Primary Site >> Colorectal Cancer
Gene >> MMP7
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Ref: Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line. PMID: 2253219 |
Ref: Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. PMID: 1793490 |
Ref: Expression of MMP-7(PUMP-1) mRNA in human colorectal cancers. PMID: 8514452 |
Ref: Polyamine-dependent expression of the matrix metalloproteinase matrilysin in a human colon cancer-derived cell line. PMID: 7945802 Ref: Expression of matrilysin mRNA in colorectal adenomas and its induction by truncated fibronectin. PMID: 8002999 Ref: Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. PMID: 8062282 Ref: Matrix-degrading metalloproteinases in tumor progression. PMID: 8983072 |
Ref: Suppression of matrilysin inhibits colon cancer cell invasion in vitro. PMID: 7705951 Ref: Overexpression of matrix metalloproteinase-7 mRNA in human colon carcinomas. PMID: 7889484 Ref: Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties. PMID: 7896811 Ref: Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells. PMID: 8531010 Ref: The expression of mmp-7 messenger-RNA in primary and metastatic human colorectal adenocarcinoma. PMID: 21597750 |
Ref: Enhanced secretion and activation of matrilysin during malignant conversion of human colorectal epithelium and its relationship with invasive potential of colon cancer cells. PMID: 8608568 Ref: [Genetic diagnosis of colorectal cancer]. PMID: 8727369 Ref: Matrilysin is associated with progression of colorectal tumor. PMID: 8913260 |
Ref: Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. PMID: 9037065 Ref: Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor. PMID: 9062395 Ref: Modulation of matrix metalloproteinase-7 (matrilysin) secretion in coculture of human colon carcinoma cells with fibroblasts from orthotopic and ectopic organs. PMID: 9220495 Ref: Expression of matrilysin in vascular endothelial cells adjacent to matrilysin-producing tumors. PMID: 9247287 |
Ref: Preoperative estimation of neural invasion in rectal carcinoma. PMID: 9458297 Ref: Detection of regional lymph node metastases in colon cancer by using RT-PCR for matrix metalloproteinase 7, matrilysin. PMID: 9502072 Ref: Inhibitory effect of matrilysin antisense oligonucleotides on human colon cancer cell invasion in vitro. PMID: 9609101 Ref: Matrilysin-specific antisense oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude mouse model. PMID: 9626346 |
Ref: Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms. PMID: 10204802 Ref: Matrilysin as a target for chemotherapy for colon cancer: use of antisense oligonucleotides as antimetastatic agents. PMID: 10357559 Ref: Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers. PMID: 10403738 Ref: beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. PMID: 10514384 |
Ref: Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas. PMID: 10702403 Ref: [beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma]. PMID: 11217438 Ref: [Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]. PMID: 11832095 |
Ref: The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. PMID: 11158322 Ref: PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. PMID: 11274170 Ref: Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. PMID: 11326276 Ref: [Future scope for gene therapy for liver metastasis of colon cancer]. PMID: 11394006 Ref: Retinoic acids reduce matrilysin (matrix metalloproteinase 7) and inhibit tumor cell invasion in human colon cancer. PMID: 11399950 Ref: Clinicopathologic and prognostic significance of matrilysin expression at the invasive front in human colorectal cancers. PMID: 11494227 Ref: Matrilysin stimulates DNA synthesis of cultured vascular endothelial cells and induces angiogenesis in vivo. PMID: 11597792 Ref: Expression of putative anticancer targets in familial adenomatous polyposis and its association with the APC mutation status. PMID: 11713587 Ref: [The Rudolf Virchow Prize 2001. The role of the oncoprotein beta-catenin ni the progression of colorectal cancers]. PMID: 11894405 |
