Primary Site >> Colorectal Cancer
Gene >> MMP2
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Ref: Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. PMID: 2380196 |
Ref: Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia. PMID: 1323219 |
Ref: Expression of MMP-7(PUMP-1) mRNA in human colorectal cancers. PMID: 8514452 |
Ref: Metastasis of human colon tumor cells in vivo: correlation with the overexpression of plasminogen activators and 72 kDa gelatinase. PMID: 7803712 Ref: Gelatinase A (MMP-2) and its mRNA detected in both neoplastic and stromal cells of tumors with different invasive and metastatic properties. PMID: 7981891 Ref: Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. PMID: 7992833 Ref: Autocrine factor enhancing the secretion of M(r) 95,000 gelatinase (matrix metalloproteinase 9) in serum-free medium conditioned with murine metastatic colon carcinoma cells. PMID: 8012988 |
Ref: Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties. PMID: 7896811 |
Ref: Metastatic colorectal cancer cells induce matrix metalloproteinase release by human monocytes. PMID: 8521614 Ref: Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. PMID: 8548762 Ref: Correspondence re: N-B. Liabakk et al., matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res., 56: 190-196, 1966. PMID: 8758934 Ref: Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors. PMID: 8895669 Ref: Antiinvasive effects of Tiazofurin on liver-metastatic human colon carcinoma xenografts. PMID: 9042307 |
Ref: Detection of matrix metalloproteinase activity in human pancreatic cancer. PMID: 9086544 Ref: Characterizing human colorectal carcinomas by proteolytic profile. PMID: 9239513 Ref: Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage. PMID: 9310250 Ref: Inhibitory effects of oleic and docosahexaenoic acids on lung metastasis by colon-carcinoma-26 cells are associated with reduced matrix metalloproteinase-2 and -9 activities. PMID: 9389579 Ref: Increased type IV collagen-degrading activity in metastases originating from primary tumors of the human colon. PMID: 9702942 Ref: Expression and localization of matrix metalloproteinases and tissue inhibitors of metalloproteinases as a prognostic factor in advanced colorectal carcinomas. PMID: 21590124 |
Ref: The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer. PMID: 9468552 Ref: Short chain fatty acids inhibit human (SW1116) colon cancer cell invasion by reducing urokinase plasminogen activator activity and stimulating TIMP-1 and TIMP-2 activities, rather than via MMP modulation. PMID: 9695737 Ref: Loss of epithelial differentiation markers and acquisition of vimentin expression after xenograft with laminin-1 enhance migratory and invasive abilities of human colon cancer cells LoVo C5. PMID: 9697308 Ref: In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma. PMID: 9721885 Ref: [Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]. PMID: 9742524 Ref: Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy. PMID: 9836483 |
Ref: Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer. PMID: 10223763 Ref: Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis. PMID: 10334190 Ref: The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis. PMID: 10425288 Ref: Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer. PMID: 10432005 Ref: Proteolysis in human breast and colorectal cancer. PMID: 10496354 Ref: Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo. PMID: 10545021 Ref: Proteolysis in colorectal cancer. PMID: 10621835 Ref: Involvement of TNF-alpha in enhancement of invasion and metastasis of colon 26-L5 carcinoma cells in mice by social isolation stress. PMID: 10850887 Ref: The gelatinases, their activators and inhibitors in the progression of colorectal cancer. PMID: 23577842 |
Ref: The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer. PMID: 10638999 Ref: Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. PMID: 10662785 Ref: Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer. PMID: 10706135 Ref: Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer. PMID: 10732772 Ref: Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent manner. PMID: 10747288 Ref: Cinnamamide, an antitumor agent with low cytotoxicity acting on matrix metalloproteinase. PMID: 10757563 Ref: Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer. PMID: 10810401 Ref: Ito cell morphology, alpha-smooth muscle actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors. PMID: 10841310 Ref: Lithocholic acid and sulphated lithocholic acid differ in the ability to promote matrix metalloproteinase secretion in the human colon cancer cell line CaCo-2. PMID: 10861227 Ref: Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cells in non-contact Co-cultures. PMID: 10861469 Ref: Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma. PMID: 10901373 Ref: Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor. PMID: 10910039 Ref: A functional proteomics screen of proteases in colorectal carcinoma. PMID: 10952024 Ref: Matrix metalloproteinases, their tissue inhibitors and colorectal cancer staging. PMID: 10971431 Ref: Overexpression of the csk gene suppresses tumor metastasis in vivo. PMID: 11054667 Ref: Establishment and characterization of two new rectal neuroendocrine cell carcinoma cell lines. PMID: 11070410 Ref: Prognostic significance of matrix metalloproteinase expression in colorectal carcinomas. PMID: 11212843 Ref: [Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]. PMID: 11832095 |
