Primary Site >> Stomach Cancer
Gene >> MAPK14
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Ref: Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways. PMID: 11686835 |
Ref: Chemotherapy induces lytic EBV replication and confers ganciclovir susceptibility to EBV-positive epithelial cell tumors. PMID: 11912175 Ref: SB203580, a P38 MAPK Inhibitor, Blocks in vitro Invasion by Human Gastric SNU-638 Cells. PMID: 26680899 |
Ref: P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells. PMID: 12883725 Ref: Involvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest. PMID: 12970909 Ref: TGFbeta1 activates c-Jun and Erk1 via alphaVbeta6 integrin. PMID: 14572313 |
Ref: Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. PMID: 14647439 Ref: [Diallyl disulfide-induced G2/M arrest of human gastric cancer MGC803 cells involves activation of p38 MAP kinase pathways]. PMID: 14960237 Ref: Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells. PMID: 15173094 Ref: Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. PMID: 15208668 Ref: Diallyl disulfide-induced G2/M arrest of human gastric cancer MGC803 cells involves activation of p38 MAP kinase pathways. PMID: 15309729 Ref: Reactivation of latent Epstein-Barr virus by methotrexate: a potential contributor to methotrexate-associated lymphomas. PMID: 15547182 |
Ref: NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages. PMID: 15561713 Ref: Genetics and prevention of oesophageal adenocarcinoma. PMID: 15648181 Ref: Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway. PMID: 15791651 Ref: Immuno-regulatory effects of CKBM on the activities of mitogen-activated protein kinases and the release of cytokines in THP-1 monocytic cells. PMID: 16141532 |
Ref: Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells. PMID: 16371352 Ref: Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation. PMID: 16596182 Ref: Inhibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer cells. PMID: 16641552 |
Ref: Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir. PMID: 16647201 Ref: Chemopreventive properties of Hibiscus sabdariffa L. on human gastric carcinoma cells through apoptosis induction and JNK/p38 MAPK signaling activation. PMID: 17145051 Ref: Ganciclovir augments the lytic induction and apoptosis induced by chemotherapeutic agents in an Epstein-Barr virus-infected gastric carcinoma cell line. PMID: 17159505 Ref: Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation. PMID: 17304508 Ref: IL-17A versus IL-17F induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in AGS gastric adenocarcinoma cells. PMID: 17644350 Ref: Thimerosal-induced apoptosis in human SCM1 gastric cancer cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation. PMID: 17698513 Ref: Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer. PMID: 17803652 Ref: Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2. PMID: 18025257 |
Ref: Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. PMID: 18378261 Ref: Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. PMID: 18395088 Ref: Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells. PMID: 18619958 Ref: Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. PMID: 18805435 Ref: EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-kappaB signaling in human gastric carcinoma cells. PMID: 19020743 Ref: Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells. PMID: 19091131 |
Ref: High concentrations of ascorbic acid induces apoptosis of human gastric cancer cell by p38-MAP kinase-dependent up-regulation of transferrin receptor. PMID: 19108947 Ref: Reactive oxygen species regulate urokinase plasminogen activator expression and cell invasion via mitogen-activated protein kinase pathways after treatment with hepatocyte growth factor in stomach cancer cells. PMID: 19497102 Ref: Kiss-1 suppresses MMP-9 expression by activating p38 MAP kinase in human stomach cancer. PMID: 20066900 |
Ref: Early antiallergic inflammatory effects of Rhus verniciflua Stokes on human mast cells. PMID: 19653191 Ref: R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75(NTR) induction. PMID: 19916560 Ref: Intracellular chloride regulates cell proliferation through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells. PMID: 20205250 Ref: Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of nuclear factor-kappaB. PMID: 20228839 |
