Primary Site >> Liver Cancer
Gene >> MGAT3
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Ref: Progression of hepatic neoplasms is severely retarded in mice lacking the bisecting N-acetylglucosamine on N-glycans: evidence for a glycoprotein factor that facilitates hepatic tumor progression. PMID: 9661906 |
Ref: New evidence for an extra-hepatic role of N-acetylglucosaminyltransferase III in the progression of diethylnitrosamine-induced liver tumors in mice. PMID: 10866326 |
Ref: Truncated, inactive N-acetylglucosaminyltransferase III (GlcNAc-TIII) induces neurological and other traits absent in mice that lack GlcNAc-TIII. PMID: 11986323 |
Ref: The bisecting GlcNAc on N-glycans inhibits growth factor signaling and retards mammary tumor progression. PMID: 20395209 |
Ref: Cell surface glycan alterations in epithelial mesenchymal transition process of Huh7 hepatocellular carcinoma cell. PMID: 23977005 |
Ref: Expression of N-Acetylglucosaminyltransferase III Suppresses alpha2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to alpha2,6-Sialylation Levels. PMID: 26801611 Ref: DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins. PMID: 27073020 |
Ref: Reduced N-acetylglucosaminyltransferase III expression via Smad3 and Erk signaling in TGF-beta1-induced HCC EMT model. PMID: 28245423 |