Primary Site >> Stomach Cancer
Gene >> MAPK8
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Ref: Enhancement of chemotherapeutic agents induced-apoptosis associated with activation of c-Jun N-terminal kinase 1 and caspase 3 (CPP32) in bax-transfected gastric cancer cells. PMID: 10769693 |
Ref: Helicobacter pylori induced transactivation of SRE and AP-1 through the ERK signalling pathway in gastric cancer cells. PMID: 11413105 Ref: Helicobacter pylori induces apoptosis in human epithelial gastric cells by stress activated protein kinase pathway. PMID: 11422465 Ref: IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1. PMID: 11751424 Ref: Effect of vitamin E succinate on expression of TGF-beta1, c-Jun and JNK1 in human gastric cancer SGC-7901 cells. PMID: 11819738 |
Ref: Expression of WRCH1 in human cancer and down-regulation of WRCH1 by beta-estradiol in MCF-7 cells. PMID: 11894124 Ref: Molecular cloning and characterization of WRCH2 on human chromosome 15q15. PMID: 11956592 Ref: Molecular cloning and characterization of Strabismus 2 (STB2). PMID: 11956595 Ref: Frequent up-regulation of WNT5A mRNA in primary gastric cancer. PMID: 11956659 Ref: Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer. PMID: 12239632 Ref: Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells. PMID: 12439916 Ref: MAPK signaling is involved in camptothecin-induced cell death. PMID: 12521296 |
Ref: Bcl-w is expressed in a majority of infiltrative gastric adenocarcinomas and suppresses the cancer cell death by blocking stress-activated protein kinase/c-Jun NH2-terminal kinase activation. PMID: 12615727 Ref: Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells. PMID: 12720296 Ref: P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells. PMID: 12883725 |
Ref: Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase. PMID: 14699495 Ref: c-Jun N-terminal kinase is required for vitamin E succinate-induced apoptosis in human gastric cancer cells. PMID: 15069708 Ref: EGCG blocks tumor promoter-induced MMP-9 expression via suppression of MAPK and AP-1 activation in human gastric AGS cells. PMID: 15161022 |
Ref: Characterization of the molecular forms of glutathione S-transferase P1 in human gastric cancer cells (Kato III) and in normal human erythrocytes. PMID: 15471539 Ref: Urokinase plasminogen activator receptor is upregulated by Helicobacter pylori in human gastric cancer AGS cells via ERK, JNK, and AP-1. PMID: 15963460 Ref: Immuno-regulatory effects of CKBM on the activities of mitogen-activated protein kinases and the release of cytokines in THP-1 monocytic cells. PMID: 16141532 Ref: Analysis on the mechanism of Helicobacter pylori-induced apoptosis in gastric cancer cell line BGC-823. PMID: 16142414 Ref: WNT/PCP signaling pathway and human cancer (review). PMID: 16273260 |
Ref: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers. PMID: 16337741 Ref: Analysis of common gene expression patterns in four human tumor cell lines exposed to camptothecin using cDNA microarray: identification of topoisomerase-mediated DNA damage response pathways. PMID: 16368568 Ref: Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells. PMID: 16371352 Ref: Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation. PMID: 16596182 Ref: IL-18 enhances thrombospondin-1 production in human gastric cancer via JNK pathway. PMID: 16650813 |
Ref: alpha-Tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner. PMID: 16839662 Ref: Chemopreventive properties of Hibiscus sabdariffa L. on human gastric carcinoma cells through apoptosis induction and JNK/p38 MAPK signaling activation. PMID: 17145051 Ref: Rebamipide inhibits gastric cancer cell growth. PMID: 17171453 Ref: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. PMID: 17273778 Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new "hot" cancer treatment. PMID: 17292493 Ref: Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation. PMID: 17304508 Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. PMID: 17568183 Ref: IL-17A versus IL-17F induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in AGS gastric adenocarcinoma cells. PMID: 17644350 Ref: Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells. PMID: 17823871 Ref: Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kappaB pathway. PMID: 17909069 Ref: Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells. PMID: 17970088 |
