Primary Site >> Colorectal Cancer

Gene >> MCAM

  • 2006
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  • 2016
Ref: Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.
PMID: 16549839
Ref: Endothelial differentiation potential of human monocyte-derived multipotential cells.
PMID: 16888284
Ref: High-throughput methylation profiling by MCA coupled to CpG island microarray.
PMID: 17785535
Ref: Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells.
PMID: 19795419
Ref: Molecular changes consistent with increased proliferation and invasion are common in rectal cancer.
PMID: 21975339
Ref: Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
PMID: 23563852
Ref: CD146 protein as a marker to predict postoperative liver metastasis in colorectal cancer.
PMID: 23745687
Ref: Targeting endothelial CD146 attenuates colitis and prevents colitis-associated carcinogenesis.
PMID: 24767106
Ref: Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells.
PMID: 24892449
Ref: Increased pre-surgical numbers of endothelial progenitor cells and circulating endothelial cells in colorectal cancer fail to predict outcome.
PMID: 25598043
Ref: The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma.
PMID: 25728681
Ref: MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome.
PMID: 26921326
Ref: Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity.
PMID: 27149858
Ref: Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/beta-catenin signaling.
PMID: 27302922