Primary Site >> Pancreatic Cancer
Gene >> MMP2
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Ref: A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies. PMID: 8149645 |
Ref: Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. PMID: 7635566 |
Ref: Expression of collagenase (MMP2), stromelysin (MMP3) and tissue inhibitor of the metalloproteinases (TIMP1) in pancreatic and ampullary disease. PMID: 8611434 |
Ref: Detection of matrix metalloproteinase activity in human pancreatic cancer. PMID: 9086544 Ref: Imbalance of expression of matrix metalloproteinases (MMPs) and tissue inhibitors of the matrix metalloproteinases (TIMPs) in human pancreatic carcinoma. PMID: 9349239 Ref: Expression of matrix metalloproteinases 1 and 2 genes in a possible association with metastatic abilities of human pancreatic cancer cells. PMID: 21533423 |
Ref: Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma. PMID: 9477095 Ref: Two-dimensional zymography for analysis of proteolytic enzymes in human pure pancreatic juice. PMID: 9629915 |
Ref: Matrix metalloproteinase (MMP) inhibition selectively decreases type II MMP activity in a murine model of pancreatic cancer. PMID: 9889060 Ref: Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma. PMID: 9918199 Ref: Matrix metalloproteinase inhibition suppresses MMP-2 activity and activation of PANC-1 cells in vitro. PMID: 10357914 Ref: Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine. PMID: 10383907 |
Ref: Role of MT-MMPs and MMP-2 in pancreatic cancer progression. PMID: 10585576 Ref: Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer. PMID: 10694645 Ref: Effect of matrix metalloproteinase inhibition on pancreatic cancer invasion and metastasis: an additive strategy for cancer control. PMID: 10767785 Ref: Addition of matrix metalloproteinase inhibition to conventional cytotoxic therapy reduces tumor implantation and prolongs survival in a murine model of human pancreatic cancer. PMID: 10866312 Ref: Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis. PMID: 10914717 Ref: Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPs. PMID: 11448066 Ref: High collagenolytic activity in spontaneously highly metastatic variants derived from a human pancreatic cancer cell line (SUIT-2) in nude mice. PMID: 11688961 Ref: In vitro and in vivo matrix metalloproteinase production by pancreatic cancer cells and by distant organs. PMID: 11729853 |
Ref: Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression. PMID: 11181677 Ref: Antitumor effect of a new selective matrix metalloproteinase inhibitor, MMI-166, on experimental pancreatic cancer. PMID: 11291083 Ref: Invasiveness and MMP expression in pancreatic carcinoma. PMID: 11368535 Ref: TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system. PMID: 11410867 Ref: TGF-beta1 promotes liver metastasis of pancreatic cancer by modulating the capacity of cellular invasion. PMID: 11562745 Ref: p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models. PMID: 11585747 Ref: Adenoviral delivery of TIMP1 or TIMP2 can modify the invasive behavior of pancreatic cancer and can have a significant antitumor effect in vivo. PMID: 11773977 |
Ref: MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancer. PMID: 11792149 Ref: TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis. PMID: 11792150 Ref: Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer. PMID: 11854622 Ref: Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck. PMID: 11867199 Ref: Radiation-induced increase in invasive potential of human pancreatic cancer cells and its blockade by a matrix metalloproteinase inhibitor, CGS27023. PMID: 11948136 Ref: Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer. PMID: 11961486 Ref: Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis. PMID: 12142752 Ref: Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trials. PMID: 12167581 Ref: Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. PMID: 12630765 |