Ref: Lysophosphatidic acid promotes cell invasion by up-regulating the urokinase-type plasminogen activator receptor in human gastric cancer cells. PMID: 18247343 Ref: CPT21, a novel compound with anti-proliferative effect against gastric cancer cell SGC7901. PMID: 18283417 Ref: [Study on the mechanism of DDP-resistance mediated by phosphate JNK in gastric cancer]. PMID: 18344085 Ref: c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice. PMID: 18593901 Ref: Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells. PMID: 18619958 Ref: Glibenclamide exerts an antitumor activity through reactive oxygen species-c-jun NH2-terminal kinase pathway in human gastric cancer cell line MGC-803. PMID: 18840412 |
Ref: Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain. PMID: 19014919 Ref: Proliferative effects of gamma-aminobutyric acid on the gastric cancer cell line are associated with extracellular signal-regulated kinase 1/2 activation. PMID: 19032445 Ref: Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades. PMID: 19424602 Ref: SP600125, an inhibitor of Jnk pathway, reduces viability of relatively resistant cancer cells to doxorubicin. PMID: 19607816 Ref: TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways. PMID: 19657566 Ref: Activator protein-1 mediates docosahexaenoic acid-induced apoptosis of human gastric cancer cells. PMID: 19723051 |
Ref: Early antiallergic inflammatory effects of Rhus verniciflua Stokes on human mast cells. PMID: 19653191 Ref: Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation. PMID: 20150185 Ref: Intracellular chloride regulates cell proliferation through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells. PMID: 20205250 Ref: Endoplasmic reticulum stress contributes to vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. PMID: 20435408 Ref: Hypoxia promotes metastasis in human gastric cancer by up-regulating the 67-kDa laminin receptor. PMID: 20491781 Ref: HIF-1alpha and HIF-2alpha correlate with migration and invasion in gastric cancer. PMID: 20559021 Ref: Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. PMID: 20804754 Ref: Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells. PMID: 20846373 |
Ref: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways. PMID: 20498032 Ref: Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells. PMID: 20799280 Ref: MSP-induced RON activation upregulates uPAR expression and cell invasiveness via MAPK, AP-1 and NF-kappaB signals in gastric cancer cells. PMID: 21081472 Ref: Upregulation of RhoB via c-Jun N-terminal kinase signaling induces apoptosis of the human gastric carcinoma NUGC-3 cells treated with NSC12618. PMID: 21084431 Ref: Differences of immunophenotypic markers and signaling molecules between adenocarcinomas of gastric cardia and distal stomach. PMID: 21146193 Ref: Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. PMID: 21287681 Ref: Cellular and molecular mechanisms of the Ganoderma applanatum extracts induces apoptosis on SGC-7901 gastric cancer cells. PMID: 21465494 Ref: Proteomics characterization of gastrokine 1-induced growth inhibition of gastric cancer cells. PMID: 21751384 Ref: Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer. PMID: 21785822 Ref: Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways. PMID: 21786165 Ref: Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-kappaB inhibitors in ovarian cancer therapy. PMID: 21931671 Ref: Intracellular chloride regulates the G(1)/S cell cycle progression in gastric cancer cells. PMID: 22007274 |