Ref: Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. PMID: 11774242 Ref: Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer. PMID: 11781281 Ref: Matrix metalloproteinase-7 expression in colorectal cancer liver metastases: evidence for involvement of MMP-7 activation in human cancer metastases. PMID: 11801551 Ref: Beta-catenin--a linchpin in colorectal carcinogenesis? PMID: 11839557 Ref: Effect of preoperative radiotherapy on matrilysin gene expression in rectal cancer. PMID: 11872342 Ref: Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. PMID: 11943708 Ref: Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma. PMID: 11953860 Ref: Decreased synthesis of matrix metalloproteinase-7 and adhesion to the extracellular matrix proteins of human colon cancer cells treated with troglitazone. PMID: 12027200 Ref: Matrilysin (matrix metalloproteinase-7) expression in ulcerative colitis-related tumorigenesis. PMID: 12112311 Ref: Prediction of distant metastasis by using reverse transcriptase-polymerase chain reaction for epithelial and variant CD44 mRNA in the peripheral blood of patients with colorectal cancer. PMID: 12215164 Ref: Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. PMID: 12481159 |
Ref: The angiogenic switch of human colon cancer occurs simultaneous to initiation of invasion. PMID: 12469136 Ref: Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer. PMID: 12533830 Ref: Clinical utility of grading criteria for submucosal invasion in the prognosis of T1 colorectal carcinomas. PMID: 12560920 Ref: Investigations for a multi-marker RT-PCR to improve sensitivity of disseminated tumor cell detection. PMID: 12680210 Ref: [Prognostic significance of the molecular markers in human gastrointestinal cancer]. PMID: 12690634 Ref: Coexpression of matrilysin and laminin-5 gamma2 chain may contribute to tumor cell migration in colorectal carcinomas. PMID: 12870781 Ref: Association of ets-related transcriptional factor E1AF expression with tumour progression and overexpression of MMP-1 and matrilysin in human colorectal cancer. PMID: 12898592 Ref: [Function of MMP-7 in colorectal cancer]. PMID: 14574883 Ref: Colorectal carcinoma susceptibility and metastases are associated with matrix metalloproteinase-7 promoter polymorphisms. PMID: 14578330 Ref: Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse model. PMID: 14647460 Ref: New insights into the roles of matrix metalloproteinases in colorectal cancer development and progression. PMID: 14648655 Ref: Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas. PMID: 14666620 Ref: Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes. PMID: 14691307 |
Ref: Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity. PMID: 14556651 Ref: Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3. PMID: 14744783 Ref: Relationship between matrix metalloproteinase-7 and pit pattern in early stage colorectal cancer. PMID: 14997136 Ref: Role of matrix metalloproteinases (MMPs) in colorectal cancer. PMID: 15000152 Ref: Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. PMID: 15059925 Ref: Simultaneous determination of matrix metalloproteinase (MMP)-7, MMP-1, -3, and -13 gene expression by multiplex PCR in colorectal carcinomas. PMID: 15103490 Ref: Epidermal growth factor upregulates matrix metalloproteinase-7 expression through activation of PEA3 transcription factors. PMID: 15138601 Ref: Truncated mouse adenomatous polyposis coli reduces connexin32 content and increases matrilysin secretion from Paneth cells. PMID: 15196546 Ref: The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse. PMID: 15201952 Ref: Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma. PMID: 15235586 Ref: Polyploidisation of metastatic colon carcinoma cells by microtubule and tubulin interacting drugs: effect on proteolytic activity and invasiveness. PMID: 15375554 Ref: Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis. PMID: 15585629 Ref: Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers. PMID: 15623598 Ref: Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells. PMID: 15623600 Ref: [The significance of beta-catenin and matrix metalloproteinase-7 expression in colorectal adenoma and carcinoma]. PMID: 15634446 |
Ref: Connective tissue growth factor inhibits metastasis and acts as an independent prognostic marker in colorectal cancer. PMID: 15633118 Ref: Proliferative effects of apical, but not basal, matrix metalloproteinase-7 activity in polarized MDCK cells. PMID: 15652345 Ref: Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. PMID: 15695237 Ref: Nobiletin, a citrus flavonoid, down-regulates matrix metalloproteinase-7 (matrilysin) expression in HT-29 human colorectal cancer cells. PMID: 15725655 Ref: E1A-F is overexpressed early in human colorectal neoplasia and associated with cyclooxygenase-2 and matrix metalloproteinase-7. PMID: 15800927 Ref: (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells. PMID: 15860507 Ref: Expression of matrix metalloproteinase 7, laminin and type IV collagen-associated liver metastasis in human colorectal cancer: immunohistochemical approach. PMID: 15966224 