVo cells]. PMID: 19538882 Ref: Active MMP-2 effectively identifies the presence of colorectal cancer. PMID: 19551856 Ref: Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness. PMID: 19603013 Ref: A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells. PMID: 19616522 Ref: Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. PMID: 19623659 Ref: [Role of CCL21/CCR7 in invasion of colorectal carcinoma cell line SW480]. PMID: 19624896 Ref: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. PMID: 19722233 Ref: Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells. PMID: 19820721 Ref: Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo. PMID: 19885606 Ref: NF-kappaB signaling pathway, inflammation and colorectal cancer. PMID: 19887045 Ref: Prognostic significance of matrix metalloproteinase-9 (MMP-9) in stage II colorectal carcinoma. PMID: 19921474 Ref: Clinicopathological analysis of colorectal cancers in the elderly. PMID: 20187509 |
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Ref: A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4. PMID: 24469032 Ref: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling. PMID: 24497447 Ref: Targeting colon cancer cell NF-kappaB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis. PMID: 24704833 Ref: Gene expression differences in primary colorectal tumors and matched liver metastases: chemotherapy related or tumoral heterogeneity? PMID: 25301403 Ref: Paris saponin VII inhibits metastasis by modulating matrix metalloproteinases in colorectal cancer cells. PMID: 25333739 Ref: PINCH-2 presents functional copy number variation and suppresses migration of colon cancer cells by paracrine activity. PMID: 25346044 Ref: A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. PMID: 25351103 Ref: Long non-coding RNA HOTAIR is associated with human cervical cancer progression. PMID: 25405331 Ref: Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity in osteosarcoma cells. PMID: 25427639 Ref: MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway. PMID: 25431257 Ref: Effects of ephrinB2 gene siRNA on the biological behavior of human colorectal cancer cells. PMID: 25434750 Ref: Prognostic and diagnostic implications of MMP-2, MMP-9, and VEGF-alpha expressions in colorectal cancer. PMID: 25446246 Ref: Bile acid induces MUC2 expression and inhibits tumor invasion in gastric carcinomas. PMID: 25475007 Ref: High-mobility group box 1: a novel inducer of the epithelial-mesenchymal transition in colorectal carcinoma. PMID: 25511739 Ref: The matrix metalloproteinase-7 and pro-enzyme of metalloproteinase-1 as a potential marker for patients with rectal cancer without distant metastasis. PMID: 25549795 Ref: MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer. PMID: 25607234 Ref: Cucurbitacin I inhibits cell migration and invasion and enhances chemosensitivity in colon cancer. PMID: 25625299 Ref: Impact of high glucose on metastasis of colon cancer cells. PMID: 25717237 Ref: Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer. PMID: 25737434 Ref: Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition. PMID: 25750173 Ref: Fentanyl inhibits proliferation and invasion of colorectal cancer via beta-catenin. PMID: 25755709 Ref: Anticancer effect of salidroside on colon cancer through inhibiting JAK2/STAT3 signaling pathway. PMID: 25755753 Ref: miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway. PMID: 25760926 Ref: A therapeutically relevant, 3,3'-diindolylmethane derivative NGD16 attenuates angiogenesis by targeting glucose regulated protein, 78kDa (GRP78). PMID: 25794856 Ref: Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses. PMID: 25834404 Ref: Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer. PMID: 25884903 Ref: Russian study of morphological prognostic factors characterization in BRAF-mutant cutaneous melanoma. PMID: 25888143 Ref: Ubiquitin-specific peptidase 22 inhibits colon cancer cell invasion by suppressing the signal transducer and activator of transcription 3/matrix metalloproteinase 9 pathway. PMID: 25902005 Ref: Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene. PMID: 25914533 Ref: High expression of protein phosphatase 4 is associated with the aggressive malignant behavior of colorectal carcinoma. PMID: 25927939 Ref: [Co-inhibition effect of 17-DMAG and oxaliplatin on proliferation and invasion of colorectal cancer cells]. PMID: 25940182 Ref: Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway. PMID: 25954974 