Primary Site >> Stomach Cancer
Gene >> MGMT
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Ref: O6-methylguanine-DNA methyltransferase activity in human tumors. PMID: 1394831 |
Ref: A polymorphism at codon 160 of human O6-methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay. PMID: 7586149 |
Ref: Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma. PMID: 11519041 Ref: Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma. PMID: 11753949 Ref: Expression and prognostic significance of O6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers. PMID: 11776495 Ref: Promoter methylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa. PMID: 11872960 |
Ref: Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. PMID: 11891177 |
Ref: Evaluation of O6-methylguanine DNA methyltransferase activity in patients with gastric cancer. PMID: 12659421 Ref: Tumour suppressor gene expression correlates with gastric cancer prognosis. PMID: 12692839 Ref: Profile of aberrant CpG island methylation along multistep gastric carcinogenesis. PMID: 12695555 Ref: Profile of aberrant CpG island methylation along the multistep pathway of gastric carcinogenesis. PMID: 12746473 Ref: Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas. PMID: 12763209 Ref: Future prospects of personalized chemotherapy in gastric cancer patients: results of a prospective randomized pilot study. PMID: 12775025 Ref: Loss of expression of DNA repair enzymes MGMT, hMLH1, and hMSH2 during tumor progression in gastric cancer. PMID: 12861399 Ref: Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation. PMID: 14507661 Ref: DNA methylation of multiple genes in gastric carcinoma: association with histological type and CpG island methylator phenotype. PMID: 14556664 Ref: Multigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral blood. PMID: 15068392 |
Ref: Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy. PMID: 15240535 Ref: BRAF/K-ras mutation, microsatellite instability, and promoter hypermethylation of hMLH1/MGMT in human gastric carcinomas. PMID: 15616773 |
Ref: Selected DNA repair polymorphisms and gastric cancer in Poland. PMID: 15802298 Ref: DNA hypermethylation of tumor-related genes in gastric carcinoma. PMID: 15831994 Ref: Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer. PMID: 15942635 |
Ref: Accumulation of DNA methylation is associated with tumor stage in gastric cancer. PMID: 16475210 Ref: CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus. PMID: 16707594 Ref: Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma. PMID: 16805821 Ref: An inverse correlation between Interleukin-6 and select gene promoter methylation in patients with gastric cancer. PMID: 17139167 |
Ref: [Hierarchical clustering analysis to detect associations between clinical and pathological features of gastric tumors and hypermethylation of suppressor genes]. PMID: 17369979 Ref: Aberrant methylation of multiple genes in gastric carcinomas. PMID: 17652530 Ref: Methylation of tumor-related genes in neoadjuvant-treated gastric cancer: relation to therapy response and clinicopathologic and molecular features. PMID: 17785563 Ref: Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients. PMID: 18008030 Ref: [Frequent promoter hypermethylation of several tumor suppressor genes in gastric carcinoma and foveolar epithelium]. PMID: 18069630 Ref: Genetic and epigenetic markers to identify high risk patients for multiple early gastric cancers after treatment with endoscopic mucosal resection. PMID: 18398497 |
Ref: Reprimo as a potential biomarker for early detection in gastric cancer. PMID: 18829507 Ref: Circulating DNA in the blood of gastric cancer patients. PMID: 18837952 Ref: DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis. PMID: 19399343 |
Ref: Influence of Helicobacter pylori infection on the expression of MLH1 and MGMT in patients with chronic gastritis and gastric cancer. PMID: 19089477 Ref: Biological significance of promoter hypermethylation of tumor-related genes in patients with gastric carcinoma. PMID: 19336228 Ref: Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions. PMID: 19695681 Ref: [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. PMID: 19742343 Ref: Methylation of the MGMT gene is frequently detected in advanced gastric carcinoma. PMID: 20044616 |