Ref: Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells. PMID: 16052481 Ref: EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells. PMID: 16053920 Ref: Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples. PMID: 16101153 Ref: Pericellular activation of proMMP-7 (promatrilysin-1) through interaction with CD151. PMID: 16200075 Ref: Tumour matrilysin expression predicts metastatic potential of stage I (pT1) colon and rectal cancers. PMID: 16284286 Ref: Clinicopathologic and prognostic significance of MMP-7 (matrilysin) expression in human rectal cancer. PMID: 16314344 Ref: Expressions of matrix metalloproteinase-7 and -9 and their prognostic significances in rectal cancer. PMID: 19956372 |
Ref: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. PMID: 16401477 Ref: Identification of early-stage colorectal cancer patients at risk of relapse post-resection by immunobead reverse transcription-PCR analysis of peritoneal lavage fluid for malignant cells. PMID: 16428481 Ref: Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma. PMID: 16474169 Ref: Binding of active matrilysin to cell surface cholesterol sulfate is essential for its membrane-associated proteolytic action and induction of homotypic cell adhesion. PMID: 16476739 Ref: Colorectal carcinoma: from tumorigenesis to treatment. PMID: 16501890 Ref: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. PMID: 16619535 Ref: Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway. PMID: 16648570 Ref: Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. PMID: 16691544 Ref: Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis. PMID: 16733264 Ref: Biomarker selection for detection of occult tumour cells in lymph nodes of colorectal cancer patients using real-time quantitative RT-PCR. PMID: 16755296 Ref: Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas. PMID: 16857787 Ref: Intracellular expression of the T-cell factor-1 RNA aptamer as an intramer. PMID: 16985077 Ref: Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential? PMID: 17075343 Ref: Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma. PMID: 17125518 Ref: Matrilysin 1 influences colon carcinoma cell migration by cleavage of the laminin-5 beta3 chain. PMID: 17145868 Ref: Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice. PMID: 17151446 |
Ref: Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer. PMID: 16896992 Ref: Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. PMID: 17183061 Ref: Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. PMID: 17222808 Ref: A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo. PMID: 17316082 Ref: Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix. PMID: 17359288 Ref: Serum matrix metalloproteinase 7 levels identifies poor prognosis advanced colorectal cancer patients. PMID: 17487834 Ref: Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels. PMID: 17516864 Ref: Peroxisome proliferator-activated receptor gamma agonists inhibit the proliferation and invasion of human colon cancer cells. PMID: 17551074 Ref: Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. PMID: 17608852 Ref: Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples. PMID: 17649785 Ref: Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer. PMID: 17657837 Ref: Clinical impact of matrix metalloproteinase-7 mRNA expression in the invasive front and inner surface of tumor tissues in patients with colorectal cancer. PMID: 17676380 Ref: [Expression and clinical significance of matrilysin (MMP-7) in human rectal cancer]. PMID: 17718429 Ref: Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation. PMID: 17721919 Ref: Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells. PMID: 17928719 Ref: [Regulation of promatrilysin expression by tissue factor/actived coagulation factor VII complex in LoVo colon cancer cell line]. PMID: 17940558 Ref: Matrix metalloproteinases 7 and 9 and their types 1 and 4 tissue inhibitors in tumors and plasma of patients with colorectal cancer. PMID: 18214300 Ref: Association of E1AF mRNA expression with tumor progression and matrilysin in human rectal cancer. PMID: 18511876 |