Ref: Knockdown of metallopanstimulin-1 inhibits NF-kappaB signaling at different levels: the role of apoptosis induction of gastric cancer cells. PMID: 21796632 Ref: Galangin induces apoptosis in gastric cancer cells via regulation of ubiquitin carboxy-terminal hydrolase isozyme L1 and glutathione S-transferase P. PMID: 22142694 Ref: P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis. PMID: 22293972 Ref: E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells. PMID: 22322152 Ref: 125I seed irradiation induces up-regulation of the genes associated with apoptosis and cell cycle arrest and inhibits growth of gastric cancer xenografts. PMID: 22827957 Ref: Molecular marker identification for relapse prediction in 5-FU-based adjuvant chemotherapy in gastric and colorectal cancers. PMID: 22905237 Ref: [Mechanisms of (2-methyl-n-butyl) shikonin induced apoptosis of gastric cancer SGC-7901 cells]. PMID: 22919733 Ref: Type II cGMP-dependent protein kinase inhibits ERK/JNK-mediated activation of transcription factors in gastric cancer cells. PMID: 22940826 Ref: Protein inhibitor of activated STAT-1 is downregulated in gastric cancer tissue and involved in cell metastasis. PMID: 22972521 Ref: Transgenic expression of the Helicobacter pylori virulence factor CagA promotes apoptosis or tumorigenesis through JNK activation in Drosophila. PMID: 23093933 Ref: c-Jun N-terminal kinase is required for thermotherapy-induced apoptosis in human gastric cancer cells. PMID: 23326144 |
Ref: SFRP5 inhibits gastric epithelial cell migration induced by macrophage-derived Wnt5a. PMID: 23054609 Ref: CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway. PMID: 23070808 Ref: CD81 is a candidate tumor suppressor gene in human gastric cancer. PMID: 23264205 Ref: Recombinant Erdr1 suppresses the migration and invasion ability of human gastric cancer cells, SNU-216, through the JNK pathway. PMID: 23370368 Ref: Transcriptional and post-translational regulation of Bim is essential for TGF-beta and TNF-alpha-induced apoptosis of gastric cancer cell. PMID: 23500081 Ref: Apoptosis of human gastric cancer cells line SGC 7901 induced by garlic-derived compound S-allylmercaptocysteine (SAMC). PMID: 23609357 Ref: N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1alpha by human gastric cancer cells. PMID: 23846687 Ref: Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells. PMID: 23850994 Ref: Genetic variants in epidermal growth factor receptor pathway genes and risk of esophageal squamous cell carcinoma and gastric cancer in a Chinese population. PMID: 23874846 Ref: Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress. PMID: 23881281 Ref: Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine. PMID: 24063987 Ref: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway. PMID: 24241351 Ref: Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells. PMID: 24273605 Ref: Buxus Microphylla var. Koreana Nakai Extract for the Treatment of Gastric Cancer. PMID: 25780674 |
Ref: Genetic variants in fas signaling pathway genes and risk of gastric cancer. PMID: 23921907 Ref: Ginsenoside F(2) induces apoptosis in humor gastric carcinoma cells through reactive oxygen species-mitochondria pathway and modulation of ASK-1/JNK signaling cascade in vitro and in vivo. PMID: 24252332 Ref: Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells. PMID: 24337453 Ref: Underexpressed CNDP2 participates in gastric cancer growth inhibition through activating the MAPK signaling pathway. PMID: 24395568 Ref: Capilliposide C derived from Lysimachia capillipes Hemsl inhibits growth of human prostate cancer PC3 cells by targeting caspase and MAPK pathways. PMID: 24554216 Ref: Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. PMID: 24647664 Ref: Synergistic Effect of Zuo Jin Wan on DDP-Induced Apoptosis in Human Gastric Cancer SGC-7901/DDP Cells. PMID: 24723962 Ref: Orostachys japonicus induces apoptosis and cell cycle arrest through the mitochondria-dependent apoptotic pathway in AGS human gastric cancer cells. PMID: 24789703 Ref: Oleanolic acid induces apoptosis of MKN28 cells via AKT and JNK signaling pathways. PMID: 24824325 Ref: SKI-II reverses the chemoresistance of SGC7901/DDP gastric