Ref: Inhibition of tumor cell invasiveness by chemically modified tetracyclines. PMID: 11172681 Ref: Clinicopathological significance of fibrotic capsule formation around liver metastasis from colorectal cancer. PMID: 11260865 Ref: AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice. PMID: 11268284 Ref: nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression. PMID: 11337376 Ref: Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase. PMID: 11401321 Ref: Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas. PMID: 11459286 Ref: Serous tumors of low malignant potential of the ovary-molecular pathology: part 2. PMID: 11469685 Ref: Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer. PMID: 11594775 Ref: Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis. PMID: 11691582 Ref: Activity and cellular origin of gelatinases in patients with colon and rectal carcinoma differential activity of matrix metalloproteinase-9. PMID: 11745204 Ref: Interleukin-15 expression is associated with malignant potential in colon cancer cells. PMID: 11752902 Ref: Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa. PMID: 11786732 Ref: Genetic modification of cell lines to enhance their metastatic capability. PMID: 21340844 |
Ref: Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166. PMID: 11734335 Ref: Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel. PMID: 11857296 Ref: Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck. PMID: 11867199 Ref: Measuring gelatinase activity in colorectal cancer. PMID: 11869009 Ref: Increased membrane type 1 matrix metalloproteinase expression from adenoma to colon cancer: a possible mechanism of neoplastic progression. PMID: 12006939 Ref: Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer. PMID: 12085179 Ref: Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer. PMID: 12124799 Ref: Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas. PMID: 12173379 Ref: Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium. PMID: 12184536 Ref: Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice. PMID: 12235002 |
Ref: Serum markers of matrix turnover as predictors for the evolution of colorectal cancer metastasis under chemotherapy. PMID: 12698191 Ref: In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin. PMID: 12754293 Ref: Overexpression of the thrombospondin 2 (TSP2) gene modulated by the matrix metalloproteinase family expression and production in human colon carcinoma cell line. PMID: 12792739 Ref: Profiles of matrix metalloproteinases and their tissue inhibitors in intraperitoneal drainage fluid: relationship to wound healing. PMID: 12846914 Ref: Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients. PMID: 14520690 Ref: Detection of type IV collagenase activity in malignant ascites. PMID: 14606104 Ref: Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis. PMID: 14648736 Ref: Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells. PMID: 14666611 Ref: Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas. PMID: 14666620 |
Ref: Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity. PMID: 14556651 Ref: Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. PMID: 14760389 Ref: Circulating matrix metalloproteinase-9 is transiently elevated after colorectal surgery. PMID: 14986032 Ref: A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer. PMID: 15041713 Ref: Doxycycline inhibits cell proliferation and invasive potential: combination therapy with cyclooxygenase-2 inhibitor in human colorectal cancer cells. PMID: 15085079 Ref: (-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis. PMID: 15172120 Ref: Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel. PMID: 15185339 Ref: Prognostic significance of matrix metalloproteinase-2, cathepsin D, and tenascin-C expression in colorectal carcinoma. PMID: 15239346 Ref: The membrane-anchored matrix metalloproteinase (MMP) regulator RECK in combination with MMP-9 serves as an informative prognostic indicator for colorectal cancer. PMID: 15328199 Ref: Contributory role of 5-lipoxygenase and its association with angiogenesis in the promotion of inflammation-associated colonic tumorigenesis by cigarette smoking. PMID: 15363593 Ref: A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer. PMID: 15485653 Ref: Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization. PMID: 15519565 Ref: The role of gelatinases in colorectal cancer progression and metastasis. PMID: 15588763 Ref: Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers. PMID: 15623598 Ref: Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers. PMID: 15623631 |
