Primary Site >> Biliary tract Cancer

Gene >> MAPK8

  • 2002
  • 2004
  • 2006
  • 2011
  • 2013
  • 2014
  • 2016
  • 2017
  • 2018
Ref: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line.
PMID: 11910351
 Ref: Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.
PMID: 14701718
Ref: Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis.
PMID: 14999691
 Ref: The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
PMID: 16525641
 Ref: Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor.
PMID: 21464819
 Ref: Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma.
PMID: 23505219
Ref: JNK inhibitor SP600125 enhances TGF-beta-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner.
PMID: 24100678
 Ref: GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
PMID: 24141775
Ref: Mycoepoxydiene induces apoptosis and inhibits TPA-induced invasion in human cholangiocarcinoma cells via blocking NF-kappaB pathway.
PMID: 24486723
Ref: Fibroblast Growth Factor 19 Activates the Unfolded Protein Response and Mitogen-Activated Protein Kinase Phosphorylation in H-69 Cholangiocyte Cells.
PMID: 29093991
 Ref: TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1/2/AP-1/VEGF-D pathway.
PMID: 26992854
 Ref: L1 Cell Adhesion Molecule Promotes Migration and Invasion via JNK Activation in Extrahepatic Cholangiocarcinoma Cells with Activating KRAS Mutation.
PMID: 28535665
Ref: Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.
PMID: 28609656
Ref: Piperlongumine induces G2/M phase arrest and apoptosis in cholangiocarcinoma cells through the ROS-JNK-ERK signaling pathway.
PMID: 28913568
Ref: Shikonin induces apoptosis and G0/G1 phase arrest of gallbladder cancer cells via the JNK signaling pathway.
PMID: 29039581
Ref: Autocrine parathyroid hormone-like hormone promotes intrahepatic cholangiocarcinoma cell proliferation via increased ERK/JNK-ATF2-cyclinD1 signaling.
PMID: 29178939
 Ref: IDH1 mutation correlates with a beneficial prognosis and suppresses tumor growth in IHCC.
PMID: 30278918
Ref: BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathways.
PMID: 30305612