Primary Site >> Stomach Cancer
Gene >> MAPK1
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Ref: Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells. PMID: 9341140 |
Ref: Oxidative stress activates the human histidine decarboxylase promoter in AGS gastric cancer cells. PMID: 9722530 |
Ref: Critical role of extracellular signal-regulated kinase phosphorylation on menadione (vitamin K3) induced growth inhibition. PMID: 11267961 Ref: Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression. PMID: 11601879 Ref: Resveratrol-induced inactivation of human gastric adenocarcinoma cells through a protein kinase C-mediated mechanism. PMID: 11709203 Ref: Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascade. PMID: 11719466 Ref: MAPK (ERK2) kinase--a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth. PMID: 11758830 |
Ref: EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness. PMID: 12115496 Ref: ras Gene mutations and expression of Ras signal transduction mediators in gastric adenocarcinomas. PMID: 12204060 Ref: Src/ERK but not phospholipase D is involved in keratinocyte growth factor-stimulated secretion of matrix metalloprotease-9 and urokinase-type plasminogen activator in SNU-16 human stomach cancer cell. PMID: 12458339 Ref: [Inhibition of activator protein-1 on the growth of gastric cancer by octreotide]. PMID: 12478891 Ref: MAPK signaling is involved in camptothecin-induced cell death. PMID: 12521296 |
Ref: Effect of inhibition of extracellular signal-regulated kinase 1 and 2 pathway on apoptosis and bcl-2 expression in Helicobacter pylori-infected AGS cells. PMID: 12540563 Ref: Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells. PMID: 12618892 Ref: P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells. PMID: 12883725 Ref: Transcriptional regulation of the human trefoil factor, TFF1, by gastrin. PMID: 12891554 Ref: Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors. PMID: 14531897 Ref: [Roles of ERK1/2 MAPK in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells]. PMID: 14963907 |
Ref: Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. PMID: 14647439 Ref: Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130. PMID: 14699500 Ref: TGF-beta1 (transforming growth factor-beta1)-mediated adhesion of gastric carcinoma cells involves a decrease in Ras/ERKs (extracellular-signal-regulated kinases) cascade activity dependent on c-Src activity. PMID: 14720123 Ref: EGCG blocks tumor promoter-induced MMP-9 expression via suppression of MAPK and AP-1 activation in human gastric AGS cells. PMID: 15161022 Ref: Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. PMID: 15208668 Ref: Decreased expression of the seven ARP2/3 complex genes in human gastric cancers. PMID: 15279900 Ref: Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2. PMID: 15319299 Ref: Regulation of vascular endothelial growth factor expression in human gastric cancer cells by interleukin-1beta. PMID: 15349119 Ref: ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer. PMID: 15367698 |
Ref: Helicobacter-induced intestinal metaplasia in the stomach correlates with Elk-1 and serum response factor induction of villin. PMID: 15576363 Ref: Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer. PMID: 15655810 Ref: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. PMID: 15751984 Ref: Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer. PMID: 15760920 Ref: Extracellular signal-regulated kinase and AP-1 pathways are involved in reactive oxygen species-induced urokinase plasminogen activator receptor expression in human gastric cancer cells. PMID: 15870884 Ref: Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation. PMID: 15882975 Ref: [A study on the regulatory mechanisms of mitogen-activated protein kinase phosphatase-1 in hypoxia inducible factor-1 trans-activation]. PMID: 15949338 Ref: [The function of ERK on Fas-mediated apoptotic signaling pathway of human gastric carcinoma cells]. PMID: 15949415 Ref: PGE2 up-regulates vascular endothelial growth factor expression in MKN28 gastric cancer cells via epidermal growth factor receptor signaling system. PMID: 15995627 Ref: Elevated cyclooxygenase-2 expression in patients with early gastric cancer in the gastric pylorus. PMID: 16082585 Ref: Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells. PMID: 16230373 |
Ref: Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation. PMID: 16183075 Ref: Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines. PMID: 16520550 Ref: Activation of Akt and ERK signalling pathways induced by etoposide confer chemoresistance in gastric cancer cells. PMID: 16527552 Ref: Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation. PMID: 16596182 Ref: Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells. PMID: 16627221 Ref: Erk is involved in the differentiation induced by diallyl disulfide in the human gastric cancer cell line MGC803. PMID: 16874458 Ref: Cellular prion protein promotes invasion and metastasis of gastric cancer. PMID: 16877520 |