Ref: Receptor activity modifying protein-3 mediates the protumorigenic activity of lysyl oxidase-like protein-2. PMID: 20802105 Ref: MSP-induced RON activation upregulates uPAR expression and cell invasiveness via MAPK, AP-1 and NF-kappaB signals in gastric cancer cells. PMID: 21081472 Ref: Differences of immunophenotypic markers and signaling molecules between adenocarcinomas of gastric cardia and distal stomach. PMID: 21146193 Ref: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro. PMID: 21261791 Ref: Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK. PMID: 21320468 Ref: CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. PMID: 21397861 Ref: FW523-3, a novel lipopeptide compound, induces apoptosis in cancer cells. PMID: 21584500 Ref: Intracellular chloride regulates the G(1)/S cell cycle progression in gastric cancer cells. PMID: 22007274 |
Ref: Antiproliferative effect of SOCS-1 through the suppression of STAT3 and p38 MAPK activation in gastric cancer cells. PMID: 22095154 Ref: Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasis. PMID: 22119383 |
Ref: Platycodin D induces anoikis and caspase-mediated apoptosis via p38 MAPK in AGS human gastric cancer cells. PMID: 22961809 Ref: CD81 is a candidate tumor suppressor gene in human gastric cancer. PMID: 23264205 Ref: Suppressive effects of an ethanol extract of Gleditsia sinensis thorns on human SNU-5 gastric cancer cells. PMID: 23381601 Ref: Migration of gastric cancer cells in response to lysophosphatidic acid is mediated by LPA receptor 2. PMID: 23426604 Ref: S100A8 and S100A9 promotes invasion and migration through p38 mitogen-activated protein kinase-dependent NF-kappaB activation in gastric cancer cells. PMID: 23456298 Ref: beta-Ionone arrests cell cycle of gastric carcinoma cancer cells by a MAPK pathway. PMID: 23536271 Ref: ERK1/2 signalling pathway is involved in CD147-mediated gastric cancer cell line SGC7901 proliferation and invasion. PMID: 23828593 Ref: Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells. PMID: 23850994 Ref: WD40 repeat-containing 62 overexpression as a novel indicator of poor prognosis for human gastric cancer. PMID: 23920402 Ref: Differential roles of ASK1 and TAK1 in Helicobacter pylori-induced cellular responses. PMID: 24082073 Ref: A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROSmediated cAbl/p38 MAPK signaling. PMID: 24121479 Ref: 14-3-3sigma attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells. PMID: 24185104 Ref: Buxus Microphylla var. Koreana Nakai Extract for the Treatment of Gastric Cancer. PMID: 25780674 |
Ref: Underexpressed CNDP2 participates in gastric cancer growth inhibition through activating the MAPK signaling pathway. PMID: 24395568 Ref: Capilliposide C derived from Lysimachia capillipes Hemsl inhibits growth of human prostate cancer PC3 cells by targeting caspase and MAPK pathways. PMID: 24554216 Ref: [Effect of Actinidia chinensis planch polysaccharide on the growth and apoptosis, and p-p38 expression in human gastric cancer SGC-7901 cells]. PMID: 24758086 Ref: Orostachys japonicus induces apoptosis and cell cycle arrest through the mitochondria-dependent apoptotic pathway in AGS human gastric cancer cells. PMID: 24789703 Ref: Oleanolic acid induces apoptosis of MKN28 cells via AKT and JNK signaling pathways. PMID: 24824325 Ref: Transduction motif analysis of gastric cancer based on a human signaling network. PMID: 24838641 Ref: Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFkappaB signaling pathway in gastric cancer cells. PMID: 24929539 Ref: Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-kappaB, and AP-1 signaling pathways. PMID: 25069788 Ref: A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy. PMID: 25146681 Ref: Inhibition of the p38 MAPK pathway sensitizes human gastric cells to doxorubicin treatment in vitro and in vivo. PMID: 25270341 Ref: Heparanase promotes human gastric cancer cells migration and invasion by increasing Src and p38 phosphorylation expression. PMID: 25337202 Ref: 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression. PMID: 25342459 Ref: Inhibition of Vav3 could reverse the drug resistance of gastric cancer cells by downregulating JNK signaling pathway. PMID: 25430880 Ref: Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression. PMID: 25503137 |