Ref: Downregulation of the CXCR4/CXCL12 axis blocks the activation of the Wnt/beta-catenin pathway in human colon cancer cells. PMID: 25960214 Ref: Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer. PMID: 25961845 Ref: FOXM1-mediated downregulation of uPA and MMP9 by 3,3'-diindolylmethane inhibits migration and invasion of human colorectal cancer cells. PMID: 25962429 Ref: Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice. PMID: 25976379 Ref: Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour. PMID: 26043921 Ref: CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro. PMID: 26045788 Ref: MYBL2 is an independent prognostic marker that has tumor-promoting functions in colorectal cancer. PMID: 26101717 Ref: KNOCKDOWN OF CASEIN KINASE 1e INHIBITS CELL PROLIFERATION AND INVASION OF COLORECTAL CANCER CELLS VIA INHIBITION OF THE Wnt/beta-CATENIN SIGNALING. PMID: 26122218 Ref: Microarray analysis of anti-cancer effects of docosahexaenoic acid on human colon cancer model in nude mice. PMID: 26131080 Ref: Integrin alphavbeta6 sustains and promotes tumor invasive growth in colon cancer progression. PMID: 26139991 Ref: B7H3 promotes cell migration and invasion through the Jak2/Stat3/MMP9 signaling pathway in colorectal cancer. PMID: 26151358 Ref: Up-regulation of microRNA-302a inhibited the proliferation and invasion of colorectal cancer cells by regulation of the MAPK and PI3K/Akt signaling pathways. PMID: 26191138 Ref: Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells. PMID: 26214321 Ref: Serum matrix metalloproteinase-9 in colorectal cancer family-risk population screening. 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PMID: 26379350 Ref: Immunohistochemical expression of Notch1, Jagged1, NF-kappaB and MMP-9 in colorectal cancer patients and the relationship to clinicopathological parameters. PMID: 26406415 Ref: The pattern of CD44 and matrix metalloproteinase 9 expression is a useful predictor of ulcerative colitis-associated dysplasia and neoplasia. PMID: 26420348 Ref: 1,25(OH)2D3 attenuates TGF-beta1/beta2-induced increased migration and invasion via inhibiting epithelial-mesenchymal transition in colon cancer cells. PMID: 26523511 Ref: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. PMID: 26590805 Ref: microRNA-20a enhances the epithelial-to-mesenchymal transition of colorectal cancer cells by modulating matrix metalloproteinases. PMID: 26622375 Ref: The assessment of matrix metalloproteinase-9 expression and angiogenesis in colorectal cancer. 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Ref: Bisphenol a exposure promotes the migration of NCM460 cells via estrogen receptor-mediated integrin beta1/MMP-9 pathway. PMID: 25534675 Ref: Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy. PMID: 26457379 Ref: A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9. PMID: 26497206 Ref: BAG3 regulates cell proliferation, migration, and invasion in human colorectal cancer. PMID: 26577854 Ref: NIK- and IKKbeta-binding protein promotes colon cancer metastasis by activating the classical NF-kappaB pathway and MMPs. PMID: 26596835 Ref: Plasma matrix metalloproteinase 9 as an early surrogate biomarker of advanced colorectal neoplasia. PMID: 26601990 Ref: Regulatory effects of DeltaFosB on proliferation and apoptosis of MCF-7 breast cancer cells. PMID: 26608367 Ref: Legume seeds and colorectal cancer revisited: Protease inhibitors reduce MMP-9 activity and colon cancer cell migration. PMID: 26616921 Ref: FAM172A is a tumor suppressor in colorectal carcinoma. PMID: 26637224 Ref: MicroRNA7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase. PMID: 26648422 Ref: Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway. PMID: 26677144 Ref: Study on the inhibition of hyperthermic CO(2) pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism. PMID: 26718327 Ref: CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling. PMID: 26719016 Ref: Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer. PMID: 26754532 Ref: Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX. PMID: 26790967 Ref: High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma. PMID: 26814712 Ref: Long non-coding RNA AK027294 involves in the process of proliferation, migration, and apoptosis of colorectal cancer cells. PMID: 26820130 Ref: microRNA-497 inhibits invasion and metastasis of colorectal cancer cells by targeting vascular endothelial growth factor-A. PMID: 26840372 Ref: Norcantharidin Suppresses