Ref: alpha-Tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner. PMID: 16839662 Ref: Interleukin-18 is a critical factor for vascular endothelial growth factor-enhanced migration in human gastric cancer cell lines. PMID: 17001321 Ref: Rebamipide inhibits gastric cancer cell growth. PMID: 17171453 Ref: Hypoxia induced overexpression of PrP(C) in gastric cancer cell lines. PMID: 17387271 Ref: Inhibitory effects of 7-carboxymethyloxy-3',4',5-trimethoxyflavone (DA-6034) on Helicobacter pylori-induced NF-kappa B activation and iNOS expression in AGS cells. PMID: 17404066 Ref: Molecular basis of the differences between normal and tumor tissues of gastric cancer. PMID: 17601708 Ref: 2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer. PMID: 17680560 Ref: Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression. PMID: 17724739 Ref: Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells. PMID: 17823871 Ref: Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells. PMID: 17970088 Ref: Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin. PMID: 18365868 |
Ref: 12-lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway. PMID: 17522976 Ref: Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling. PMID: 18081943 Ref: Trastuzumab inhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cisplatin. PMID: 18097546 Ref: Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. PMID: 18258606 Ref: Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells. PMID: 18339873 Ref: Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. PMID: 18395088 Ref: Biology of intestinal metaplasia in 2008: more than a simple phenotypic alteration. PMID: 18400571 Ref: Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells. PMID: 18619958 Ref: Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. PMID: 18805435 Ref: EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-kappaB signaling in human gastric carcinoma cells. PMID: 19020743 Ref: Role of TMPRSS4 during cancer progression. PMID: 19034347 |
Ref: Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells. PMID: 18829155 Ref: Proliferative effects of gamma-aminobutyric acid on the gastric cancer cell line are associated with extracellular signal-regulated kinase 1/2 activation. PMID: 19032445 Ref: Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells. PMID: 19140230 Ref: Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer. PMID: 19142899 Ref: Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer. PMID: 19148483 Ref: Eupatilin exhibits a novel anti-tumor activity through the induction of cell cycle arrest and differentiation of gastric carcinoma AGS cells. PMID: 19281788 Ref: Breast cancer resistance protein/ABCG2 is differentially regulated downstream of extracellular signal-regulated kinase. PMID: 19514121 Ref: TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways. PMID: 19657566 Ref: AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer. PMID: 19723882 Ref: Kiss-1 suppresses MMP-9 expression by activating p38 MAP kinase in human stomach cancer. PMID: 20066900 |
Ref: Vascular endothelial growth factor (VEGF) enhances gastric carcinoma invasiveness via integrin alpha(v)beta6. PMID: 19581046 Ref: Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells. PMID: 19856312 Ref: ERK/MAPK activation involves hypoxia-induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer. PMID: 19998339 Ref: Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth. PMID: 20061081 Ref: Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation. PMID: 20198349 Ref: Intracellular chloride regulates cell proliferation through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells. PMID: 20205250 Ref: Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. PMID: 20348091 Ref: Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition. PMID: 20406949 Ref: Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages. PMID: 20410304 Ref: Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines. PMID: 20428833 Ref: gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line. PMID: 20452389 Ref: Down-regulation of human epidermal growth factor receptor 2/neu oncogene by corosolic acid induces cell cycle arrest and apoptosis in NCI-N87 human gastric cancer cells. PMID: 20522955 Ref: Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. PMID: 20804754 Ref: [Effects of EGFR inhibitor AG1478 in combination with celecoxib on the growth of gastric cancer cells]. PMID: 20848776 Ref: Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer. PMID: 20878069 Ref: CADPE inhibits PMA-stimulated gastric carcinoma cell invasion and matrix metalloproteinase-9 expression by FAK/MEK/ERK-mediated AP-1 activation. PMID: 21047770 Ref: Hepatoma-derived growth factor regulates the bad-mediated apoptotic pathway and induction of vascular endothelial growth factor in stomach cancer cells. PMID: 21302807 Ref: Phosphoinositide 3-kinase/Akt and nuclear factor kappaB pathways are involved in tumor necrosis factor-related apoptosis-inducing ligand resistance in human gastric cancer cells. PMID: 21472268 |
