Primary Site >> Colorectal Cancer
Gene >> MAP3K5
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Ref: Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1. PMID: 17342315 |
Ref: LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. PMID: 18794113 |
Ref: Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways. PMID: 19038304 |
Ref: A 'metastasis-prone' signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics. PMID: 20143136 Ref: ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells. PMID: 20512919 |
Ref: p34 (SEI-1) inhibits ROS-induced cell death through suppression of ASK1. PMID: 21725208 |
Ref: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. PMID: 23712032 |
Ref: Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system. PMID: 25173814 Ref: Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells. PMID: 25289048 |
Ref: Screening of potential diagnostic markers and therapeutic targets against colorectal cancer. PMID: 26185457 |
Ref: Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway. PMID: 27323852 |
Ref: ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis. PMID: 28931753 |
Ref: Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression. PMID: 29940575 |