Ref: Laparoscopic staging of pancreatic tumors induces increased invasive capacity in vitro. PMID: 12399839 Ref: Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness. PMID: 12591989 Ref: Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells. PMID: 12632066 Ref: RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis. PMID: 12738734 Ref: Regulation of pancreatic stellate cell function in vitro: biological and molecular effects of all-trans retinoic acid. PMID: 12906928 Ref: Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. PMID: 12947321 Ref: Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. PMID: 12947332 Ref: Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype. PMID: 14581380 Ref: Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis. PMID: 14598883 Ref: Detection of type IV collagenase activity in malignant ascites. PMID: 14606104 Ref: Role of matrix metalloproteinases 2 and 9 in determination of invasive potential of pancreatic tumors. PMID: 14968170 |
Ref: Antiangiogenic effect of somatostatin receptor subtype 2 on pancreatic cancer cell line: Inhibition of vascular endothelial growth factor and matrix metalloproteinase-2 expression in vitro. PMID: 14760765 Ref: [Effects of rofecoxib on angiogenesis of pancreatic cancer xenograft in nude mice]. PMID: 15087022 Ref: Inflammatory mechanisms contributing to pancreatic cancer development. PMID: 15166955 Ref: Anti-angiogenic effects of somatostatin receptor subtype 2 on human pancreatic cancer xenografts. PMID: 15205362 Ref: Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. PMID: 15208677 Ref: Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells. PMID: 15257104 Ref: Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity. PMID: 15349101 Ref: [Inhibitory effects of high mobility group box 1 antisense nucleotide on invasion of human pancreatic cancer cell line PCNA-1]. PMID: 15363197 Ref: Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms. PMID: 15479693 Ref: Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2. PMID: 15492268 Ref: Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells. PMID: 15554384 |
Ref: [Effect of hypoxia on production and secretion of matrix metalloproteinases in tumor cells]. PMID: 15694029 Ref: TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo. PMID: 15910719 |
Ref: Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions. PMID: 16340751 Ref: Analysis of the invasion-metastasis mechanism in pancreatic cancer: involvement of plasmin(ogen) cascade proteins in the invasion of pancreatic cancer cells. PMID: 16391791 Ref: Inhibition of metastatic progression of SSTR2 gene transfection mediated by adenovirus in human pancreatic carcinoma cells. PMID: 16711011 Ref: Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer. PMID: 17034997 Ref: Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro. PMID: 17054436 Ref: Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis. PMID: 17120744 Ref: Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer. PMID: 17377415 Ref: [Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro]. PMID: 17533737 |
Ref: Combination therapy of human pancreatic cancer implanted in nude mice by oral fluoropyrimidine anticancer agent (S-1) with interferon-alpha. PMID: 16699793 Ref: NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo. PMID: 17140727 Ref: Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells. PMID: 17224648 Ref: Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay. PMID: 17227797 Ref: RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells. PMID: 17459060 Ref: Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis. PMID: 17545513 Ref: Action of antiproteases on pancreatic cancer cells. PMID: 17625304 Ref: Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells. PMID: 17804744 |
Ref: EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer. PMID: 17981559 Ref: CXCL14 expression and potential function in pancreatic cancer. PMID: 18054154 Ref: Gamma-irradiation enhances RECK protein levels in Panc-1 pancreatic cancer cells. PMID: 18319621 Ref: [Effect of RNAi-mediated STAT3 gene inhibition on metastasis of human pancreatic cancer cells]. PMID: 19035205 |