Ref: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways. PMID: 20498032 Ref: Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells. PMID: 20799280 Ref: MSP-induced RON activation upregulates uPAR expression and cell invasiveness via MAPK, AP-1 and NF-kappaB signals in gastric cancer cells. PMID: 21081472 Ref: Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer. PMID: 21170990 Ref: Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. PMID: 21287681 Ref: Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. PMID: 21346147 Ref: Metastatic function of BMP-2 in gastric cancer cells: the role of PI3K/AKT, MAPK, the NF-kappaB pathway, and MMP-9 expression. PMID: 21570392 Ref: Stanniocalcin-1 promotes tumor angiogenesis through up-regulation of VEGF in gastric cancer cells. PMID: 21672207 Ref: Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study. PMID: 21698158 Ref: Interferon-alpha sensitizes human gastric cancer cells to TRAIL-induced apoptosis via activation of the c-CBL-dependent MAPK/ERK pathway. PMID: 21725207 Ref: Co-expression of erythropoietin receptor with human epidermal growth factor 2 may counteract trastuzumab inhibition in gastric cancer. PMID: 21944379 |
Ref: Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells. PMID: 21676900 Ref: Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells. PMID: 22012247 Ref: Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer. PMID: 22135232 Ref: Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10. PMID: 22285823 Ref: E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells. PMID: 22322152 Ref: Regulation of SHP2 by PTEN/AKT/GSK-3beta signaling facilitates IFN-gamma resistance in hyperproliferating gastric cancer. PMID: 22325465 Ref: Regulation of glycogen synthase kinase-3 by thymosin beta-4 is associated with gastric cancer cell migration. PMID: 22328534 Ref: Prognostic value of RKIP and p-ERK in gastric cancer. PMID: 22463874 Ref: Midkine confers Adriamycin resistance in human gastric cancer cells. PMID: 22576950 Ref: Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis. PMID: 22634261 Ref: Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer. PMID: 22672288 Ref: ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-kappaB-dependent and Notch-independent mechanism. PMID: 22781708 Ref: Pro-apoptotic role of the MEK/ERK pathway in ursodeoxycholic acid-induced apoptosis in SNU601 gastric cancer cells. PMID: 22824956 Ref: beta,beta-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells. PMID: 22848597 Ref: [Mechanisms of (2-methyl-n-butyl) shikonin induced apoptosis of gastric cancer SGC-7901 cells]. PMID: 22919733 Ref: Type II cGMP-dependent protein kinase inhibits ERK/JNK-mediated activation of transcription factors in gastric cancer cells. PMID: 22940826 Ref: Protease-activated receptor-2 induces expression of vascular endothelial growth factor and cyclooxygenase-2 via the mitogen-activated protein kinase pathway in gastric cancer cells. PMID: 22941376 Ref: Protein inhibitor of activated STAT-1 is downregulated in gastric cancer tissue and involved in cell metastasis. PMID: 22972521 Ref: Crosstalk between EGFR and integrin affects invasion and proliferation of gastric cancer cell line, SGC7901. PMID: 23109808 Ref: MiR-378 inhibits progression of human gastric cancer MGC-803 cells by targeting MAPK1 in vitro. PMID: 24139413 |
Ref: Semaphorin 5A, an axon guidance molecule, enhances the invasion and metastasis of human gastric cancer through activation of MMP9. PMID: 22821546 Ref: Preclinical evaluation of a novel c-Met inhibitor in a gastric cancer xenograft model using small animal PET. PMID: 22864665 Ref: RKIP and 14-3-3epsilon exert an opposite effect on human gastric cancer cells SGC7901 by regulating the ERK/MAPK pathway differently. PMID: 22899242 Ref: CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway. PMID: 23070808 Ref: Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance. PMID: 23165320 Ref: Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. PMID: 23415900 Ref: RNAimediated knockdown of PRL3 inhibits cell invasion and downregulates ERK 1/2 expression in the human gastric cancer cell line, SGC7901. PMID: 23589069 Ref: Cannabinoid receptor agonist as an alternative drug in 5-fluorouracil-resistant gastric cancer cells. PMID: 23749906 Ref: Combination treatment of PD98059 and DAPT in gastric cancer through induction of apoptosis and downregulation of WNT/beta-catenin. PMID: 23792588 Ref: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer. PMID: 23803691 Ref: ERK1/2 signalling pathway is involved in CD147-mediated gastric cancer cell line SGC7901 proliferation and invasion. PMID: 23828593 Ref: Association between phosphorylated AMP-activated protein kinase and MAPK3/1 expression and prognosis for patients with gastric cancer. PMID: 23860205 Ref: Ribonucleotide reductase large subunit M1 predicts poor survival due to modulation of proliferative and invasive ability of gastric cancer. PMID: 23922955 Ref: Hepatocyte growth factor-mediated gastrin-releasing peptide induces IL-8 expression through Ets-1 in gastric cancer cells. PMID: 23924923 Ref: Interferon-alpha enhances 5'-deoxy-5-fluorouridine-induced apoptosis by ERK-dependant upregulation of thymidine phosphorylase. PMID: 24027750 Ref: Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness. PMID: 24104608 Ref: 14-3-3sigma attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells. PMID: 24185104 Ref: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway. PMID: 24241351 Ref: Cbl-b enhances sensitivity to 5-fluorouracil via EGFR- and mitochondria-mediated pathways in gastric cancer cells. PMID: 24351824 |
