Primary Site >> Colorectal Cancer
Gene >> MMP1
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Ref: Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers. PMID: 7951846 |
Ref: The distribution of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal cancer. PMID: 7551259 Ref: The distribution of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal cancer. PMID: 7780609 Ref: Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties. PMID: 7896811 |
Ref: Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer. PMID: 8597958 Ref: Interleukin 4 inhibits hepatocyte growth factor-induced invasion and migration of colon carcinomas. PMID: 8891890 |
Ref: [Effect on 5'-deoxy-5-fluorouridine (5'-DFUR) of pyrimidine nucleoside phosphorylase (PyNPase), matrix metalloprotease and serum IAP values. Hokuriku Colorectal Cancer Chemotherapy Study Group]. PMID: 9350241 Ref: Expression and localization of matrix metalloproteinases and tissue inhibitors of metalloproteinases as a prognostic factor in advanced colorectal carcinomas. PMID: 21590124 |
Ref: Short chain fatty acids inhibit human (SW1116) colon cancer cell invasion by reducing urokinase plasminogen activator activity and stimulating TIMP-1 and TIMP-2 activities, rather than via MMP modulation. PMID: 9695737 Ref: Effects of fatty acids on liver metastasis of ACL-15 rat colon cancer cells. PMID: 9770727 |
Ref: Matrix metalloproteinase inhibition prevents colon cancer peritoneal carcinomatosis development and prolongs survival in rats. PMID: 10426790 Ref: Proteolysis in colorectal cancer. PMID: 10621835 |
Ref: MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer. PMID: 10794801 Ref: Application of the enrichment approach to identify putative markers of response to 5-fluorouracil therapy in advanced colorectal carcinomas. PMID: 10853033 Ref: A functional proteomics screen of proteases in colorectal carcinoma. PMID: 10952024 Ref: Matrix metalloproteinases, their tissue inhibitors and colorectal cancer staging. PMID: 10971431 Ref: Simultaneous measurement of soluble carcinoembryonic antigen and the tissue inhibitor of metalloproteinase TIMP1 serum levels for use as markers of pre-invasive to invasive colorectal cancer. PMID: 10999465 Ref: Expression of matrix metalloproteinase-1 in human colorectal carcinoma. PMID: 11007031 Ref: [beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma]. PMID: 11217438 |
Ref: Clinicopathological significance of fibrotic capsule formation around liver metastasis from colorectal cancer. PMID: 11260865 Ref: Upregulated expression of angiogenesis genes and down regulation of cell cycle genes in human colorectal cancer tissue determined by cDNA macroarray. PMID: 11299727 Ref: Glycine-extended gastrin promotes the invasiveness of human colon cancer cells. PMID: 11437383 Ref: Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness. PMID: 11489811 |
Ref: Collagen distribution and expression of matrix metalloproteinases 1 and 13 in patients with anastomotic leakage after large-bowel surgery. PMID: 11819107 Ref: Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer. PMID: 12432557 |
Ref: The plasminogen activator and matrix metalloproteinase systems in colorectal cancer: relationship to tumour pathology. PMID: 12706368 Ref: Profiles of matrix metalloproteinases and their tissue inhibitors in intraperitoneal drainage fluid: relationship to wound healing. PMID: 12846914 Ref: Association of ets-related transcriptional factor E1AF expression with tumour progression and overexpression of MMP-1 and matrilysin in human colorectal cancer. PMID: 12898592 Ref: Stromal expression of invasion-promoting, matrix-degrading proteases MMP-1 and -9 and the Ets 1 transcription factor in HNPCC carcinomas and sporadic colorectal cancers. PMID: 12949792 Ref: [Polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 in colorectal cancer]. PMID: 14574887 Ref: Novel retinoic acid derivative ABPN has potent inhibitory activity on cell growth and apoptosis in cancer cells. PMID: 14601067 Ref: Low collagenase-1 (MMP-1) and MT1-MMP expression levels are favourable survival markers in advanced colorectal carcinoma. PMID: 14707454 |
Ref: Role of matrix metalloproteinases (MMPs) in colorectal cancer. PMID: 15000152 Ref: Simultaneous determination of matrix metalloproteinase (MMP)-7, MMP-1, -3, and -13 gene expression by multiplex PCR in colorectal carcinomas. PMID: 15103490 Ref: Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel. PMID: 15185339 Ref: Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers. PMID: 15623598 |