Ref: Clinical relevance of MMP-9, MMP-2, TIMP-1 and TIMP-2 in colorectal cancer. PMID: 15583811 Ref: Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer. PMID: 15592677 Ref: Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. PMID: 15661802 Ref: Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells. PMID: 15713899 Ref: Expression of cyclooxygenase-2 in colorectal cancer and its clinical significance. PMID: 15754389 Ref: Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases. PMID: 15869913 Ref: Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients. PMID: 15882437 Ref: Plasma levels of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 correlate with disease stage and survival in colorectal cancer patients. PMID: 15906450 Ref: Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis. PMID: 15918187 Ref: Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors. PMID: 15918191 Ref: [Role of tissue factor in the invasion of cultured human colon carcinoma cells and its correlation with matrix metalloproteinases]. PMID: 15968316 Ref: [The expression of matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinases (TIMPs) and angiogenesis in relation to the depth of tumor invasion and lymph node metastasis in submucosally invasive colorectal carcinoma]. PMID: 15973074 Ref: Effects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cells in vitro. PMID: 15991286 Ref: Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells. PMID: 16001424 Ref: Plasma gelatinase activity does not reflect disease activity after operation for colorectal cancer. PMID: 16015042 Ref: Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. PMID: 16052675 Ref: Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples. PMID: 16101153 Ref: A mechanistic study of colon cancer growth promoted by cigarette smoke extract. PMID: 16125168 Ref: Pericellular activation of proMMP-7 (promatrilysin-1) through interaction with CD151. PMID: 16200075 Ref: Effect of a nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester on invasion of human colorectal cancer cell line SL-174T. PMID: 16419170 |
Ref: Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer. PMID: 16046057 Ref: Platelet aggregation-induced by caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate. PMID: 16424148 Ref: [The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]. PMID: 16456793 Ref: Gefitinib decreases the synthesis of matrix metalloproteinase and the adhesion to extracellular matrix proteins of colon cancer cells. PMID: 16475688 Ref: [Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]. PMID: 16555154 Ref: Gastrin enhances the angiogenic potential of endothelial cells via modulation of heparin-binding epidermal-like growth factor. PMID: 16585174 Ref: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. PMID: 16619535 Ref: Circulating gelatinases and tissue inhibitor of metalloproteinase-1 in colorectal cancer metastatic liver disease. PMID: 16650961 Ref: Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. PMID: 16691544 Ref: Matrix metalloproteinase (MMP) -1, -2, -3 and -9 promoter polymorphisms in colorectal cancer. PMID: 16739355 Ref: Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue. PMID: 16752205 Ref: Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer. PMID: 16916471 Ref: Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation. PMID: 16934296 Ref: Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence. PMID: 16973348 Ref: Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential? PMID: 17075343 Ref: Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice. PMID: 17151446 Ref: Effect of DPC4 gene on invasion and metastasis of colorectal carcinoma cells. PMID: 17151782 Ref: [Erythromycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs]. PMID: 17313833 |
Ref: Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer. PMID: 16896992 Ref: Matrix metalloproteinase-9 expression correlated with tumor response in patients with locally advanced rectal cancer undergoing preoperative chemoradiotherapy. PMID: 17071013 Ref: Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation. PMID: 17109104 Ref: Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway. PMID: 17283136 Ref: The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer. PMID: 17311017 Ref: MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells. PMID: 17332939 Ref: Antitumor effects of Nafamostat mesilate on head and neck squamous cell carcinoma. PMID: 17337140 Ref: Effects of two conventional preoperative radiation schedules on anastomotic healing in the rat colon. PMID: 17337891 Ref: Beneficial influence of microsatellite instability on gelatinase-tissue inhibitors of metalloproteinase balance in colorectal cancer. PMID: 17348445 Ref: SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. PMID: 17369830 Ref: Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer. PMID: 17455256 Ref: Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels. PMID: 17516864 