Primary Site >> Colorectal Cancer

Gene >> MLKL

  • 2015
  • 2016
  • 2017
  • 2018
Ref: Cobalt chloride induces necroptosis in human colon cancer HT-29 cells.
PMID: 25824798
Ref: Key roles of necroptotic factors in promoting tumor growth.
PMID: 26959742
Ref: Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.
PMID: 28414098
Ref: Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo.
PMID: 28649853
Ref: Antitumor activity of HPA3P through RIPK3-dependent regulated necrotic cell death in colon cancer.
PMID: 29487701
Ref: Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.
PMID: 30143632