Ref: Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate. PMID: 18212756 Ref: Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice. PMID: 18499699 Ref: The FVIIa-tissue factor complex induces the expression of MMP7 in LOVO cells in vitro. PMID: 18548257 Ref: Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: insulin-like growth factor-1 re PMID: 18636198 Ref: E-cadherin, beta-catenin adhesion complex and relation to matrilysin expression in pT3 rectosigmoid cancers. PMID: 18674869 Ref: Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat. PMID: 18681964 Ref: Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces. PMID: 18721140 Ref: A new formula for predicting liver metastasis in patients with colorectal cancer: immunohistochemical analysis of a large series of 439 surgically resected cases. PMID: 18728370 Ref: Identification of amino acid residues of matrix metalloproteinase-7 essential for binding to cholesterol sulfate. PMID: 18955490 Ref: Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors. PMID: 18992165 Ref: [Effects of tamoxifen on apoptosis and matrix metalloproteinase-7 expression in estrogen receptor beta-positive colonic cancer cell line HT-29]. PMID: 19000448 Ref: Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis. PMID: 19016757 |
Ref: Src activity alters alpha3 integrin expression in colon tumor cells. PMID: 18839319 Ref: Suppression of beta-catenin signaling by liver X receptor ligands. PMID: 18983830 Ref: Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas. PMID: 19002110 Ref: A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways. PMID: 19037088 Ref: Serum IGF-I, IGFBP-3, and matrix metalloproteinase-7 levels and acquired chemo-resistance in advanced colorectal cancer. PMID: 19109398 Ref: Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4. PMID: 19151752 Ref: Matrilysin (MMP-7) cleaves C-type lectin domain family 3 member A (CLEC3A) on tumor cell surface and modulates its cell adhesion activity. PMID: 19173304 Ref: Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells. PMID: 19221016 Ref: Inhibition of hyaluronan synthases decreases matrix metalloproteinase-7 (MMP-7) expression and activity. PMID: 19231585 Ref: Serum matrilysin levels predict outcome in curatively resected colorectal cancer patients. PMID: 19259740 Ref: The role of MMP7 and its cross-talk with the FAS/FASL system during the acquisition of chemoresistance to oxaliplatin. PMID: 19266094 Ref: Smad4 restoration leads to a suppression of Wnt/beta-catenin signaling activity and migration capacity in human colon carcinoma cells. PMID: 19284991 Ref: Differences in the gene expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in primary colorectal tumors and their synchronous liver metastases. PMID: 19331134 Ref: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer. PMID: 19421758 Ref: Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expression. PMID: 19426720 Ref: Fecal cyclooxygenase 2 plus matrix metalloproteinase 7 mRNA assays as a marker for colorectal cancer screening. PMID: 19505922 Ref: Measuring the combinatorial expression of solute transporters and metalloproteinases transcripts in colorectal cancer. PMID: 19689820 Ref: [Expression and clinical significance of survivin and matrix metalloproteinase-7 in colon cancer]. PMID: 19728912 Ref: MMP7 expression regulated by endocrine therapy in ERbeta-positive colon cancer cells. PMID: 19785773 Ref: Syndecan-2 functions as a docking receptor for pro-matrix metalloproteinase-7 in human colon cancer cells. PMID: 19858218 Ref: [Pathologic study of circumferential margin involvement in middle and lower rectal cancer]. PMID: 20137717 |
Ref: The tumor-associated antigen 90K/Mac-2-binding protein secreted by human colon carcinoma cells enhances extracellular levels of promatrilysin and is a novel substrate of matrix metalloproteinases-2, -7 (matrilysin) and -9: Implications of proteolytic clea PMID: 19665518 Ref: Coincident expression of beta-catenin and cyclin D1 in endometrial stromal tumors and related high-grade sarcomas. PMID: 19898427 Ref: A comparative study of protein expression in primary colorectal cancer and synchronous hepatic metastases: the significance of matrix metalloproteinase-1 expression as a predictor of liver metastasis. PMID: 20095886 Ref: Effects of Monascus-fermented rice extract on malignant cell-associated neovascularization and intravasation determined using the chicken embryo chorioallantoic membrane model. PMID: 20356949 Ref: MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway. PMID: 20372795 Ref: Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis. PMID: 20428773 Ref: Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. PMID: 20459814 Ref: Thymosin beta4 regulates migration of colon cancer cells by a pathway involving interaction with Ku80. PMID: 20536451 Ref: Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases. PMID: 20572035 Ref: Regulation of osteopontin and related proteins in rat CC531 colorectal cancer cells. PMID: 20596651 Ref: Association of matrix metalloproteinases 1, 7, and 9 gene polymorphisms with genetic susceptibility to colorectal carcinoma in a Han Chinese population. PMID: 20662554 Ref: Prognostic impact of ERbeta and MMP7 expression on overall survival in colon cancer. PMID: 20680712 Ref: Overexpression of MMP-13 gene in colorectal cancer with liver metastasis. PMID: 20683000 Ref: Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer. PMID: 20716165 |