Ref: Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer. PMID: 15592677 Ref: Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. PMID: 15695237 Ref: Prognostic significance of MMP-1 and MMP-3 functional promoter polymorphisms in colorectal cancer. PMID: 15701845 Ref: The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15. PMID: 15767558 Ref: [Effect of NGX6 on gene expression profile of colon carcinoma cell line HT-29]. PMID: 16159426 |
Ref: Matrix metalloproteinase (MMP) -1, -2, -3 and -9 promoter polymorphisms in colorectal cancer. PMID: 16739355 Ref: Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. PMID: 16885380 Ref: No association between the polymorphisms in matrix metalloproteinase-1 and matrix metalloproteinase-3 promoter regions and colorectal cancer in Chinese. PMID: 16937230 Ref: Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-ras oncogene. PMID: 17089045 Ref: Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma. PMID: 17125518 |
Ref: Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation. PMID: 17109104 Ref: The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer. PMID: 17311017 Ref: Haplotype effects on matrix metalloproteinase-1 gene promoter activity in cancer cells. PMID: 17339606 Ref: Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer. PMID: 17455256 Ref: Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels. PMID: 17516864 Ref: Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. PMID: 17608852 Ref: Microfluidic reveals generation of platelet-strings on tumor-activated endothelium. PMID: 17721608 Ref: MMP-1 (collagenase-1) expression in primary colorectal cancer and its metastases. PMID: 17852862 |
Ref: Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma. PMID: 17543340 |
Ref: Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells. PMID: 19221016 Ref: Differences in the gene expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in primary colorectal tumors and their synchronous liver metastases. PMID: 19331134 Ref: Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects. PMID: 19507256 Ref: Role of deleted in colon carcinoma in osteoarthritis and in chondrocyte migration. PMID: 19745029 Ref: Differing expression of metalloprotease and of adhesion molecules in signet-ring cell and intestinal colorectal carcinoma. PMID: 20032387 Ref: Tumor self-seeding by circulating cancer cells. PMID: 20064377 |
Ref: Elevated intraperitoneal matrix metalloproteinases-8 and -9 in patients who develop anastomotic leakage after rectal cancer surgery: a pilot study. PMID: 19508511 Ref: A comparative study of protein expression in primary colorectal cancer and synchronous hepatic metastases: the significance of matrix metalloproteinase-1 expression as a predictor of liver metastasis. PMID: 20095886 Ref: Anti-proliferative and anti-cancer properties of Achyranthes aspera: specific inhibitory activity against pancreatic cancer cells. PMID: 20541002 Ref: Serum matrix-metalloproteinase-1 is a bona fide prognostic marker for colorectal cancer. PMID: 20617463 Ref: Association of matrix metalloproteinases 1, 7, and 9 gene polymorphisms with genetic susceptibility to colorectal carcinoma in a Han Chinese population. PMID: 20662554 |
Ref: Regulation of p21, MMP-1, and MDR-1 expression in human colon carcinoma HT29 cells by Tian Xian liquid, a chinese medicinal formula, in vitro and in vivo. PMID: 20702488 Ref: Cell-cell contacts induce STAT3 activity in colon carcinoma cells through an autocrine stimulation loop. PMID: 20830487 Ref: Preanalytical interferences compromise the clinical validity of matrix metalloproteinase 1 as marker of colorectal cancer. PMID: 21184189 Ref: STAT3 controls matrix metalloproteinase-1 expression in colon carcinoma cells by both direct and AP-1-mediated interaction with the MMP-1 promoter. PMID: 21410405 Ref: Absence of MMP2 expression correlates with poor clinical outcomes in rectal cancer, and is distinct from MMP1-related outcomes in colon cancer. PMID: 21531813 Ref: Meta-analysis of associations between polymorphisms in the promoter regions of matrix metalloproteinases and the risk of colorectal cancer. PMID: 21538057 Ref: Heterogeneity of metalloproteinase expression in colorectal cancer - relation of molecular findings to basic morphology. PMID: 21617211 Ref: The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor. PMID: 21672235 Ref: Prognostic and predictive potential molecular biomarkers in colon cancer. PMID: 21696062 Ref: High molecular weight coffee melanoidins are inhibitors for matrix metalloproteases. PMID: 21961901 Ref: Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cells. PMID: 22027145 Ref: [Expression of matrix metalloproteinase 1 in tissue of colon carcinoma and its clinical prognostic significance]. PMID: 22333608 |