cancer cells. PMID: 24959278 Ref: Association of CXCR1 and 2 expressions with gastric cancer metastasis in ex vivo and tumor cell invasion in vitro. PMID: 25022956 Ref: Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-kappaB, and AP-1 signaling pathways. PMID: 25069788 Ref: Analysis of T4SS-induced signaling by H. pylori using quantitative phosphoproteomics. PMID: 25101063 Ref: A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy. PMID: 25146681 Ref: Curcumin induced human gastric cancer BGC-823 cells apoptosis by ROS-mediated ASK1-MKK4-JNK stress signaling pathway. PMID: 25198898 Ref: 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression. PMID: 25342459 Ref: Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression. PMID: 25503137 Ref: Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer. PMID: 25594045 |
Ref: Schizandra chinensis extracts induce apoptosis in human gastric cancer cells via JNK/p38 MAPK activation and the ROS-mediated/mitochondria-dependent pathway. PMID: 25243868 Ref: NAIF1 inhibits gastric cancer cells migration and invasion via the MAPK pathways. PMID: 25432142 Ref: Bortezomib inhibits gastric carcinoma HGC-27 cells through the phospho-Jun N-terminal kinase (p-JNK) pathway in vitro. PMID: 25602436 Ref: Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2. PMID: 25652880 Ref: ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer. PMID: 25714022 Ref: Inhibitory effects of Saururus chinensis and its components on stomach cancer cells. PMID: 25765830 Ref: IL-33-induced JNK pathway activation confers gastric cancer chemotherapy resistance. PMID: 25846650 Ref: Chrysin inhibits tumor promoter-induced MMP-9 expression by blocking AP-1 via suppression of ERK and JNK pathways in gastric cancer cells. PMID: 25875631 Ref: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. PMID: 25981581 Ref: Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling. PMID: 25998184 Ref: Anti-tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC-803 proliferation via phospho-extracellular signal-regulated kinase-, Src-, c-Jun N-terminal kinase- and phosphoinositide 3-kinase-associated pathways. PMID: 26063313 Ref: Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke-induced Gastric Epithelial-Mesenchymal Transition in Mice. PMID: 26074474 Ref: Targeting Notch signaling by gamma-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer. PMID: 26134677 Ref: Lactotransferrin expression is downregulated and affects the mitogen-activated protein kinase pathway in gastric cancer. PMID: 26137081 Ref: Flavonoids isolated from Citrus platymamma induce mitochondrial-dependent apoptosis in AGS cells by modulation of the PI3K/AKT and MAPK pathways. PMID: 26165353 Ref: E-cadherin-defective gastric cancer cells depend on Laminin to survive and invade. PMID: 26246502 Ref: WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-gamma pathways. PMID: 26291058 Ref: The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-kappaB. PMID: 26371858 Ref: Fermented So-Cheong-Ryong-Tang (FCY) induces apoptosis via the activation of caspases and the regulation of MAPK signaling pathways in cancer cells. PMID: 26403976 Ref: Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. PMID: 26645893 |
Ref: Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation. PMID: 26086416 Ref: Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. PMID: 26205347 Ref: Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway. PMID: 26279301 Ref: Epstein-Barr Virus (EBV) Tegument Protein BGLF2 Promotes EBV Reactivation through Activation of the p38 Mitogen-Activated Protein Kinase. PMID: 26559845 Ref: Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis. PMID: 26577606 Ref: Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. PMID: 26612919 Ref: Sustained ERK activation-mediated proliferation inhibition of farrerol on human gastric carcinoma cell line by G0/G1-phase cell-cycle arrest. PMID: 26656929 Ref: Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib. PMID: 26683357 Ref: Downregulation of nonmuscle myosin