Colon Cancer Cell Epithelial-Mesenchymal Transition by Inhibiting the alphavbeta6-ERK-Ets1 Signaling Pathway. PMID: 26846153 Ref: Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-kappaB signal pathway. PMID: 26847533 Ref: Regulation of colorectal cancer cell epithelial to mesenchymal transition by the renin angiotensin system. PMID: 26849969 Ref: Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells. PMID: 26864323 Ref: Baicalein inhibits the migration and invasion of colorectal cancer cells via suppression of the AKT signaling pathway. PMID: 26870267 Ref: A pilot study on faecal MMP-9: a new noninvasive diagnostic marker of colorectal cancer. PMID: 26908323 Ref: Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis. PMID: 26929650 Ref: Relationship of serum polyunsaturated fatty acids with cytokines in colorectal cancer. PMID: 26937140 Ref: Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells. PMID: 26959057 Ref: Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cancer cells. PMID: 26968633 Ref: MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer. PMID: 26983891 Ref: Knockdown of LI-cadherin alters expression of matrix metalloproteinase-2 and -9 and galectin-3. PMID: 27035870 Ref: Matrix metalloproteinase 9 -1562C/T polymorphism increased protein levels in patients with colorectal cancer in a sample from southeastern Brazil. PMID: 27051027 Ref: An epitope-specific novel anti-EMMPRIN polyclonal antibody inhibits tumor progression. PMID: 27057452 Ref: CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis. PMID: 27058823 Ref: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression. PMID: 27098148 Ref: Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-kappaB and mTOR signaling. PMID: 27106148 Ref: Expression of Migration-Related Genes in Human Colorectal Cancer and Activity of a Disintegrin and Metalloproteinase 17. PMID: 27110571 Ref: [LRRC3B is Downregulated in Non-small Cell Lung Cancer and Connected with Cell Proliferation and Invasion]. PMID: 27118644 Ref: Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway. PMID: 27121420 Ref: ZKSCAN3 Facilitates Liver Metastasis of Colorectal Cancer Associated with CEA-expressing Tumor. PMID: 27127149 Ref: The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer. PMID: 27145365 Ref: An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells. PMID: 27163855 Ref: Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice. PMID: 27187454 Ref: Effects of Panax notoginseng on the Metastasis of Human Colorectal Cancer Cells. PMID: 27222068 Ref: Matrix metalloproteinase (MMP) -2, -7 and -9 promoter polymorphisms in colorectal cancer in ethnic Kashmiri population - A case-control study and a mini review. PMID: 27222481 Ref: An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer. PMID: 27226778 Ref: Silymarin suppressed lung cancer growth in mice via inhibiting myeloid-derived suppressor cells. PMID: 27261626 Ref: Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway. PMID: 27279570 Ref: Quercetin Suppresses the Migration and Invasion in Human Colon Cancer Caco-2 Cells Through Regulating Toll-like Receptor 4/Nuclear Factor-kappa B Pathway. PMID: 27279714 Ref: Recombinant Lactococcus lactis NZ9000 secretes a bioactive kisspeptin that inhibits proliferation and migration of human colon carcinoma HT-29 cells. PMID: 27287327 Ref: Antiproliferative Activity of Triterpene Glycoside Nutrient from Monk Fruit in Colorectal Cancer and Throat Cancer. PMID: 27304964 Ref: Effects of HMGA2 siRNA and doxorubicin dual delivery by chitosan nanoparticles on cytotoxicity and gene expression of HT-29 colorectal cancer cell line. PMID: 27350211 Ref: [Effect of interleukin 17 on invasion of human colon cancer cells]. PMID: 27353107 Ref: Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. PMID: 27367023 Ref: Matrix metalloproteinases MMP1, MMP2, MMP9 and their tissue inhibitors TIMP1, TIMP2, TIMP3 in head and neck cancer: an immunohistochemical study. PMID: 27386931 Ref: Diagnostic Accuracy of Five Different Fecal Markers for the Detection of Precancerous and Cancerous Lesions of the Colorectum. PMID: 27413251 Ref: Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and beta-catenin signaling pathways. PMID: 27422337 Ref: Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening. PMID: 27461255 Ref: gamma-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules. PMID: 27575851 Ref: RUNX3 inhibits the metastasis and angiogenesis of colorectal cancer. PMID: 27633042 