Ref: Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells. PMID: 19857042 Ref: Aberrant methylation of DNA mismatch repair genes in elderly patients with sporadic gastric carcinoma: A comparison with younger patients. PMID: 19894224 Ref: Aberrant gene methylation in the lymph nodes provides a possible marker for diagnosing micrometastasis in gastric cancer. PMID: 19957042 Ref: Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer. PMID: 20178103 Ref: Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer. PMID: 20704706 Ref: Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer. PMID: 20817763 |
Ref: Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). PMID: 21831520 |
Ref: Prognostic significance of aberrant gene methylation in gastric cancer. PMID: 22206050 Ref: Promoter methylation of tumor-related genes in gastric carcinogenesis. PMID: 22936446 |
Ref: Human metastable epiallele candidates link to common disorders. PMID: 23321599 Ref: Diet folate, DNA methylation and polymorphisms in methylenetetrahydrofolate reductase in association with the susceptibility to gastric cancer. PMID: 23534741 Ref: MGMT and MLH1 methylation in Helicobacter pylori-infected children and adults. PMID: 23716983 Ref: Aberrant DNA methylation of P16, MGMT, hMLH1 and hMSH2 genes in combination with the MTHFR C677T genetic polymorphism in gastric cancer. PMID: 23803092 Ref: Aberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in gastric cancer. PMID: 24550949 |
Ref: Two DNA repair gene polymorphisms on the risk of gastrointestinal cancers: a meta-analysis. PMID: 24203816 Ref: Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer. PMID: 24737431 Ref: p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer. PMID: 24816738 Ref: Aberrant DNA methylation of MGMT and hMLH1 genes in prediction of gastric cancer. PMID: 24938706 Ref: MGMT gene silencing by promoter hypermethylation in gastric cancer in a high incidence area. PMID: 25008999 Ref: [Promoter region methylation of DNA damage repair genes in human gastric cancer]. PMID: 25331470 Ref: Epigenetic alterations in a gastric leiomyoma. PMID: 25544907 |
Ref: Predictive value of CHFR and MLH1 methylation in human gastric cancer. PMID: 24748501 Ref: Tumor profiling of gastric and esophageal carcinoma reveal different treatment options. PMID: 25778705 Ref: Atomic Insight into the Altered O6-Methylguanine-DNA Methyltransferase Protein Architecture in Gastric Cancer. PMID: 26011121 Ref: Aberrant methylation patterns in cancer: a clinical view. PMID: 26110029 |
Ref: Gene methylation profile of gastric cancerous tissue according to tumor site in the stomach. PMID: 26810771 Ref: Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFkappaB pathway in gastric cancer development. PMID: 26848521 Ref: Braf, Kras and Helicobacter pylori epigenetic changes-associated chronic gastritis in Egyptian patients with and without gastric cancer. PMID: 27116958 Ref: O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2. PMID: 27291049 Ref: Relationships between MGMT promoter methylation and gastric cancer: a meta-analysis. PMID: 27785051 Ref: The Correlation of MGMT Promoter Methylation and Clinicopathological Features in Gastric Cancer: A Systematic Review and Meta-Analysis. PMID: 27824946 Ref: Diminished expression of MGMT & RASSF1A genes in gastric cancer in ethnic population of Kashmir. PMID: 28078123 |
Ref: The Association Between MGMT Promoter Methylation and Patients with Gastric Cancer: A Meta-Analysis. PMID: 28384044 Ref: Promoter hypermethylation of MGMT gene may contribute to the pathogenesis of gastric cancer: A PRISMA-compliant meta-analysis. PMID: 28445279 Ref: Association of O6-Methylguanine-DNA Methyltransferase Protein Expression With Postoperative Prognosis and Adjuvant Chemotherapeutic Benefits Among Patients With Stage II or III Gastric Cancer. PMID: 28903131 Ref: The intricate interplay between MSI and polymorphisms of DNA repair enzymes in gastric cancer H.pylori associated. PMID: 28927196 Ref: Promoter methylation of tumor-related genes as a potential biomarker using blood samples for gastric cancer detection. PMID: 29100425 Ref: Crosstalk between mismatch repair and base excision repair in human gastric cancer. PMID: 29156686 |