IIA expression inhibits migration and invasion of gastric cancer cells via the cJun Nterminal kinase signaling pathway. PMID: 26719067 Ref: Iron chelator-induced apoptosis via the ER stress pathway in gastric cancer cells. PMID: 26803514 Ref: Suppression of IL-8-Src signalling axis by 17beta-estradiol inhibits human mesenchymal stem cells-mediated gastric cancer invasion. PMID: 26945908 Ref: Paclitaxel enhances tumoricidal potential of TRAIL via inhibition of MAPK in resistant gastric cancer cells. PMID: 26986870 Ref: Overexpression of Endoplasmic Reticulum Oxidoreductin 1-alpha (ERO1L) Is Associated with Poor Prognosis of Gastric Cancer. PMID: 26987398 Ref: Shikonin Induces Apoptotic Cell Death via Regulation of p53 and Nrf2 in AGS Human Stomach Carcinoma Cells. PMID: 27257011 Ref: c-Jun N-terminal kinase activation has a prognostic implication and is negatively associated with FOXO1 activation in gastric cancer. PMID: 27268017 Ref: Recombinant Newcastle disease virus (rL-RVG) triggers autophagy and apoptosis in gastric carcinoma cells by inducing ER stress. PMID: 27293989 Ref: Carbon monoxide releasing molecule-2 ameliorates IL-1beta-induced IL-8 in human gastric cancer cells. PMID: 27393034 Ref: Dihydrotanshinone induces apoptosis of SGC7901 and MGC803 cells via activation of JNK and p38 signalling pathways. PMID: 27431278 Ref: Inflammatory and Apoptotic Regulatory Activity of Tanshinone IIA in Helicobacter pylori-Infected Cells. PMID: 27627918 Ref: A novel polysaccharide derived from algae extract induces apoptosis and cell cycle arrest in human gastric carcinoma MKN45 cells via ROS/JNK signaling pathway. PMID: 27633119 Ref: Natriuretic peptide receptor A inhibition suppresses gastric cancer development through reactive oxygen species-mediated G2/M cell cycle arrest and cell death. PMID: 27634171 Ref: Long non-coding RNA CASC2 suppresses the proliferation of gastric cancer cells by regulating the MAPK signaling pathway. PMID: 27648142 Ref: Evaluation of a furochromone from the halophyte Corydalis heterocarpa for cytotoxic activity against human gastric cancer (AGS) cells. PMID: 27808331 Ref: Dapper homolog 1 alpha suppresses metastasis ability of gastric cancer through inhibiting planar cell polarity pathway. PMID: 27833078 Ref: HER2-induced metastasis is mediated by AKT/JNK/EMT signaling pathway in gastric cancer. PMID: 27895401 Ref: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines. PMID: 28459519 |
Ref: Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells. PMID: 27377703 Ref: Dihydroartemisinin induces apoptosis in human gastric cancer cell line BGC-823 through activation of JNK1/2 and p38 MAPK signaling pathways. PMID: 27401020 Ref: 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation. PMID: 28076833 Ref: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma. PMID: 28188923 Ref: Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway. PMID: 28223821 Ref: CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways. PMID: 28281844 Ref: Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment. PMID: 28344324 Ref: Melatonin treatment induces apoptosis through regulating the nuclear factor-kappaB and mitogen-activated protein kinase signaling pathways in human gastric cancer SGC7901 cells. PMID: 28454460 Ref: Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice. PMID: 28501767 Ref: p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2. PMID: 28534988 Ref: Combining TRAIL and liquiritin exerts synergistic effects against human gastric cancer cells and xenograft in nude mice through potentiating apoptosis and ROS generation. PMID: 28715876 Ref: [Quinalizarin induces apoptosis in gastric cancer AGS cells via MAPK and Akt signaling pathway]. PMID: 28801290 Ref: Roles of p38 and JNK protein kinase pathways activated by compound cantharidin capsules containing serum on proliferation inhibition and apoptosis of human gastric cancer cell line. PMID: 28810654 Ref: Antitumor effects of bakuchiol on human gastric carcinoma cell lines are mediated through PI3K/AKT and MAPK signaling pathways. PMID: 28990045 Ref: Decreased expression of the long non-coding RNA SLC7A11-AS1 predicts poor prognosis and promotes tumor growth in gastric cancer. PMID: 29348845 Ref: HOXC10 up-regulation promotes gastric cancer cell proliferation and metastasis through MAPK pathway. PMID: 29353980 Ref: Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells. PMID: 29383168 |