Ref: Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2. PMID: 19056927 Ref: Mutational profiling of cancer candidate genes in glioblastoma, melanoma and pancreatic carcinoma reveals a snapshot of their genomic landscapes. PMID: 19058223 Ref: EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2. PMID: 19116140 Ref: Low-level expression of Smad7 correlates with lymph node metastasis and poor prognosis in patients with pancreatic cancer. PMID: 19165547 Ref: Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. PMID: 19266599 Ref: Role of fibrillar Tenascin-C in metastatic pancreatic cancer. PMID: 19287959 Ref: MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance. PMID: 19435867 Ref: Depleting MEKK1 expression inhibits the ability of invasion and migration of human pancreatic cancer cells. PMID: 19513748 Ref: [Effect of icogenin on and its mechanism in anti-metastasis of pancreatic cancer BxPC3 cells]. PMID: 19618718 Ref: Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion. PMID: 19673016 Ref: Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol. PMID: 19724861 |
Ref: PKC Delta (PKCdelta) promotes tumoral progression of human ductal pancreatic cancer. PMID: 19924022 Ref: ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts. PMID: 20023433 Ref: Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells. PMID: 20031158 Ref: Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2. PMID: 20153729 Ref: beta2-adrenergic antagonists suppress pancreatic cancer cell invasion by inhibiting CREB, NFkappaB and AP-1. PMID: 20424515 Ref: Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro. PMID: 20482858 Ref: Lentivirus-mediated reversion-inducing cysteine-rich protein with Kazal motifs gene transfer suppresses pancreatic cancer invasion in vitro. PMID: 20635007 Ref: Ukrain affects pancreas cancer cell phenotype in vitro by targeting MMP-9 and intra-/extracellular SPARC expression. PMID: 20975318 Ref: Effects of lorglumide on growth and invasion of human pancreatic cancer cell line Mia PaCa-2 in vitro through the cholecystokinin-cholecystokinin-1 receptor pathway. PMID: 24688146 |
Ref: X-ray irradiation and Rho-kinase inhibitor additively induce invasiveness of the cells of the pancreatic cancer line, MIAPaCa-2, which exhibits mesenchymal and amoeboid motility. PMID: 21214671 Ref: TGF-beta1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-kappaB/IL-6/MMP-2. PMID: 21219858 Ref: The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. PMID: 21339745 Ref: Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of beta-catenin. PMID: 21448903 Ref: RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation. PMID: 21470770 Ref: STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo. PMID: 21479358 Ref: EGCG downregulates IL-1RI expression and suppresses IL-1-induced tumorigenic factors in human pancreatic adenocarcinoma cells. PMID: 21787753 Ref: Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases. PMID: 21989104 Ref: Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3. PMID: 22016776 |
Ref: Qingyihuaji formula inhibits progress of liver metastases from advanced pancreatic cancer xenograft by targeting to decrease expression of Cyr61 and VEGF. PMID: 21382954 Ref: Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer. PMID: 21954965 Ref: Grape-seed procyanidins inhibit the in vitro growth and invasion of pancreatic carcinoma cells. PMID: 22015975 Ref: Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice. PMID: 22234980 Ref: Effects and mechanism of integrin-beta1 gene expression inhibited by shRNA in invasion of pancreatic carcinoma PANC-1 cells. PMID: 22353524 Ref: CD147 silencing via RNA interference reduces tumor cell invasion, metastasis and increases chemosensitivity in pancreatic cancer cells. PMID: 22427101 Ref: (-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357. PMID: 22497997 Ref: Selection of peptide inhibitor to matrix metalloproteinase-2 using phage display and its effects on pancreatic cancer cell lines PANC-1 and CFPAC-1. PMID: 22606046 Ref: BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK. PMID: 22652796 Ref: The antitumor activity of recombinant antitumor antiviral protein and the associated molecular mechanism in pancreatic tumor cells. PMID: 22783925 Ref: Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis. PMID: 22876305 Ref: The effects of genistein on transforming growth factor-beta1-induced invasion and metastasis in human pancreatic cancer cell line Panc-1 in vitro. PMID: 22884073 Ref: Neurotrophic artemin promotes motility and invasiveness of MIA PaCa-2 pancreatic cancer cells. PMID: 22901124 Ref: Metalloproteinase 2 and 9 activity in the development of pancreatic cancer. PMID: 22985699 Ref: S100A4 siRNA inhibits human pancreatic cancer cell invasion in vitro. PMID: 23026527 Ref: miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway. PMID: 23070684 Ref: Naringenin decreases invasiveness and metastasis by inhibiting TGF-beta-induced epithelial to mesenchymal transition in pancreatic cancer cells. PMID: 23300530 Ref: Microenvironment elements involved in the development of pancreatic cancer tumor. PMID: 23304126 Ref: Concentrations and activities of metalloproteinases 2 and 9 and their inhibitors (TIMPS) in chronic pancreatitis and pancreatic adenocarcinoma. PMID: 23388475 |