Ref: Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese. PMID: 17546628 Ref: A novel in vitro model of lymphatic metastasis from colorectal cancer. PMID: 17640671 Ref: Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples. PMID: 17649785 Ref: [Short hairpin RNA-mediated survivin gene silencing inhibits invasion and metastasis of human colon carcinoma cell line SW480 in vitro]. PMID: 17666323 Ref: Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer. PMID: 17669467 Ref: Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation. PMID: 17721919 Ref: Inhibitory effects of retinoic acid and IIF on growth, migration and invasiveness in the U87MG human glioblastoma cell line. PMID: 17786368 Ref: ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. PMID: 17876296 Ref: Identification of gene signatures for invasive colorectal tumor cells. PMID: 17936523 Ref: Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion. PMID: 17982677 Ref: The value and correlation between PRL-3 expression and matrix metalloproteinase activity and expression in human gliomas. PMID: 18021371 Ref: Inhibition of proinflammatory cytokine-induced invasiveness of HT-29 cells by chitosan oligosaccharide. PMID: 18167453 Ref: [Expression of MMP-2, HIF-1alpha and VEGF in colon adenoma and colon cancer]. PMID: 18172354 Ref: Prognostic significance of expression of matrix metalloproteinase in colorectal adenocarcinomas and their metastases. PMID: 18214299 Ref: Colorectal cancer or colon and rectal cancer? Clinicopathological comparison between colonic and rectal carcinomas. PMID: 18334831 |
Ref: Functional proteomics study reveals that N-Acetylglucosaminyltransferase V reinforces the invasive/metastatic potential of colon cancer through aberrant glycosylation on tissue inhibitor of metalloproteinase-1. PMID: 17878270 Ref: Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2. PMID: 18086515 Ref: Cyclooxygenase-2 inhibition prevents migration of colorectal cancer cells to extracellular matrix by down-regulation of matrix metalloproteinase-2 expression. PMID: 18228100 Ref: Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy. PMID: 18376229 Ref: Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro. PMID: 18416455 Ref: Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from co PMID: 18425389 Ref: Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer. PMID: 18438340 Ref: MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not. PMID: 18506186 Ref: Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts. PMID: 18508606 Ref: Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model. PMID: 18583324 Ref: Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas. PMID: 18619649 Ref: Invasion front-specific overexpression of tissue inhibitor of metalloproteinase-1 in liver metastases from colorectal cancer. PMID: 18630499 Ref: Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1 alpha expression in colon carcinoma cells. PMID: 18674879 Ref: VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis. PMID: 18691882 Ref: [Expression of MMP-2, MMP-9 and collagen type IV and their relationship in colorectal carcinomas]. PMID: 18782525 Ref: Resistin in human colorectal cancer: increased expression independently of resistin promoter -420C > G genotype. PMID: 18798067 Ref: [Effects of phosphatase of regenerating liver cell-3 gene silence by RNA interference on the expression of matrix metalloproteinases-2,-9 in human colon cancer cells]. PMID: 18803055 Ref: Immunohistochemically detected high expression of matrix metalloproteinase-2 as predictor of poor prognosis in Duke's B colon cancer. PMID: 18925697 Ref: Identification of amino acid residues of matrix metalloproteinase-7 essential for binding to cholesterol sulfate. PMID: 18955490 Ref: Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells. PMID: 19020709 Ref: Suppression of invasive properties of colorectal carcinoma SW480 cells by 15-hydroxyprostaglandin dehydrogenase gene. PMID: 19034772 Ref: Matrix metalloproteinases 2, 3, 13 and their type 2 tissue inhibitor in tumors and plasma of patients with colorectal cancer. PMID: 19039945 |
Ref: Inhibition of cell proliferation and invasion in a human colon cancer cell line by 5-aminosalicylic acid. PMID: 18976971 Ref: Mutational profiling of cancer candidate genes in glioblastoma, melanoma and pancreatic carcinoma reveals a snapshot of their genomic landscapes. PMID: 19058223 Ref: Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine. PMID: 19159630 Ref: Differences in the gene expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in primary colorectal tumors and their synchronous liver metastases. PMID: 19331134 Ref: Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expression. PMID: 19426720 Ref: Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer. PMID: 19445018 Ref: Poly(ADP-ribose) polymerase inhibition down-regulates expression of metastasis-related genes in CT26 colon carcinoma cells. PMID: 19468250 Ref: Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects. PMID: 19507256 Ref: Key enzymes of the extracellular matrix in colorectal cancer. PMID: 19529860 Ref: Active MMP-2 effectively identifies the presence of colorectal cancer. PMID: 19551856 Ref: Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness. PMID: 19603013 Ref: [Effects of allicin on invasion and metastasis of colon cancer LoVo cell line in vitro]. PMID: 19671326 Ref: Distinct high-profile methylated genes in colorectal cancer. PMID: 19750230 Ref: Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells. PMID: 19820721 Ref: PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin beta1-ERK1/2 and-MMP2 signaling. PMID: 19930715 |