Ref: NR4A1-induced increase in the sensitivity of a human gastric cancer line to TNFalpha-mediated apoptosis is associated with the inhibition of JNK/Parkin-dependent mitophagy. PMID: 29207128 Ref: Long Noncoding RNA CAT104 Promotes Cell Viability, Migration, and Invasion in Gastric Carcinoma Cells Through Activation of MicroRNA-381-Inhibiting Zinc Finger E-box-Binding Homeobox 1 (ZEB1) Expression. PMID: 29295724 Ref: TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway. PMID: 29343514 Ref: 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human gastric cancer cells through downregulating JNK-mediated cytoprotective autophagy. PMID: 29383484 Ref: Over-expression of ARHGAP18 suppressed cell proliferation, migration, invasion, and tumor growth in gastric cancer by restraining over-activation of MAPK signaling pathways. PMID: 29386906 Ref: Gastroprotective effects of Hwanglyeonhaedok-tang against Helicobacter pylori-induced gastric cell injury. PMID: 29410309 Ref: Wogonin exacerbates the cytotoxic effect of oxaliplatin by inducing nitrosative stress and autophagy in human gastric cancer cells. PMID: 29433678 Ref: A novel polysaccharide derived from algae extract inhibits cancer progression via JNK, not via the p38 MAPK signaling pathway. PMID: 29512724 Ref: Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases. PMID: 29666306 Ref: MAPK/c-Jun signaling pathway contributes to the upregulation of the anti-apoptotic proteins Bcl-2 and Bcl-xL induced by Epstein-Barr virus-encoded BARF1 in gastric carcinoma cells. PMID: 29725459 Ref: Human Epidermal Growth Factor Receptor-2 Promotes Invasion and Metastasis in Gastric Cancer by Activating Mitogen-activated Protein Kinase Signaling. PMID: 29734245 Ref: Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity. PMID: 29767555 Ref: SIRT2 Promotes the Migration and Invasion of Gastric Cancer through RAS/ERK/JNK/MMP-9 Pathway by Increasing PEPCK1-Related Metabolism. PMID: 29925042 Ref: Knockdown of long non-coding RNA PEG10 inhibits growth, migration and invasion of gastric carcinoma cells via up-regulating miR-3200. PMID: 29940767 Ref: Long noncoding RNA SNHG6 regulates p21 expression via activation of the JNK pathway and regulation of EZH2 in gastric cancer cells. PMID: 30031062 Ref: Netrin1 induces the proliferation of gastric cancer cells via the ERK/MAPK signaling pathway and FAK activation. PMID: 30106432 Ref: Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells. PMID: 30158521 Ref: Geniposide suppresses growth, migration and invasion of MKN45 cells by down-regulation of lncRNA HULC. PMID: 30176223 Ref: The compound 2-(naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via reactive oxygen species-regulated mitogen-activated protein kinase, protein kinase B, and signal transducer and activator of transcription 3 signaling in human gast PMID: 30222185 Ref: Anticancer Activity of Phloretin Against Human Gastric Cancer Cell Lines Involves Apoptosis, Cell Cycle Arrest, and Inhibition of Cell Invasion and JNK Signalling Pathway. PMID: 30224626 Ref: Mixed lineage kinase-4 promotes gastric carcinoma tumorigenesis through suppression of the c-Jun N-terminal kinase signaling pathway. PMID: 30233678 Ref: The Elevated ASK1 Expression Inhibits Proliferation and Invasion in Gastric Cancer HGC-27 Cells. PMID: 30324658 Ref: Proviral insertion in murine lymphomas 2 promotes stomach cancer progression by regulating apoptosis via reactive oxygen species-triggered endoplasmic reticulum stress. PMID: 30340823 Ref: [Aloin induces apoptosis via regulating the activation of MAPKs signaling pathway in human gastric cancer cells in vitro]. PMID: 30377097 |