Ref: Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death. PMID: 20980803 Ref: Co-expression of matrix metalloproteinase-7 (MMP-7) and phosphorylated insulin growth factor receptor I (pIGF-1R) correlates with poor prognosis in patients with wild-type KRAS treated with cetuximab or panitumumab: a GEMCAD study. PMID: 21099348 Ref: Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab. PMID: 21104178 Ref: Peptides from Lactobacillus hydrolysates of bovine milk caseins inhibit prolyl-peptidases of human colon cells. PMID: 21126072 Ref: MMP-7 as a prognostic marker in colorectal cancer. PMID: 21207220 Ref: Loss of E-cadherin independently predicts the lymph node status in colorectal cancer. PMID: 21233674 Ref: Early modulation of gene expression used as a biomarker for chemoprevention in a preclinical model of colon carcinogenesis. PMID: 21255184 Ref: Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. PMID: 21273532 Ref: Apoptotic Cell Death and Inhibition of Wnt/beta-Catenin Signaling Pathway in Human Colon Cancer Cells by an Active Fraction (HS7) from Taiwanofungus camphoratus. PMID: 21423639 Ref: A paraptosis-like cell death induced by delta-tocotrienol in human colon carcinoma SW620 cells is associated with the suppression of the Wnt signaling pathway. PMID: 21453743 Ref: Gene expression profile can predict pathological response to preoperative chemoradiotherapy in rectal cancer. PMID: 21471518 Ref: Substrate optimization and clinical validation of reporter peptides for MS-based protease profiling in serum specimens: a new approach for diagnosis of malignant disease. PMID: 21503574 Ref: Digital analysis of the expression levels of multiple colorectal cancer-related genes by multiplexed digital-PCR coupled with hydrogel bead-array. PMID: 21509397 Ref: Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer. PMID: 21664646 Ref: Differential effects of anti-metastatic mechanism of Tian-Xian liquid (TXL) and its bioactive fractions on human colorectal cancer models. PMID: 21669277 Ref: Prognostic and predictive potential molecular biomarkers in colon cancer. PMID: 21696062 Ref: Dimerumic acid inhibits SW620 cell invasion by attenuating H(2)O(2)-mediated MMP-7 expression via JNK/C-Jun and ERK/C-Fos activation in an AP-1-dependent manner. PMID: 21814482 Ref: Matrix metalloproteinase-2 and -7 expression in colorectal cancer. PMID: 21829768 Ref: Calcium prevents tumorigenesis in a mouse model of colorectal cancer. PMID: 21857934 Ref: Cancer chemopreventive effects of lycopene: suppression of MMP-7 expression and cell invasion in human colon cancer cells. PMID: 21923160 Ref: Effect of sulindac sulfide on metallohydrolases in the human colon cancer cell line HT-29. PMID: 21991341 Ref: Histopathological predictors of regional lymph node metastasis at the invasive front in early colorectal cancer. PMID: 22034887 Ref: A/G Polymorphism of the MMP-7 Gene Promoter Region in Colorectal Cancer. PMID: 22246095 Ref: Rosiglitazone and retinoic acid inhibit proliferation and induce apoptosis in the HCT-15 human colorectal cancer cell line. PMID: 22977519 |
Ref: Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell. PMID: 22076613 Ref: Phosphatase of regenerating liver-3 promotes migration and invasion by upregulating matrix metalloproteinases-7 in human colorectal cancer cells. PMID: 22131018 Ref: Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: clinical implications. PMID: 22159423 Ref: The matrix metalloproteinase-7 regulates the extracellular shedding of syndecan-2 from colon cancer cells. PMID: 22227189 Ref: Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation. PMID: 22361730 Ref: Expression and prognostic value of matrix metalloproteinase-7 in colorectal cancer. PMID: 22631636 Ref: Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis. PMID: 22735354 Ref: Small interfering RNA-mediated downregulation of beta-catenin inhibits invasion and migration of colon cancer cells in vitro. PMID: 22739727 Ref: High levels of serum VEGF and TIMP-1 are correlated with colon cancer liver metastasis and intrahepatic recurrence after liver resection. PMID: 22807974 Ref: Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer. PMID: 22961879 Ref: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. PMID: 23251453 |