Ref: Knockdown of angiopoietin-2 suppresses metastasis in human pancreatic carcinoma by reduced matrix metalloproteinase-2. PMID: 22457202 Ref: Association of single nucleotide polymorphisms of beta2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma. PMID: 22817959 Ref: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. PMID: 22971992 Ref: (-)-Epigallocatechin 3-gallate inhibits invasion by inducing the expression of Raf kinase inhibitor protein in AsPC1 human pancreatic adenocarcinoma cells through the modulation of histone deacetylase activity. PMID: 23135610 Ref: Interaction of the sympathetic nerve with pancreatic cancer cells promotes perineural invasion through the activation of STAT3 signaling. PMID: 23288783 Ref: Neurotransmitter substance P mediates pancreatic cancer perineural invasion via NK-1R in cancer cells. PMID: 23345604 Ref: Aberrant glycogen synthase kinase 3beta is involved in pancreatic cancer cell invasion and resistance to therapy. PMID: 23408967 Ref: Induction of pancreatic cancer cell apoptosis, invasion, migration, and enhancement of chemotherapy sensitivity of gemcitabine, 5-FU, and oxaliplatin by hnRNP A2/B1 siRNA. PMID: 23525071 Ref: Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells. PMID: 23538603 Ref: Concentration of gelatinases and their tissue inhibitors in pancreatic inflammatory and neoplastic tumors and their influence on the early postoperative course. PMID: 23585206 Ref: Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice. PMID: 23684930 Ref: SDF-1alpha upregulation of MMP-2 is mediated by p38 MAPK signaling in pancreatic cancer cell lines. PMID: 23712777 Ref: beta2-AR-HIF-1alpha: a novel regulatory axis for stress-induced pancreatic tumor growth and angiogenesis. PMID: 23745588 Ref: M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway. PMID: 23752129 Ref: The estimation of metaloproteinases and their inhibitors blood levels in patients with pancreatic tumors. PMID: 23768069 Ref: miR-146b-5p inhibits glioma migration and invasion by targeting MMP16. PMID: 23796692 Ref: alpha-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells. PMID: 23833675 Ref: Spiclomazine induces apoptosis associated with the suppression of cell viability, migration and invasion in pancreatic carcinoma cells. PMID: 23840452 Ref: WNT5A/JNK signaling regulates pancreatic cancer cells migration by Phosphorylating Paxillin. PMID: 23890137 Ref: Prognostic significance of extracellular matrix degrading enzymes-cathepsin L and matrix metalloproteases-2 [MMP-2] in human pancreatic cancer. PMID: 23915070 Ref: Correlation between B7-H3 expression and matrix metalloproteinases 2 expression in pancreatic cancer. PMID: 23947693 Ref: Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-kappaB pathway. PMID: 23992306 Ref: Indometacin ameliorates high glucose-induced proliferation and invasion via modulation of e-cadherin in pancreatic cancer cells. PMID: 23992308 Ref: HIF1 contributes to hypoxia-induced pancreatic cancer cells invasion via promoting QSOX1 expression. PMID: 24008827 Ref: CXCL12-CXCR4 promotes proliferation and invasion of pancreatic cancer cells. PMID: 24175834 Ref: Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas. PMID: 24354864 |