Ref: MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1. PMID: 22198213 Ref: Identification of colorectal cancer metastasis markers by an angiogenesis-related cytokine-antibody array. PMID: 22363134 Ref: Effect of the expression of matrix metalloproteases and their tissue inhibitors on survival of patients with resectable colorectal cancer. PMID: 22488635 Ref: Cucurbitacin L 2-O-beta-Glucoside Demonstrates Apoptogenesis in Colon Adenocarcinoma Cells (HT-29): Involvement of Reactive Oxygen and Nitrogen Species Regulation. PMID: 22685485 Ref: Inhibitory effect of inositol hexaphosphate on metalloproteinases transcription in colon cancer cells stimulated with phorbol-12-myristate 13-acetate. PMID: 23285695 |
Ref: Intestinal mucosal MMP-1 - a prognostic factor in colon cancer. PMID: 23485198 Ref: Association between promoters polymorphisms of matrix metalloproteinases and risk of digestive cancers: a meta-analysis. PMID: 23644699 Ref: Angiogenesis-, metastasis- and signaling pathway-related factor dynamics in human colon cancer cells following interaction with monocytes. PMID: 23780976 Ref: The association of matrix metalloproteinase-1 genetic polymorphism (-1607 1G>2G) with colorectal cancer: a meta-analysis. PMID: 23873107 |
Ref: Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases. PMID: 24292449 Ref: The role of matrix metalloproteinases in colorectal cancer. PMID: 24518611 Ref: Association between matrix metalloproteinase 1 -1607 1G>2G polymorphism and cancer risk: a meta-analysis including 19706 subjects. PMID: 25356173 Ref: The influence of the CHIEF pathway on colorectal cancer-specific mortality. PMID: 25541970 |
Ref: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling. PMID: 24497447 Ref: Nuclear Factor Kappa B, Matrix Metalloproteinase-1, p53, and Ki-67 Expressions in the Primary Tumors and the Lymph Node Metastases of Colorectal Cancer Cases. PMID: 25945089 Ref: Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis. PMID: 26034135 Ref: Microarray analysis of anti-cancer effects of docosahexaenoic acid on human colon cancer model in nude mice. PMID: 26131080 |
Ref: Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway. PMID: 26530054 Ref: Dexamethasone Inhibits TGF-beta1-Induced Cell Migration by Regulating the ERK and AKT Pathways in Human Colon Cancer Cells Via CYR61. PMID: 26693911 Ref: CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling. PMID: 26719016 Ref: PITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant Secretion. PMID: 26977884 Ref: Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer. PMID: 27330311 Ref: Matrix metalloproteinases MMP1, MMP2, MMP9 and their tissue inhibitors TIMP1, TIMP2, TIMP3 in head and neck cancer: an immunohistochemical study. PMID: 27386931 Ref: Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells. PMID: 27566200 Ref: BACH1 silencing by siRNA inhibits migration of HT-29 colon cancer cells through reduction of metastasis-related genes. PMID: 27657827 |
Ref: Comprehensive and Holistic Analysis of HT-29 Colorectal Cancer Cells and Tumor-Bearing Nude Mouse Model: Interactions Among Fractions Derived From the Chinese Medicine Formula Tian Xian Liquid in Effects on Human Colorectal Carcinoma. PMID: 27261455 Ref: Anacyclus Pyrethrum Extract Exerts Anticancer Activities on the Human Colorectal Cancer Cell Line (HCT) by Targeting Apoptosis, Metastasis and Cell Cycle Arrest. PMID: 27796737 Ref: Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells. PMID: 28008134 Ref: Matrix metalloproteases expression in different histological types of colorectal polyps. PMID: 28376625 Ref: The integrated pathway of TGFbeta/Snail with TNFalpha/NFkappaB may facilitate the tumor-stroma interaction in the EMT process and colorectal cancer prognosis. PMID: 28687755 Ref: Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival. PMID: 28956832 Ref: The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo. PMID: 29048673 Ref: Scutellaria barbata D. Don inhibits migration and invasion of colorectal cancer cells via suppression of PI3K/AKT and TGF-beta/Smad signaling pathways. PMID: 29285087 Ref: Role of DDX3 in the pathogenesis of inflammatory bowel disease. PMID: 29383159 |
Ref: Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer. PMID: 29342159 Ref: Targeting M3 Muscarinic Receptors for Colon Cancer Therapy. PMID: 29357811 Ref: Role of matrix metalloproteinases in tumour invasion: immunohistochemistry of peritoneum from peritoneal carcinomatosis. PMID: 29623449 Ref: Identification of Critical Genes and Five Prognostic Biomarkers Associated with Colorectal Cancer. PMID: 29973580 Ref: Interaction of STAT3 and RelB modulates MMP-1 in colon cancer. PMID: 30040915 Ref: CRP and LOX-1: a Mechanism for Increasing the Tumorigenic Potential of Colorectal Cancer Carcinoma Cell Line. PMID: 30368730 |