Ref: Clinical significance of MMP-7 and PTEN expression in colorectal cancer. PMID: 22944341 Ref: Evaluation of alpha 1-antitrypsin and the levels of mRNA expression of matrix metalloproteinase 7, urokinase type plasminogen activator receptor and COX-2 for the diagnosis of colorectal cancer. PMID: 23300952 Ref: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells. PMID: 23333577 Ref: Prognostic role of tumor-associated proteases in colorectal cancer. PMID: 23484202 Ref: Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/beta-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced aberrant crypt foci. PMID: 23545937 Ref: Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis. PMID: 23617763 Ref: S100A8 and S100A9 are associated with colorectal carcinoma progression and contribute to colorectal carcinoma cell survival and migration via Wnt/beta-catenin pathway. PMID: 23637971 Ref: Association between promoters polymorphisms of matrix metalloproteinases and risk of digestive cancers: a meta-analysis. PMID: 23644699 Ref: Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions. PMID: 23682078 Ref: beta,beta-carotene 15,15'-monooxygenase and its substrate beta-carotene modulate migration and invasion in colorectal carcinoma cells. PMID: 23803888 Ref: Multiplexed cytokine profiling of serum for detection of colorectal cancer. PMID: 23837764 Ref: Single-pair fluorescence resonance energy transfer analysis of mRNA transcripts for highly sensitive gene expression profiling in near real time. PMID: 23869556 Ref: A role for WISP2 in colorectal cancer cell invasion and motility. PMID: 23893926 Ref: [Clinical prospects of tumor-associated proteases and their tissue inhibitors investigation in oncologic patient]. PMID: 24000664 Ref: New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers. PMID: 24101199 Ref: The prognostic significance of WNT pathway in surgically-treated colorectal cancer: beta-catenin expression predicts for disease-free survival. PMID: 24123033 Ref: Immunohistochemical expression of MMP-7 protein and its serum level in colorectal cancer. PMID: 24203626 Ref: Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/beta-catenin signal pathway. PMID: 24244343 Ref: Clinicopathological and biological significance of cripto overexpression in human colon cancer. PMID: 24379580 Ref: Tumor associated proteases -- prognostic markers of colorectal cancer. PMID: 24640092 |
Ref: Knockdown of MMP-7 inhibits cell proliferation and enhances sensitivity to 5-Fluorouracil and X-ray irradiation in colon cancer cells. PMID: 23086188 Ref: Epithelial-mesenchymal transition in colorectal cancer tissue of patients with Lynch syndrome. PMID: 24415879 Ref: Survivin promotes the invasion of human colon carcinoma cells by regulating the expression of MMP7. PMID: 24425325 Ref: MMP7 expression in colorectal tumours of different stages. PMID: 24425843 Ref: Matrix metalloproteinase 7 is a useful marker for 5-fluorouracil-based adjuvant chemotherapy in stage II and stage III colorectal cancer patients. PMID: 24469951 Ref: Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer. PMID: 24516991 Ref: Interleukin-1alpha promotes extracellular shedding of syndecan-2 via induction of matrix metalloproteinase-7 expression. PMID: 24613844 Ref: Association of MMP7-181A/G and MMP13-77A/G polymorphisms with colorectal cancer in a Mexican population. PMID: 24615104 Ref: Multiple effects of the special AT-rich binding protein 1 (SATB1) in colon carcinoma. PMID: 24729451 Ref: Elf3 drives beta-catenin transactivation and associates with poor prognosis in colorectal cancer. PMID: 24874735 Ref: Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway. PMID: 24911876 Ref: Expression and activity levels of matrix metalloproteinase-7 and in situ localization of caseinolytic activity in colorectal cancer. PMID: 24930385 Ref: Relationship of serum MMP-7 levels for colorectal cancer: a meta-analysis. PMID: 25060179 Ref: A systematic review and meta-analysis of diagnostic and prognostic serum biomarkers of colorectal cancer. PMID: 25105762 Ref: Radixin enhances colon cancer cell invasion by increasing MMP-7 production via Rac1-ERK pathway. PMID: 25136657 Ref: Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer. PMID: 25321193 Ref: Observation of microvessels and invasion in early colorectal neoplasms on narrow band imaging: combination with CD34 and matrix metalloproteinase-7 expression. PMID: 25357219 |
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