Primary Site >> Colorectal Cancer

Gene >> MBTPS1

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Ref: Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.
PMID: 11402025
Ref: The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.
PMID: 12552133
Ref: Sphingosine kinase 1 is up-regulated in colon carcinogenesis.
PMID: 16319132
Ref: Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate.
PMID: 17652460
Ref: VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo.
PMID: 19219548
Ref: Identification of 33 candidate oncogenes by screening for base-specific mutations.
PMID: 25117815
Ref: Sphingolipid metabolism in colorectal adenomas varies depending on histological architecture of polyps and grade of nuclear dysplasia.
PMID: 25595595
Ref: Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
PMID: 25907800
Ref: Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.
PMID: 26809095
Ref: Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer.
PMID: 27050145