Ref: Effect of arginine on angiogenesis induced by human colon cancer: in vitro and in vivo studies. PMID: 19447018 Ref: The tumor-associated antigen 90K/Mac-2-binding protein secreted by human colon carcinoma cells enhances extracellular levels of promatrilysin and is a novel substrate of matrix metalloproteinases-2, -7 (matrilysin) and -9: Implications of proteolytic clea PMID: 19665518 Ref: Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells. PMID: 19947919 Ref: Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1. PMID: 20017136 Ref: Characterization of a profile of the anthocyanins isolated from Vitis coignetiae Pulliat and their anti-invasive activity on HT-29 human colon cancer cells. PMID: 20060025 Ref: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. PMID: 20136087 Ref: Growth and invasion of sporadic colorectal adenocarcinomas in terms of genetic change. PMID: 20191032 Ref: Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. PMID: 20360625 Ref: Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid. PMID: 20429953 Ref: Effects of dietary beef and chicken with and without high amylose maize starch on blood malondialdehyde, interleukins, IGF-I, insulin, leptin, MMP-2, and TIMP-2 concentrations in rats. PMID: 20432166 Ref: Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis. PMID: 20442318 Ref: Anti-invasion effect of rosmarinic acid via the extracellular signal-regulated kinase and oxidation-reduction pathway in Ls174-T cells. PMID: 20506543 Ref: Thymosin beta4 regulates migration of colon cancer cells by a pathway involving interaction with Ku80. PMID: 20536451 Ref: Andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activity. PMID: 20539971 Ref: Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model. PMID: 20616008 Ref: Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression. PMID: 20654727 Ref: Intratumoral macrophage counts correlate with tumor progression in colorectal cancer. PMID: 20740582 Ref: Raf kinase inhibitor protein suppresses nuclear factor-kappaB-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression. PMID: 20855151 Ref: Phenethyl isothiocyanate inhibited tumor migration and invasion via suppressing multiple signal transduction pathways in human colon cancer HT29 cells. PMID: 20863062 Ref: GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells. PMID: 20888181 Ref: Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells. PMID: 20926374 Ref: Anti-carcinogenic properties of curcumin on colorectal cancer. PMID: 21160593 Ref: Evaluation of the expression of metalloproteinases 2 and 9 and their tissue inhibitors in colon cancer cells treated with phytic acid. PMID: 21229878 Ref: Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients. PMID: 21478099 Ref: [State of the liver antioxidant system and content of matrix metalloproteinase-2 of the large intestine under the effect of maleimide derivative in experimental colorectal carcinogenesis in rats]. PMID: 21516719 Ref: Extrahepatic synthesis of coagulation factor VII by colorectal cancer cells promotes tumor invasion and metastasis. PMID: 22166631 |
Ref: Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2. PMID: 19876598 Ref: Role of gelatinases (matrix metalloproteinases 2 and 9), vascular endothelial growth factor and endostatin on clinicopathological behaviour of rectal cancer. PMID: 19888958 Ref: Up-regulation of the novel proinflammatory adipokines lipocalin-2, chitinase-3 like-1 and osteopontin as well as angiogenic-related factors in visceral adipose tissue of patients with colon cancer. PMID: 20961744 Ref: Anti-interleukin-6 receptor antibody inhibits the progression in human colon carcinoma cells. PMID: 21114487 Ref: Peptides from Lactobacillus hydrolysates of bovine milk caseins inhibit prolyl-peptidases of human colon cells. PMID: 21126072 Ref: Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma. PMID: 21170925 Ref: Matrix metalloproteinase-9 is a prognostic marker to predict survival of patients who underwent surgery due to rectal carcinoma. PMID: 21212604 Ref: Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers. PMID: 21237495 Ref: Clinical characteristics of TIMP2, MMP2, and MMP9 gene polymorphisms in colorectal cancer. PMID: 21261731 Ref: Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy. PMID: 21281787 Ref: Do young patients with colorectal cancer have a poorer prognosis than