Ref: 4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl inhibits angiogenesis by suppressing VEGFR2 and Tie2 phosphorylation. PMID: 27698866 Ref: In vitro inhibition of invasion and metastasis in colon cancer cells by TanIIA. PMID: 27706759 Ref: DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up. PMID: 27709558 Ref: AEG-1 knockdown in colon cancer cell lines inhibits radiation-enhanced migration and invasion in vitro and in a novel in vivo zebrafish model. PMID: 27835571 Ref: Curcumin suppresses colon cancer cell invasion via AMPK-induced inhibition of NF-kappaB, uPA activator and MMP9. PMID: 27895783 Ref: Microarray analysis of differentially-expressed genes and linker genes associated with the molecular mechanism of colorectal cancer. PMID: 27899990 Ref: Chemoprevention of Colon Cancer through Inhibition of Angiogenesis and Induction of Apoptosis by Nonsteroidal Anti-Inflammatory Drugs. PMID: 27910782 Ref: Expressions of Inhibitors of DNA Binding-1 and Matrix Metalloproteinase-9 in Colorectal Adenocarcinoma Tissues and Their Correlations with Microvessel Density. PMID: 28065236 Ref: Particularly interesting Cys-His-rich protein is highly expressed in human intracranial aneurysms and resists aneurysmal rupture. PMID: 28101173 |
Ref: PTRF suppresses the progression of colorectal cancers. PMID: 27203393 Ref: Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. PMID: 27481098 Ref: Genetic disruption of tubulin acetyltransferase, alphaTAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/beta-catenin signaling. PMID: 27836544 Ref: Inhibition of human colorectal cancer metastasis by notoginsenoside R1, an important compound from Panax notoginseng. PMID: 27840961 Ref: Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis. PMID: 27861153 Ref: TUC.338 promotes invasion and metastasis in colorectal cancer. PMID: 27914101 Ref: Chitosan nanoparticles as a dual drug/siRNA delivery system for treatment of colorectal cancer. PMID: 27916629 Ref: The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression. PMID: 27991682 Ref: Influence of microRNA34a on proliferation, invasion and metastasis of HCT116 cells. PMID: 28035390 Ref: Taspine derivative 12k suppressed A549 cell migration through the Wnt/beta-catenin and EphrinB2 signaling pathway. PMID: 28049091 Ref: Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasis. PMID: 28055016 Ref: Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials for antitumor drug delivery. PMID: 28077049 Ref: Inhibitory effect of blue light emitting diode on migration and invasion of cancer cells. PMID: 28098340 Ref: M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases. PMID: 28098359 Ref: Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells. PMID: 28157665 Ref: Enhanced colorectal cancer metastases in the alcohol-injured liver. PMID: 28168393 Ref: Amino-terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer. PMID: 28178391 Ref: Peripheral blood leucocytes show differential expression of tumour progression-related genes in colorectal cancer patients who have a postoperative intra-abdominal infection: a prospective matched cohort study. PMID: 28214365 Ref: USP39 promotes colorectal cancer growth and metastasis through the Wnt/beta-catenin pathway. PMID: 28259917 Ref: The anti-metastatic effect of baicalein on colorectal cancer. PMID: 28259937 Ref: Proteins in Soy Might Have a Higher Role in Cancer Prevention than Previously Expected: Soybean Protein Fractions Are More Effective MMP-9 Inhibitors Than Non-Protein Fractions, Even in Cooked Seeds. PMID: 28264435 Ref: Profile of Expression of Genes Encoding Matrix Metallopeptidase 9 (MMP9), Matrix Metallopeptidase 28 (MMP28) and TIMP Metallopeptidase Inhibitor 1 (TIMP1) in Colorectal Cancer: Assessment of the Role in Diagnosis and Prognostication. PMID: 28293015 Ref: ROS-mediated induction of apoptosis by benzoquinone embelin in human colon adenocarcinoma cells HT-29. PMID: 28306533 Ref: Overexpression of Rab1B and MMP9 predicts poor survival and good response to chemotherapy in patients with colorectal cancer. PMID: 28316326 Ref: Anticancer activity of Nelumbo nucifera stamen extract in human colon cancer HCT-116 cells in vitro. PMID: 28454279 Ref: Matrix metalloproteinases in Vietnamese patients with colorectal cancer. PMID: 28454367 Ref: Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities. PMID: 28494341 Ref: Osteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min Mice. PMID: 28505114 Ref: Parthenolide promotes apoptotic cell death and inhibits the migration and invasion of SW620 cells. PMID: 28522946 Ref: Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. PMID: 28549801 Ref: Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo. PMID: 28627695 Ref: The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology. PMID: 28634392 Ref: The association between the serum levels of matrix metalloproteinase 9 and colorectal cancer. PMID: 28644426 Ref: Expression of Twist protein in colorectal carcinoma and its effect on proliferation and invasion of colorectal cancer cells. PMID: 28650334 Ref: MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling. PMID: 28653875 Ref: Low expression of microRNA-320b correlates with tumorigenesis and unfavorable prognosis in glioma. PMID: 28656255 Ref: Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells. PMID: 28688953 Ref: Proliferation and invasion of ovarian cancer cells are suppressed by knockdown of TRIM11. PMID: 28781653 Ref: Flavanols from Japanese quince (Chaenomeles japonica) fruit suppress expression of cyclooxygenase-2, metalloproteinase-9, and nuclear factor-kappaB in human colon cancer cells. PMID: 28787469 Ref: IL-32alpha-induced inflammation constitutes a link between obesity and colon cancer. PMID: 28811968 Ref: Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers. PMID: 28833104 Ref: The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment. PMID: 28893556 Ref: Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2. PMID: 28931592 Ref: Ca(2+)/calmodulin-dependent protein kinase II regulates colon cancer proliferation and migration via ERK1/2 and p38 pathways. PMID: 28970726 Ref: GSK-3beta inhibitor 6-bromo-indirubin-3'-oxime promotes both adhesive activity and drug resistance in colorectal cancer cells. PMID: 29039496 Ref: Inhibition of BAMBI reduces the viability and motility of colon cancer via activating TGF-beta/Smad pathway in vitro and in vivo. PMID: 29085481 Ref: Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation. PMID: 29113214 Ref: ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells. PMID: 29151941 Ref: Scutellaria barbata D. Don inhibits migration and invasion of colorectal cancer cells via suppression of PI3K/AKT and TGF-beta/Smad signaling pathways. PMID: 29285087 Ref: NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway. PMID: 29296214 Ref: Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/beta-catenin signaling pathway. PMID: 29340086 Ref: Function of miR-146a-5p in Tumor Cells As a Regulatory Switch between Cell Death and Angiogenesis: Macrophage Therapy Revisited. PMID: 29354134 Ref: Matrix Metalloproteinase-2 and -9, Lactate, and Malate Dehydrogenase and Lipid Peroxides in Sera of Patients with Colorectal Carcinoma. PMID: 29687772 |
Ref: Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma. PMID: 28600709 Ref: Epithelialmesenchymal transition in colorectal carcinoma cells is mediated by DEK/IMP3. PMID: 29115492 Ref: Overexpression of CCDC34 in colorectal cancer and its involvement in tumor growth, apoptosis and invasion. PMID: 29115580 Ref: Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in Vivo. PMID: 29237264 Ref: Down-regulation of FN1 inhibits colorectal carcinogenesis by suppressing proliferation, migration, and invasion. PMID: 29274284 Ref: Emodin inhibits colon cancer cell invasion and migration by suppressing epithelialmesenchymal transition via the Wnt/beta-catenin pathway. PMID: 29301594 Ref: RNA interference-mediated silencing of aquaporin (AQP)-5 hinders angiogenesis of colorectal tumor by suppressing the production of vascular endothelial growth factor. PMID: 29322789 Ref: Up-regulation of miR-324-5p inhibits proliferation and invasion of colorectal cancer cells by targeting ELAVL1. PMID: 29386086 Ref: Tea Polysaccharide Prevents Colitis-Associated Carcinogenesis in Mice by Inhibiting the Proliferation and Invasion of Tumor Cells. PMID: 29419740 Ref: Platelet-derived growth factor-D promotes colorectal cancer cell migration, invasion and proliferation by regulating Notch1 and matrix metalloproteinase-9. PMID: 29434852 Ref: MACC1 and HGF are associated with survival in patients with gastric cancer. PMID: 29435059 Ref: Down-regulation of miRNA-320c promotes tumor growth and metastasis and predicts poor prognosis in human glioma. PMID: 29438779 Ref: The clinical significance and biological function of tropomyosin 4 in colon cancer. 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