Ref: Piperine inhibits IL-1beta-induced IL-6 expression by suppressing p38 MAPK and STAT3 activation in gastric cancer cells. PMID: 25234193 Ref: Schizandra chinensis extracts induce apoptosis in human gastric cancer cells via JNK/p38 MAPK activation and the ROS-mediated/mitochondria-dependent pathway. PMID: 25243868 Ref: Baicalein inhibits the invasion of gastric cancer cells by suppressing the activity of the p38 signaling pathway. PMID: 25502212 Ref: Allicin induces apoptosis of the MGC-803 human gastric carcinoma cell line through the p38 mitogen-activated protein kinase/caspase-3 signaling pathway. PMID: 25523417 Ref: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells. PMID: 25609923 Ref: Ursolic acid inhibits the invasive phenotype of SNU-484 human gastric cancer cells. PMID: 25621065 Ref: FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells. PMID: 25650185 Ref: Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway. PMID: 25727011 Ref: Silencing profilin-1 inhibits gastric cancer progression via integrin beta1/focal adhesion kinase pathway modulation. PMID: 25741138 Ref: Inhibitory effects of Saururus chinensis and its components on stomach cancer cells. PMID: 25765830 Ref: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N PMID: 25767376 Ref: Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis. PMID: 25813526 Ref: CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer. PMID: 25843777 Ref: The roles of BTG3 expression in gastric cancer: a potential marker for carcinogenesis and a target molecule for gene therapy. PMID: 25904053 Ref: Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer. PMID: 25909166 Ref: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. PMID: 25981581 Ref: Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling. PMID: 25998184 Ref: CD97 promotes gastric cancer cell proliferation and invasion through exosome-mediated MAPK signaling pathway. PMID: 26034356 Ref: Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke-induced Gastric Epithelial-Mesenchymal Transition in Mice. PMID: 26074474 Ref: Optimization and Corroboration of the Regulatory Pathway of p42.3 Protein in the Pathogenesis of Gastric Carcinoma. PMID: 26106439 Ref: Targeting Notch signaling by gamma-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer. PMID: 26134677 Ref: Lactotransferrin expression is downregulated and affects the mitogen-activated protein kinase pathway in gastric cancer. PMID: 26137081 Ref: Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation. PMID: 26168048 Ref: Anti-Proliferation Activity of Fucoidan in MKN45 Gastric Cancer Cells and Downregulation of Phosphorylated ASK1, a Cell Cycle-Regulated Kinase. PMID: 26190891 Ref: HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-kappaB activation. PMID: 26259977 Ref: Overexpression of SPAG9 in human gastric cancer is correlated with poor prognosis. PMID: 26293216 Ref: The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-kappaB. PMID: 26371858 Ref: Fermented So-Cheong-Ryong-Tang (FCY) induces apoptosis via the activation of caspases and the regulation of MAPK signaling pathways in cancer cells. PMID: 26403976 Ref: Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathway. PMID: 26497050 Ref: Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. PMID: 26645893 |
Ref: Epstein-Barr Virus (EBV) Tegument Protein BGLF2 Promotes EBV Reactivation through Activation of the p38 Mitogen-Activated Protein Kinase. PMID: 26559845 Ref: The alkyllysophospholipid edelfosine enhances TRAIL-mediated apoptosis in gastric cancer cells through death receptor 5 and the mitochondrial pathway. PMID: 26615420 Ref: Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. PMID: 26774454 Ref: Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells. PMID: 26877709 Ref: Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivo. PMID: 26890145 Ref: Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathway. PMID: 26936198 Ref: PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K/Akt and p38MAPK pathways. PMID: 26968576 Ref: Oleanolic acid induces autophagic death in human gastric cancer cells in vitro and in vivo. PMID: 27079177 Ref: Embelin induces apoptosis of human gastric carcinoma through inhibition of p38 MAPK and NF-kappaB signaling pathways. PMID: 27175982 Ref: MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo. PMID: 27278862 Ref: Ubiquitin-conjugating enzyme UbcH10 promotes gastric cancer growth and is a potential biomarker for gastric cancer. PMID: 27349176 Ref: Gelsolin suppresses gastric cancer metastasis through inhibition of PKR-p38 signaling. PMID: 27419625 Ref: Dihydrotanshinone induces apoptosis of SGC7901 and MGC803 cells via activation of JNK and p38 signalling pathways. PMID: 27431278 Ref: Application of intelligent algorithm in the optimization of novel protein regulatory pathway: Mechanism of action of gastric carcinoma protein p42.3. PMID: 27461626 Ref: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1. PMID: 27529686 Ref: p38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer. PMID: 27588146 Ref: Expression of early growth response gene-1 in precancerous lesions of gastric cancer. PMID: 27698846 Ref: Autophagy Protects from Raddeanin A-Induced Apoptosis in SGC-7901 Human Gastric Cancer Cells. PMID: 27974905 |
Ref: Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells. PMID: 27377703 Ref: Dihydroartemisinin induces apoptosis in human gastric cancer cell line BGC-823 through activation of JNK1/2 and p38 MAPK signaling pathways. PMID: 27401020 Ref: Vascular endothelial growth factor expression is an independent poor prognostic factor for human epidermal growth factor receptor 2 positive gastric cancer. PMID: 27993216 Ref: 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation. PMID: 28076833 Ref: Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment. PMID: 28344324 Ref: Melatonin treatment induces apoptosis through regulating the nuclear factor-kappaB and mitogen-activated protein kinase signaling pathways in human gastric cancer SGC7901 cells. PMID: 28454460 Ref: Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice. PMID: 28501767 Ref: Roles of p38 and JNK protein kinase pathways activated by compound cantharidin capsules containing serum on proliferation inhibition and apoptosis of human gastric cancer cell line. PMID: 28810654 Ref: Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway. PMID: 29344204 Ref: MAEL contributes to gastric cancer progression by promoting ILKAP degradation. PMID: 29371914 Ref: Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells. PMID: 29383168 |
Ref: Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway. PMID: 28983820 Ref: Over-expression of ARHGAP18 suppressed cell proliferation, migration, invasion, and tumor growth in gastric cancer by restraining over-activation of MAPK signaling pathways. PMID: 29386906 Ref: Gastroprotective effects of Hwanglyeonhaedok-tang against Helicobacter pylori-induced gastric cell injury. PMID: 29410309 Ref: Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways. PMID: 29434871 Ref: Ebselen suppresses inflammation induced by Helicobacter pylori lipopolysaccharide via the p38 mitogen-activated protein kinase signaling pathway. PMID: 29488609 Ref: A novel polysaccharide derived from algae extract inhibits cancer progression via JNK, not via the p38 MAPK signaling pathway. PMID: 29512724 Ref: The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma. PMID: 29554921 Ref: CLIC1 Promotes the Progression of Gastric Cancer by Regulating the MAPK/AKT Pathways. PMID: 29669336 Ref: Cancer-adipose tissue interaction and fluid flow synergistically modulate cell kinetics, HER2 expression, and trastuzumab efficacy in gastric cancer. PMID: 29696406 Ref: Blockade of ITGA2 Induces Apoptosis and Inhibits Cell Migration in Gastric Cancer. PMID: 29743821 Ref: Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity. PMID: 29767555 Ref: Anticancer Activity of Phloretin Against Human Gastric Cancer Cell Lines Involves Apoptosis, Cell Cycle Arrest, and Inhibition of Cell Invasion and JNK Signalling Pathway. PMID: 30224626 Ref: Identification of a novel cell cycle-related gene signature predicting survival in patients with gastric cancer. PMID: 30238991 Ref: Toosendanin induces caspase-dependent apoptosis through the p38 MAPK pathway in human gastric cancer cells. PMID: 30245130 Ref: The Elevated ASK1 Expression Inhibits Proliferation and Invasion in Gastric Cancer HGC-27 Cells. PMID: 30324658 Ref: [Aloin induces apoptosis via regulating the activation of MAPKs signaling pathway in human gastric cancer cells in vitro]. PMID: 30377097 |