old patients? PMID: 21316708 Ref: The potential of osteopontin as a therapeutic target for human colorectal cancer. PMID: 21318445 Ref: p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells. PMID: 21353507 Ref: Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity. PMID: 21377450 Ref: Associations between single nucleotide polymorphisms of MMP2, VEGF, and HIF1A genes and the risk of developing colorectal cancer. PMID: 21378341 Ref: Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients. PMID: 21393869 Ref: Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo. PMID: 21409599 Ref: Substrate optimization and clinical validation of reporter peptides for MS-based protease profiling in serum specimens: a new approach for diagnosis of malignant disease. PMID: 21503574 Ref: Absence of MMP2 expression correlates with poor clinical outcomes in rectal cancer, and is distinct from MMP1-related outcomes in colon cancer. 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PMID: 26790446 Ref: Eriocalyxin B blocks human SW1116 colon cancer cell proliferation, migration, invasion, cell cycle progression and angiogenesis via the JAK2/STAT3 signaling pathway. PMID: 26795301 Ref: High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma. PMID: 26814712 Ref: Cucurbitacin B Enhances the Anticancer Effect of Imatinib Mesylate Through Inhibition of MMP-2 Expression in MCF-7 and SW480 Tumor Cell Lines. PMID: 26863882 Ref: Baicalein inhibits the migration and invasion of colorectal cancer cells via suppression of the AKT signaling pathway. PMID: 26870267 Ref: Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines. PMID: 26896068 Ref: Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/beta-catenin signaling. PMID: 26910283 Ref: Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis. PMID: 26929650 Ref: Relationship of serum polyunsaturated fatty acids with cytokines in colorectal cancer. PMID: 26937140 Ref: Down-regulation of osteoprotegerin expression as a novel biomarker for colorectal carcinoma. PMID: 26942563 Ref: MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer. PMID: 26983891 Ref: Role of cancer stem cells in racial disparity in colorectal cancer. PMID: 26990997 Ref: [Expression and clinical significance of kisspeptin-1, matrix metalloproteinase-2 and vascular endothelial growth factor in tissue of colon cancer]. PMID: 27005549 Ref: FOXM1 promotes invasion and migration of colorectal cancer cells partially dependent on HSPA5 transactivation. PMID: 27034162 Ref: Knockdown of LI-cadherin alters expression of matrix metalloproteinase-2 and -9 and galectin-3. PMID: 27035870 Ref: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression. PMID: 27098148 Ref: Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway. PMID: 27121420 Ref: The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer. PMID: 27145365 Ref: An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells. PMID: 27163855 Ref: miR-375 inhibits the invasion and metastasis of colorectal cancer via targeting SP1 and regulating EMT-associated genes. PMID: 27222350 Ref: Matrix metalloproteinase (MMP) -2, -7 and -9 promoter polymorphisms in colorectal cancer in ethnic Kashmiri population - A case-control study and a mini review. 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PMID: 27401218 Ref: Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and beta-catenin signaling pathways. PMID: 27422337 Ref: RUNX3 inhibits the metastasis and angiogenesis of colorectal cancer. PMID: 27633042 Ref: Rab11 collaborates E-cadherin to promote collective cell migration and indicates a poor prognosis in colorectal carcinoma. PMID: 27696383 Ref: 4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl inhibits angiogenesis by suppressing VEGFR2 and Tie2 phosphorylation. PMID: 27698866 Ref: ING4 suppresses tumor angiogenesis and functions as a prognostic marker in human colorectal cancer. PMID: 27806345 Ref: Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma. 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Ref: Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. PMID: 27481098 Ref: SMC1A recruits tumor-associated-fibroblasts (TAFs) and promotes colorectal cancer metastasis. PMID: 27826041 Ref: Genetic disruption of tubulin acetyltransferase, alphaTAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/beta-catenin signaling. PMID: 27836544 Ref: Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells. PMID: 27862857 Ref: Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study. PMID: 27922483 Ref: Targeted Delivery of Interferon Gamma Using a Recombinant Fusion Protein of a Fibrin Clot-Binding Peptide With Interferon Gamma for Cancer Gene Therapy. 