Primary Site >> Colorectal Cancer

Gene >> MICA

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Ref: Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2).
PMID: 11287116
Ref: Alternatively spliced forms of MICA and MICB lacking exon 3 in a human cell line and evidence of presence of similar RNA in human peripheral blood mononuclear cells.
PMID: 12466900
Ref: NKG2D engagement of colorectal cancer-specific T cells strengthens TCR-mediated antigen stimulation and elicits TCR independent anti-tumor activity.
PMID: 12884870
Ref: Analysis of MICA gene transcripts in human rectal cancers.
PMID: 12894536
Ref: Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients.
PMID: 16184547
Ref: Vgamma9Vdelta2 T cell-mediated recognition of human solid tumors. Potential for immunotherapy of hepatocellular and colorectal carcinomas.
PMID: 17764010
Ref: TNK cells (NKG2D+ CD8+ or CD4+ T lymphocytes) in the control of human tumors.
PMID: 19089424
Ref: Association of MICA-TM and MICB C1_2_A microsatellite polymorphisms with tumor progression in patients with colorectal cancer.
PMID: 19353249
Ref: Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy--a case report.
PMID: 19549307
Ref: [Association of MICA gene polymorphism and serum soluble MICA level with colorectal cancer].
PMID: 20533278
Ref: Induction of a less aggressive phenotype in human colon carcinoma HCT116 cells by chronic exposure to HDAC inhibitor SAHA.
PMID: 20878117
Ref: [Immunochemical assay of MIC A production by tumor cells in vitro and in vivo as a component of antitumor vaccine development].
PMID: 21137238
Ref: Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells.
PMID: 21257710
Ref: The effect of photodynamic therapy on tumor cell expression of major histocompatibility complex (MHC) class I and MHC class I-related molecules.
PMID: 22246985
Ref: Interleukin-1beta enhances the production of soluble MICA in human hepatocellular carcinoma.
PMID: 22302133
Ref: Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells.
PMID: 23883349
Ref: Enhanced sensitivity of colon tumour cells to natural killer cell cytotoxicity after mild thermal stress is regulated through HSF1-mediated expression of MICA.
PMID: 23902341
Ref: gammadelta T cells as a potential tool in colon cancer immunotherapy.
PMID: 25341120
Ref: The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells.
PMID: 24203492
Ref: Methylation of NKG2D ligands contributes to immune system evasion in acute myeloid leukemia.
PMID: 25393931
Ref: [Resveratrol inhibits cell proliferation and up-regulates MICA/B expression in human colon cancer stem cells].
PMID: 26146056
Ref: In Vitro Killing of Colorectal Carcinoma Cells by Autologous Activated NK Cells is Boosted by Anti-Epidermal Growth Factor Receptor-induced ADCC Regardless of RAS Mutation Status.
PMID: 29293164
Ref: NKG2D Immunoligand rG7S-MICA Enhances NK Cell-mediated Immunosurveillance in Colorectal Carcinoma.
PMID: 29528990