Primary Site >> Esophagus Cancer

Gene >> MLH1

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Ref: [One of the etiological factors of digestive tract cancers in Chinese: the missense mutation Val384Asp in the hMLH1 gene].
PMID: 10751526
Ref: [Update on gastroenterology].
PMID: 10903787
 Ref: Mismatch repair and microsatellite instability in esophageal cancer cells.
PMID: 11267981
Ref: [Esophageal, gastric and colorectal tumors].
PMID: 11894400
 Ref: p53 Gene mutation and genetic instability in superficial multifocal esophageal squamous cell carcinoma.
PMID: 11894109
Ref: Report of 16 kindreds and one kindred with hMLH1 germline mutation.
PMID: 11925604
Ref: [Genealogical research of hereditary nonpolyposis colorectal cancer].
PMID: 12139794
 Ref: Reduced MLH1 expression after chemotherapy is an indicator for poor prognosis in esophageal cancers.
PMID: 14555508
Ref: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
PMID: 14633667
 Ref: Clinical features and mismatch repair gene mutation screening in Chinese patients with hereditary nonpolyposis colorectal carcinoma.
PMID: 15309712
 Ref: Frequent microsatellite instability in primary esophageal carcinoma associated with extraesophageal primary carcinoma.
PMID: 15540218
 Ref: Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus.
PMID: 16899597
 Ref: Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus.
PMID: 18847451
 Ref: Microsatellite instability analysis and its correlation with hMLH1 repair gene hypermethylation status in esophageal pathologies including cancers.
PMID: 21045259
 Ref: Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer.
PMID: 21674174
 Ref: DNA repair biomarkers predict response to neoadjuvant chemoradiotherapy in esophageal cancer.
PMID: 22000749
Ref: High-throughput genotyping in metastatic esophageal squamous cell carcinoma identifies phosphoinositide-3-kinase and BRAF mutations.
PMID: 22870241
 Ref: Role of hMLH1 in sterigmatocystin-induced G(2) phase arrest in human esophageal epithelial Het-1A cells in vitro.
PMID: 23296099
 Ref: Promoter methylation status of MGMT, hMSH2, and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma.
PMID: 24366688
Ref: Single nucleotide polymorphisms of DNA mismatch repair genes MSH2 and MLH1 confer susceptibility to esophageal cancer.
PMID: 25232430
 Ref: Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer.
PMID: 25436004
 Ref: In vitro study of human mutL homolog 1 hypermethylation in inducing drug resistance of esophageal carcinoma.
PMID: 26782688
Ref: Expression of methylation-modulated tumor-related genes in endoscopically resected early esophageal squamous neoplasia.
PMID: 28693228
Ref: MLH1 expression predicts the response to preoperative therapy and is associated with PD-L1 expression in esophageal cancer.
PMID: 28693258
Ref: [High throughput-targeted sequencing panel for exploring radiosensitivity associated genes in esophageal squamous cell carcinoma].
PMID: 28835080
Ref: S100A14 rs11548103 G>A polymorphism is associated with a decreased risk of esophageal cancer in a Chinese population.
PMID: 29156846
 Ref: Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance.
PMID: 29440913