Primary Site >> Biliary tract Cancer
Gene >> MMP9
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Ref: Expression pattern of matrix metalloproteinases in human liver. PMID: 7632822 |
Ref: Expression of immunoreactive matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human normal livers and primary liver tumors. PMID: 8675149 |
Ref: Expression of matrix metalloproteinase-9 in surgically resected intrahepatic cholangiocarcinoma. PMID: 10568183 |
Ref: Expression of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in intraductal and nonintraductal growth type of cholangiocarcinoma. PMID: 14687144 Ref: Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma. PMID: 15213623 Ref: Immunohistochemical study of characteristics of bile duct dysplasia evaluated on the basis of expression of metastasis/invasion-related factors and p53. PMID: 15619017 Ref: A MEK inhibitor (U0126) markedly inhibits direct liver invasion of orthotopically inoculated human gallbladder cancer cells in nude mice. PMID: 15743030 |
Ref: [Expression of epidermal growth factor receptor, ErbB2 and matrix metalloproteinase-9 in hepatolithiasis and cholangiocarcinoma]. PMID: 15665568 Ref: Expression of RECK gene and MMP-9 in hilar cholangiocarcinoma and its clinical significance. PMID: 16463672 |
Ref: Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis. PMID: 18227728 Ref: Two pathologic types of hepatocellular carcinoma with lymph node metastasis with distinct prognosis on the basis of CK19 expression in tumor. PMID: 18412155 Ref: The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters. PMID: 18630474 |
Ref: Enhanced expression of trophinin promotes invasive and metastatic potential of human gallbladder cancer cells. PMID: 18846386 Ref: Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. PMID: 19218340 Ref: The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression PMID: 19330734 Ref: Inflammation and tumor progression: a lesson from TNF-alpha-dependent FAK signaling in cholangiocarcinoma. PMID: 19347283 Ref: Detection of serum MMP-7 and MMP-9 in cholangiocarcinoma patients: evaluation of diagnostic accuracy. PMID: 19405942 Ref: Fascin is involved in tumor necrosis factor-alpha-dependent production of MMP9 in cholangiocarcinoma. PMID: 19721413 |
Ref: Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion. PMID: 20135719 Ref: Expression of LAPTM4B in gallbladder carcinoma cells: the role in invasive potential. PMID: 20583413 |
Ref: Downregulation of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) is associated with enhanced expression of matrix metalloproteinases and cholangiocarcinoma metastases. PMID: 21076843 Ref: Nuclear expression of S100A4 calcium-binding protein increases cholangiocarcinoma invasiveness and metastasization. PMID: 21618579 |
Ref: Plasma hydroxyproline, MMP-7 and collagen I as novel predictive risk markers of hepatobiliary disease-associated cholangiocarcinoma. PMID: 21935919 Ref: Overexpression of ECM1 contributes to migration and invasion in cholangiocarcinoma cell. PMID: 22489696 Ref: Higher risk of matrix metalloproteinase (MMP-2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP-2) genetic variants to gallbladder cancer. PMID: 22621753 Ref: Epigenetic regulation of miR-124 by hepatitis C virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3. PMID: 22819820 Ref: Ethyl pyruvate administration suppresses growth and invasion of gallbladder cancer cells via downregulation of HMGB1-RAGE axis. PMID: 23298486 Ref: TNP-470, a methionine aminopeptidase-2 inhibitor, inhibits cell proliferation, migration and invasion of human cholangiocarcinoma cells in vitro. PMID: 23480758 Ref: Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells. PMID: 23480772 |
Ref: High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery. PMID: 23132676 Ref: Characterization of two novel cell lines with distinct heterogeneity derived from a single human bile duct carcinoma. PMID: 23382894 Ref: Preclinical evaluation of sorafenib-eluting stent for suppression of human cholangiocarcinoma cells. PMID: 23658488 Ref: Annexin A1: A new immunohistological marker of cholangiocarcinoma. PMID: 23674846 Ref: Oncogenic activity of retinoic acid receptor gamma is exhibited through activation of the Akt/NF-kappaB and Wnt/beta-catenin pathways in cholangiocarcinoma. PMID: 23798555 Ref: MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell line. PMID: 23922722 Ref: Down-regulation of Gab1 inhibits cell proliferation and migration in hilar cholangiocarcinoma. PMID: 24312291 |