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PMID: 28335083 Ref: Reciprocal control of lncRNA-BCAT1 and beta-catenin pathway reveals lncRNA-BCAT1 long non-coding RNA acts as a tumor suppressor in colorectal cancer. PMID: 28416735 Ref: MicroRNA-140-5p inhibits cell proliferation and invasion by regulating VEGFA/MMP2 signaling in glioma. PMID: 28443475 Ref: Anticancer activity of Nelumbo nucifera stamen extract in human colon cancer HCT-116 cells in vitro. PMID: 28454279 Ref: Matrix metalloproteinases in Vietnamese patients with colorectal cancer. PMID: 28454367 Ref: Parthenolide promotes apoptotic cell death and inhibits the migration and invasion of SW620 cells. PMID: 28522946 Ref: Unique insight into microenvironmental changes in colorectal cancer: Ex vivo assessment of matrix metalloprotease-mediated molecular changes in human colorectal tumor tissue and corresponding non-neoplastic adjacent tissue. PMID: 28529592 Ref: Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. PMID: 28549801 Ref: TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways. PMID: 28624785 Ref: Epithelial-mesenchymal transition and cancer stem cell-like phenotype induced by Twist1 contribute to acquired resistance to irinotecan in colon cancer. PMID: 28627611 Ref: Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo. PMID: 28627695 Ref: The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology. PMID: 28634392 Ref: MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling. PMID: 28653875 Ref: Low expression of microRNA-320b correlates with tumorigenesis and unfavorable prognosis in glioma. PMID: 28656255 Ref: Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells. PMID: 28688953 Ref: Proliferation and invasion of ovarian cancer cells are suppressed by knockdown of TRIM11. PMID: 28781653 Ref: Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers. PMID: 28833104 Ref: Prediction of pathological response to neoadjuvant treatment in rectal cancer with a two-protein immunohistochemical score derived from stromal gene-profiling. PMID: 28911071 Ref: Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2. PMID: 28931592 Ref: Ca(2+)/calmodulin-dependent protein kinase II regulates colon cancer proliferation and migration via ERK1/2 and p38 pathways. PMID: 28970726 Ref: The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo. PMID: 29048673 Ref: Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation. PMID: 29113214 Ref: [Expression of LOX in Colorectal Cancer Tissues and Its Relationship with Progress and Prognosis]. PMID: 29130678 Ref: ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells. PMID: 29151941 Ref: Scutellaria barbata D. Don inhibits migration and invasion of colorectal cancer cells via suppression of PI3K/AKT and TGF-beta/Smad signaling pathways. PMID: 29285087 Ref: Role of DDX3 in the pathogenesis of inflammatory bowel disease. PMID: 29383159 Ref: Matrix Metalloproteinase-2 and -9, Lactate, and Malate Dehydrogenase and Lipid Peroxides in Sera of Patients with Colorectal Carcinoma. PMID: 29687772 |
Ref: Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma. PMID: 28600709 Ref: Nicotine increases colon cancer cell migration and invasion through epithelial to mesenchymal transition (EMT): COX-2 involvement. PMID: 29215713 Ref: Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer. PMID: 29260353 Ref: RNA interference-mediated silencing of aquaporin (AQP)-5 hinders angiogenesis of colorectal tumor by suppressing the production of vascular endothelial growth factor. PMID: 29322789 Ref: MicroRNA-466 (miR-466) functions as a tumor suppressor and prognostic factor in colorectal cancer (CRC). PMID: 29338680 Ref: Tea Polysaccharide Prevents Colitis-Associated Carcinogenesis in Mice by Inhibiting the Proliferation and Invasion of Tumor Cells. PMID: 29419740 Ref: MACC1 and HGF are associated with survival in patients with gastric cancer. PMID: 29435059 Ref: Down-regulation of miRNA-320c promotes tumor growth and metastasis and predicts poor prognosis in human glioma. PMID: 29438779 Ref: The clinical significance and biological function of tropomyosin 4 in colon cancer. PMID: 29455030 Ref: The role of miR-766-5p in cell migration and invasion in colorectal cancer. PMID: 29456660 Ref: Rosmarinic Acid Activates AMPK to Inhibit Metastasis of Colorectal Cancer. PMID: 29459827 Ref: Construction of key signal regulatory network in metastatic colorectal cancer. PMID: 29464057 Ref: Dihydroartemisinin inhibits colon cancer cell viability by inducing apoptosis through up-regulation of PPARgamma expression. PMID: 29472793 Ref: Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas. PMID: 29511595 Ref: Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway. PMID: 29519997 Ref: Cellular prion protein and gamma-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch. PMID: 29527422 Ref: Autumn Royal and Ribier Grape Juice Extracts Reduced Viability and Metastatic Potential of Colon Cancer Cells. PMID: 29552079 Ref: The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer. PMID: 29562216 Ref: Genistein inhibits invasion and migration of colon cancer cells by recovering WIF1 expression. PMID: 29568950 Ref: Halogenated Bis(methoxybenzylidene)-4-piperidone Curcuminoids with Improved Anticancer Activity. PMID: 29570947 Ref: Effects of secreted frizzled-related protein 1 on