Primary Site >> Colorectal Cancer
Gene >> MAP2K6
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Ref: Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death. PMID: 14749540 Ref: p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. PMID: 15037631 |
Ref: PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation. PMID: 17640974 |
Ref: P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance. PMID: 21841826 |
Ref: MKK6 is upregulated in human esophageal, stomach, and colon cancers. PMID: 25019214 |
Ref: Loss-of-function uORF mutations in human malignancies. PMID: 29402903 Ref: MiR-422a targets MAPKK6 and regulates cell growth and apoptosis in colorectal cancer cells. PMID: 29566993 |