Ref: Hedgehog signaling pathway is a potential therapeutic target for gallbladder cancer. PMID: 24438533 Ref: Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo. PMID: 24725816 Ref: A multigenic approach to evaluate genetic variants of PLCE1, LXRs, MMPs, TIMP, and CYP genes in gallbladder cancer predisposition. PMID: 24863943 Ref: Capsaicin suppresses the migration of cholangiocarcinoma cells by down-regulating matrix metalloproteinase-9 expression via the AMPK-NF-kappaB signaling pathway. PMID: 25217963 Ref: High expression of matrix metalloproteinase-9 indicates poor prognosis in human hilar cholangiocarcinoma. PMID: 25337264 |
Ref: The expression of S100A4 protein in human intrahepatic cholangiocarcinoma: clinicopathologic significance and prognostic value. PMID: 24985031 Ref: Raf kinase inhibitor protein inhibits cholangiocarcinoma cell metastasis by downregulating matrix metalloproteinase 9 and upregulating tissue inhibitor of metalloproteinase 4 expression. PMID: 25435928 Ref: Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma. PMID: 25623530 Ref: Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-kappaB-mediated survival signaling pathways in human gallbladder cancer cells. PMID: 25633045 Ref: Fibronectin promotes cell proliferation and invasion through mTOR signaling pathway activation in gallbladder cancer. PMID: 25657110 Ref: RNA sequencing reveals differentially expressed genes as potential diagnostic and prognostic indicators of gallbladder carcinoma. PMID: 25970782 Ref: Gab1 regulates proliferation and migration through the PI3K/Akt signaling pathway in intrahepatic cholangiocarcinoma. PMID: 26014518 Ref: Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination. PMID: 26325075 Ref: Interleukin-8 is a prognostic indicator in human hilar cholangiocarcinoma. PMID: 26339407 |
Ref: Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway. PMID: 25037728 Ref: SPARCL1 is a novel predictor of tumor recurrence and survival in hilar cholangiocarcinoma. PMID: 26490986 Ref: Blood expression of matrix metalloproteinases 8 and 9 and of their inducers S100A8 and S100A9 supports diagnosis and prognosis of PDAC-associated diabetes mellitus. PMID: 26923392 Ref: Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines. PMID: 26935541 Ref: Knockdown of RHOC by shRNA suppresses invasion and migration of cholangiocellular carcinoma cells via inhibition of MMP2, MMP3, MMP9 and epithelial-mesenchymal transition. PMID: 27108649 Ref: Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor. PMID: 27211817 Ref: Scabraside D Derived from Sea Cucumber Induces Apoptosis and Inhibits Metastasis via iNOS and STAT-3 Expression in Human Cholangiocarcinoma Xenografts. PMID: 27221911 Ref: SHP2 and UGP2 are Biomarkers for Progression and Poor Prognosis of Gallbladder Cancer. PMID: 27389087 Ref: Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway. PMID: 27637083 |
Ref: Establishment and characterization of a novel highly aggressive gallbladder cancer cell line, TJ-GBC2. PMID: 28194091 Ref: Tropomyosin-related kinase B mediated signaling contributes to the induction of malignant phenotype of gallbladder cancer. PMID: 28423707 Ref: 14-3-3sigma downregulation suppresses ICC metastasis via impairing migration, invasion, and anoikis resistance of ICC cells. PMID: 28482619 Ref: Long Noncoding RNA AFAP1-AS1 Promoted Tumor Growth and Invasion in Cholangiocarcinoma. PMID: 28535506 Ref: Blocking ERK1/2 signaling impairs TGF-beta1 tumor promoting function but enhances its tumor suppressing role in intrahepatic cholangiocarcinoma cells. PMID: 28959141 |
Ref: Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway. PMID: 29170841 Ref: Role of cantharidin in the activation of IKKalpha/IkappaBalpha/NFkappaB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines. PMID: 29620225 Ref: Alpha-L-Fucosidase Serves as a Prognostic Indicator for Intrahepatic Cholangiocarcinoma and Inhibits Its Invasion Capacity. PMID: 29682557 Ref: Knockdown of TRIM31 suppresses proliferation and invasion of gallbladder cancer cells by down-regulating MMP2/9 through the PI3K/Akt signaling pathway. PMID: 29864908 Ref: Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells. PMID: 30001777 |