Ref: The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma. PMID: 24022664 Ref: Antitumor efficacy of alpha-solanine against pancreatic cancer in vitro and in vivo. PMID: 24505326 Ref: Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells. PMID: 24511528 Ref: Pancreatic satellite cells derived galectin-1 increase the progression and less survival of pancreatic ductal adenocarcinoma. PMID: 24595374 Ref: ZIP4, a novel determinant of tumor invasion in hepatocellular carcinoma, contributes to tumor recurrence after liver transplantation. PMID: 24643086 Ref: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways. PMID: 24694877 Ref: LRH1 promotes pancreatic cancer metastasis. PMID: 24769073 Ref: Depletion of RhoGDI2 expression inhibits the ability of invasion and migration in pancreatic carcinoma. PMID: 24788627 Ref: alpha-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway. PMID: 24812621 Ref: Matrix metalloproteinase-14 is a mechanically regulated activator of secreted MMPs and invasion. PMID: 24878529 Ref: Involvement of ephrin receptor A4 in pancreatic cancer cell motility and invasion. PMID: 24932309 Ref: Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VEcadherin/EphA2/MMP9/MMP2 expression. PMID: 24938458 Ref: Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells. PMID: 24949471 Ref: Knockdown of OCT4 suppresses the growth and invasion of pancreatic cancer cells through inhibition of the AKT pathway. PMID: 25017645 Ref: Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition. PMID: 25017900 Ref: Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from Kras(G12D) mice. PMID: 25050737 Ref: Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies. PMID: 25137018 Ref: The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells. PMID: 25149065 Ref: Elongation factor-2 kinase regulates TG2/beta1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion. PMID: 25215932 Ref: Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro. PMID: 25260978 Ref: Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells. PMID: 25356049 Ref: Interfacing polymeric scaffolds with primary pancreatic ductal adenocarcinoma cells to develop 3D cancer models. PMID: 25482337 Ref: Huachansu injection inhibits metastasis of pancreatic cancer in mice model of human tumor xenograft. PMID: 25496480 Ref: Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line. PMID: 25550789 |
Ref: CXCR4 promotes GSK3beta expression in pancreatic cancer cells via the Akt pathway. PMID: 25145299 Ref: GRP78 promotes the invasion of pancreatic cancer cells by FAK and JNK. PMID: 25218495 Ref: CRKL protein overexpression enhances cell proliferation and invasion in pancreatic cancer. PMID: 25318601 Ref: Ratiometric activatable cell-penetrating peptides label pancreatic cancer, enabling fluorescence-guided surgery, which reduces metastases and recurrence in orthotopic mouse models. PMID: 25319581 Ref: Protease-activated receptor 2 agonist increases cell proliferation and invasion of human pancreatic cancer cells. PMID: 25452809 Ref: MMI-166, a selective matrix metalloproteinase inhibitor, promotes apoptosis in human pancreatic cancer. PMID: 25471789 Ref: KML001 enhances anticancer activity of gemcitabine against pancreatic cancer cells. PMID: 25550550 Ref: Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway. PMID: 25557170 Ref: Correlation and prognostic significance of MMP-2 and TFPI-2 differential expression in pancreatic carcinoma. PMID: 25755762 Ref: miR-29c suppresses pancreatic cancer liver metastasis in an orthotopic implantation model in nude mice and affects survival in pancreatic cancer patients. PMID: 25863127 Ref: miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases. PMID: 25883224 Ref: Molecular mechanism of local drug delivery with Paclitaxel-eluting membranes in biliary and pancreatic cancer: new application for an old drug. PMID: 25983747 Ref: Promotion of Metastasis-associated Gene Expression in Survived PANC-1 Cells Following Trichostatin A Treatment. PMID: 25991546 Ref: Gd-Metallofullerenol Nanomaterial Suppresses Pancreatic Cancer Metastasis by Inhibiting the Interaction of Histone Deacetylase 1 and Metastasis-Associated Protein 1. PMID: 26083726 Ref: Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA. PMID: 26135631 Ref: GSK3beta mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway. PMID: 26213494 Ref: Polyethylenimine-coated SPION exhibits potential intrinsic anti-metastatic properties inhibiting migration and invasion of pancreatic tumor cells. PMID: 26264831 Ref: Peroxisome proliferator-activated receptor-gamma inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN. PMID: 26299428 Ref: Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma. PMID: 26504399 Ref: Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial-mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells. PMID: 26527884 Ref: Trametinib and dactolisib but not regorafenib exert antiproliferative effects on rat pancreatic stellate cells. PMID: 26663013 Ref: Increased matrix metalloproteinase-2 expression and reduced tissue factor pathway inhibitor-2 expression correlate with angiogenesis and early postoperative recurrence of pancreatic carcinoma. PMID: 26807187 Ref: Role of sphingosine 1-phosphate in human pancreatic cancer cells proliferation and migration. PMID: 26884951 |
