Primary Site >> Stomach Cancer

Gene >> MICA

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Ref: The increase of MICA gene A9 allele associated with gastric cancer and less schirrous change.
PMID: 15150599
 Ref: Soluble ULBP suppresses natural killer cell activity via down-regulating NKG2D expression.
PMID: 16630603
 Ref: Decreased NKG2D expression on CD8+ T cell is involved in immune evasion in patients with gastric cancer.
PMID: 17255258
 Ref: Induction of NKG2D ligands and increased sensitivity of tumor cells to NK cell-mediated cytotoxicity by hematoporphyrin-based photodynamic therapy.
PMID: 21314289
 Ref: Interleukin-1beta enhances the production of soluble MICA in human hepatocellular carcinoma.
PMID: 22302133
Ref: Midkine upregulates MICA/B expression in human gastric cancer cells and decreases natural killer cell cytotoxicity.
PMID: 22415659
 Ref: Potential therapeutic strategy for gastric cancer peritoneal metastasis by NKG2D ligands-specific T cells.
PMID: 26543378
Ref: MHC I-related chain a expression in gastric carcinoma and the efficacy of immunotherapy with cytokine-induced killer cells.
PMID: 26693072
 Ref: Tumor MICA status predicts the efficacy of immunotherapy with cytokine-induced killer cells for patients with gastric cancer.
PMID: 26607264
Ref: Clinical significance of tumor expression of major histocompatibility complex class I-related chains A and B (MICA/B) in gastric cancer patients.
PMID: 26708143
Ref: Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility.
PMID: 27002316
 Ref: Human fused NKG2D-IL-15 protein controls xenografted human gastric cancer through the recruitment and activation of NK cells.
PMID: 26364916