proliferation, migration, invasion, and apoptosis of colorectal cancer cells. PMID: 29610564 Ref: Formononetin inhibits colon carcinoma cell growth and invasion by microRNA149mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways. PMID: 29620230 Ref: Role of matrix metalloproteinases in tumour invasion: immunohistochemistry of peritoneum from peritoneal carcinomatosis. PMID: 29623449 Ref: Long noncoding RNA BC200 regulates cell growth and invasion in colon cancer. PMID: 29625226 Ref: Tea Polysaccharides Inhibit Colitis-Associated Colorectal Cancer via Interleukin-6/STAT3 Pathway. PMID: 29656647 Ref: Peroxiredoxin 1 promoted tumor metastasis and angiogenesis in colorectal cancer. PMID: 29673884 Ref: A supercritical CO2 extract of neem leaf (A. indica) and its bioactive liminoid, nimbolide, suppresses colon cancer in preclinical models by modulating pro-inflammatory pathways. PMID: 29697164 Ref: Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-kappaB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways. PMID: 29731901 Ref: Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells. PMID: 29749478 Ref: Downregulation of RPN2 induces apoptosis and inhibits migration and invasion in colon carcinoma. PMID: 29749494 Ref: Proliferation and invasion of colon cancer cells are suppressed by knockdown of TOP2A. PMID: 29761838 Ref: Angiogenin and the MMP9-TIMP2 axis are up-regulated in proangiogenic, decidual NK-like cells from patients with colorectal cancer. PMID: 29763380 Ref: SERPINA3 Silencing Inhibits the Migration, Invasion, and Liver Metastasis of Colon Cancer Cells. PMID: 29855767 Ref: Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis. PMID: 29867200 Ref: beta3GnT8 Promotes Colorectal Cancer Cells Invasion via CD147/MMP2/Galectin3 Axis. PMID: 29875690 Ref: [Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells]. PMID: 29891445 Ref: Extracellular gamma-synuclein promotes tumor cell motility by activating beta1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion. PMID: 29903032 Ref: The long noncoding RNA BC0209135 inhibits the cell invasion through Wnt/beta-catenin signaling in colorectal cancer. PMID: 29949151 Ref: Wnt6 contributes tumorigenesis and development of colon cancer via its effects on cell proliferation, apoptosis, cell-cycle and migration. PMID: 29963191 Ref: The stress response gene ATF3 is a direct target of the Wnt/beta-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells. PMID: 29966001 Ref: Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. PMID: 29980883 Ref: Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer. PMID: 29997437 Ref: Pin2/TRF1binding protein X1 inhibits colorectal cancer cell migration and invasion in vitro and metastasis in vivo via the nuclear factorkappaB signaling pathway. PMID: 30015978 Ref: Sulforaphane, a Chemopreventive Compound, Inhibits Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Expression in Human HT-29 Colon Cancer Cells. PMID: 30041241 Ref: Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability. PMID: 30056083 Ref: Inositol hexaphosphate limits the migration and the invasiveness of colorectal carcinoma cells in vitro. PMID: 30066850 Ref: Wnt/beta-catenin signaling pathway is involved in regulating the migration by an effective natural compound brucine in LoVo cells. PMID: 30097126 Ref: Antitumor Effects of Umbelliprenin in a Mouse Model of Colorectal Cancer. PMID: 30127820 Ref: Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells. PMID: 30210348 Ref: Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma. PMID: 30228782 Ref: [How to predict the relapse after surgery or radiofrequency of liver metastases of colorectal cancer? Interest of the serum kinetic variation of a matrix metalloproteinase cluster]. PMID: 30243479 Ref: Protective effects of thymoquinone on the healing process of experimental left colonic anastomosis. PMID: 30278931 Ref: Cofilin-1 signaling mediates epithelial-mesenchymal transition by promoting actin cytoskeleton reorganization and cell-cell adhesion regulation in colorectal cancer cells. PMID: 30296500 Ref: Upregulation of HRD1 promotes cell migration and invasion in colon cancer. PMID: 30306455 Ref: Nafamostat Mesilate Enhances the Radiosensitivity and Reduces the Radiation-Induced Invasive Ability of Colorectal Cancer Cells. PMID: 30336548 Ref: Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells. PMID: 30349300 Ref: Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelialmesenchymal transition mediated by the FAK/AKT/MMPs axis. PMID: 30365116 Ref: Galla Rhois water extract inhibits lung metastasis by inducing AMPKmediated apoptosis and suppressing metastatic properties of colorectal cancer cells. PMID: 30365120 Ref: Knockdown of MON1B Exerts Anti-Tumor Effects in Colon Cancer In Vitro. PMID: 30368516 Ref: CRP and LOX-1: a Mechanism for Increasing the Tumorigenic Potential of Colorectal Cancer Carcinoma Cell Line. PMID: 30368730 Ref: Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1alpha nuclear translocation. PMID: 30388517 |