Ref: Paracrine tumor signaling induces transdifferentiation of surrounding fibroblasts. PMID: 26467073 Ref: Ferulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro. PMID: 26516023 Ref: The effect of PI3K inhibitor LY294002 and gemcitabine hydrochloride combined with ionizing radiation on the formation of vasculogenic mimicry of Panc-1 cells in vitro and in vivo. PMID: 26639237 Ref: Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer. PMID: 26649143 Ref: Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer. PMID: 26655998 Ref: Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels. PMID: 26692441 Ref: Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway. PMID: 26707376 Ref: An MMP-2 Responsive Liposome Integrating Antifibrosis and Chemotherapeutic Drugs for Enhanced Drug Perfusion and Efficacy in Pancreatic Cancer. PMID: 26759926 Ref: NS-398 promotes pancreatic cancer cell invasion by CD147 and MMP-2 via the activation of P38. PMID: 26782265 Ref: Secretome protein signature of human pancreatic cancer stem-like cells. PMID: 26850699 Ref: HIC1 attenuates invasion and metastasis by inhibiting the IL-6/STAT3 signalling pathway in human pancreatic cancer. PMID: 27085461 Ref: Investigation of juglone effects on metastasis and angiogenesis in pancreatic cancer cells. PMID: 27155528 Ref: Celecoxib suppresses fibroblast growth factor-2 expression in pancreatic ductal adenocarcinoma PANC-1 cells. PMID: 27430377 Ref: Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells. PMID: 27471397 Ref: Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-kappaB pathway. PMID: 27572503 Ref: Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway. PMID: 27698853 Ref: C60(OH)22: a potential histone deacetylase inhibitor with anti-angiogenic activity. PMID: 27714131 |
Ref: Expression of Matrix Metalloproteinases-2/-9 is Associated With Microvessel Density in Pancreatic Cancer. PMID: 26866436 Ref: Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers. PMID: 27996162 Ref: Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP-TEAD complex. PMID: 28002618 Ref: Downregulation of the N-myc downstream regulated gene 1 is related to enhanced proliferation, invasion and migration of pancreatic cancer. PMID: 28075464 Ref: Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells. PMID: 28157665 Ref: lncRNA MEG3 had anti-cancer effects to suppress pancreatic cancer activity. PMID: 28320094 Ref: TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. PMID: 28368050 Ref: CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation. PMID: 28388562 Ref: Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression. PMID: 28393239 Ref: A blockade of PD-L1 produced antitumor and antimetastatic effects in an orthotopic mouse pancreatic cancer model via the PI3K/Akt/mTOR signaling pathway. PMID: 28442920 Ref: Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition. PMID: 28475017 Ref: [Effects of RAGE on Cell Proliferation and Tumor Growth in Pancreatic Cancer]. PMID: 28612557 Ref: Long non-coding RNA TUG1 can promote proliferation and migration of pancreatic cancer via EMT pathway. PMID: 28617552 Ref: Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas. PMID: 28627654 Ref: The effects of miRNA-1180 on suppression of pancreatic cancer. PMID: 28670370 Ref: [Stem cell factor enhances invasive ability of BxPC-3 cells via hypoxia-inducible factor 1alpha (HIF-1alpha)]. PMID: 28712397 Ref: Centrosomal protein 55 activates NF-kappaB signalling and promotes pancreatic cancer cells aggressiveness. PMID: 28724890 Ref: Designing Liposomes To Suppress Extracellular Matrix Expression To Enhance Drug Penetration and Pancreatic Tumor Therapy. PMID: 28806504 Ref: Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients. PMID: 29355139 |
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