Ref: Overexpression of L1CAM is associated with tumor progression and prognosis via ERK signaling in gastric cancer. PMID: 24046108 Ref: ERK1/2 inhibition enhances apoptosis induced by JAK2 silencing in human gastric cancer SGC7901 cells. PMID: 24178240 Ref: Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target. PMID: 24253382 Ref: Increased serum chemerin level promotes cellular invasiveness in gastric cancer: a clinical and experimental study. PMID: 24274970 Ref: Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells. PMID: 24337453 Ref: Underexpressed CNDP2 participates in gastric cancer growth inhibition through activating the MAPK signaling pathway. PMID: 24395568 Ref: The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway. PMID: 24416349 Ref: The niche component periostin is produced by cancer-associated fibroblasts, supporting growth of gastric cancer through ERK activation. PMID: 24418260 Ref: Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer. PMID: 24465527 Ref: RASAL1 influences the proliferation and invasion of gastric cancer cells by regulating the RAS/ERK signaling pathway. PMID: 24531877 Ref: Low expression of ERK signaling pathway affecting proliferation, cell cycle arrest and apoptosis of human gastric HGC-27 cells line. PMID: 24554029 Ref: 1,25-Dihydroxyvitamin D(3) and cisplatin synergistically induce apoptosis and cell cycle arrest in gastric cancer cells. PMID: 24573222 Ref: Genistein-inhibited cancer stem cell-like properties and reduced chemoresistance of gastric cancer. PMID: 24573253 Ref: IL-1beta-stimulated urokinase plasminogen activator expression through NF-kappaB in gastric cancer after HGF treatment. PMID: 24626561 Ref: Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. PMID: 24647664 Ref: MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression. PMID: 24736504 Ref: Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer. PMID: 24757178 Ref: AKT/ERK activation is associated with gastric cancer cell resistance to paclitaxel. PMID: 24817940 Ref: Oleanolic acid induces apoptosis of MKN28 cells via AKT and JNK signaling pathways. PMID: 24824325 Ref: Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-kappaB pathway. PMID: 24824968 Ref: IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling. PMID: 24937671 Ref: CDX2 can be regulated through the signalling pathways activated by IL-6 in gastric cells. PMID: 24953186 Ref: FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival. PMID: 24968263 Ref: Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-kappaB, and AP-1 signaling pathways. PMID: 25069788 Ref: Inhibition of epidermal growth factor receptor signaling prohibits metastasis of gastric cancer via downregulation of MMP7 and MMP13. PMID: 25085584 Ref: Sorafenib regulating ERK signals pathway in gastric cancer cell. PMID: 25136776 Ref: A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy. PMID: 25146681 Ref: Rabeprazole exhibits antiproliferative effects on human gastric cancer cell lines. PMID: 25202402 Ref: Enhanced expression of long noncoding RNA CARLo-5 is associated with the development of gastric cancer. PMID: 25674211 Ref: PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways. PMID: 27919028 |
Ref: Pb2+ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells. PMID: 23765435 Ref: OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer. PMID: 24717932 Ref: Bone morphogenetic protein 2 mediates epithelial-mesenchymal transition via AKT and ERK signaling pathways in gastric cancer. PMID: 25448881 Ref: Ras/ERK signaling pathway is involved in curcumin-induced cell cycle arrest and apoptosis in human gastric carcinoma AGS cells. PMID: 25492214 Ref: Orexin A upregulates the protein expression of OX1R and enhances the proliferation of SGC-7901 gastric cancer cells through the ERK signaling pathway. PMID: 25515760 Ref: CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in gastric cancer. PMID: 25572817 Ref: Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer. PMID: 25638174 Ref: FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells. PMID: 25650185 Ref: Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2. PMID: 25652880 Ref: Asporin participates in gastric cancer cell growth and migration by influencing EGF receptor signaling. PMID: 25673058 Ref: G-protein coupled receptor 34 knockdown impairs the proliferation and migration of HGC-27 gastric cancer cells in vitro. PMID: 25673461 Ref: Activation of matrix metalloproteinase-9 (MMP-9) by neurotensin promotes cell invasion and migration through ERK pathway in gastric cancer. PMID: 25724188 Ref: Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway. PMID: 25727011 Ref: RASAL1 attenuates gastric carcinogenesis in nude mice by blocking RAS/ERK signaling. PMID: 25735335 Ref: Silencing profilin-1 inhibits gastric cancer progression via integrin beta1/focal adhesion kinase pathway modulation. PMID: 25741138 Ref: Hyperglycemia Promotes Human Gastric Carcinoma Progression via Aquaporin 3. PMID: 25777259 Ref: EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells. PMID: 25779663 Ref: Chrysin inhibits tumor promoter-induced MMP-9 expression by blocking AP-1 via suppression of ERK and JNK pathways in gastric cancer cells. PMID: 25875631 Ref: Antitumor effect and apoptosis induction of Alocasia cucullata (Lour.) G. Don in human gastric cancer cells in vitro and in vivo. PMID: 25888009 Ref: Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer. PMID: 25909166 Ref: Ginkgo biloba extract enhances chemotherapy sensitivity and reverses chemoresistance through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer cells. PMID: 25962735 Ref: Myeloid cell leukemia-1 promotes epithelial-mesenchymal transition of human gastric cancer cells. PMID: 26058661 Ref: Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke-induced Gastric Epithelial-Mesenchymal Transition in Mice. PMID: 26074474 Ref: Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer. PMID: 26091251 Ref: Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro. PMID: 26111180 Ref: Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas. PMID: 26147886 Ref: MicroRNA197 reverses the drug resistance of fluorouracilinduced SGC7901 cells by targeting mitogenactivated protein kinase 1. PMID: 26151540 Ref: Cortactin promotes colon cancer progression by regulating ERK pathway. PMID: 26151562 Ref: Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase. PMID: 26171055 Ref: Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells. PMID: 26171059 Ref: Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the beta-Catenin Pathway. PMID: 26226629 Ref: WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-gamma pathways. PMID: 26291058 Ref: Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas. PMID: 26296355 Ref: TSPAN8 promotes gastric cancer growth and metastasis via ERK MAPK pathway. PMID: 26309511 Ref: The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-kappaB. PMID: 26371858 Ref: [Effects of beta-elemene on proliferation and apoptosis of SGC7901 gastric cancer cells in vitro and the underlying mechanisms]. PMID: 26403730 Ref: Fermented So-Cheong-Ryong-Tang (FCY) induces apoptosis via the activation of caspases and the regulation of MAPK signaling pathways in cancer cells. PMID: 26403976 Ref: Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues. PMID: 26435392 Ref: Downregulation of P-gp, Ras and p-ERK1/2 contributes to the arsenic trioxide-induced reduction in drug resistance towards doxorubicin in gastric cancer cell lines. PMID: 26459009 Ref: DBD-F induces apoptosis in gastric cancer-derived cells through suppressing HIF2alpha expression. PMID: 26526811 Ref: Cytotoxic effects of beta-carboline alkaloids on human gastric cancer SGC-7901 cells. PMID: 26550217 Ref: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer. PMID: 26567773 Ref: Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. PMID: 26645893 Ref: Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand. PMID: 26788199 |
Ref: Decreased expression of long non-coding RNA WT1-AS promotes cell proliferation and invasion in gastric cancer. PMID: 26449525 Ref: Astaxanthin Inhibits Proliferation of Human Gastric Cancer Cell Lines by Interrupting Cell Cycle Progression. PMID: 26470770 Ref: All-trans retinoic acid protects against doxorubicin-induced cardiotoxicity by activating the ERK2 signalling pathway. PMID: 26507774 Ref: Sustained ERK activation-mediated proliferation inhibition of farrerol on human gastric carcinoma cell line by G0/G1-phase cell-cycle arrest. PMID: 26656929 Ref: Inhibition of Vav3 gene can promote apoptosis of human gastric cancer cell line MGC803 by regulating ERK pathway. PMID: 26695150 Ref: Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. PMID: 26716415 Ref: DCT015, a new sorafenib derivate, inhibits tumor growth and angiogenesis in gastric cancer models. PMID: 26768619 Ref: Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer. PMID: 26769843 Ref: Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. PMID: 26774454 Ref: Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells. PMID: 26801760 Ref: Helicobacter pylori induces Snail expression through ROS-mediated activation of Erk and inactivation of GSK-3beta in human gastric cancer cells. PMID: 26808296 Ref: Lentivirus-mediated PLCgamma1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma. PMID: 26811493 Ref: CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells. PMID: 26830684 Ref: Trichostatin A potentiates TRAIL-induced antitumor effects via inhibition of ERK/FOXM1 pathway in gastric cancer. 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