Primary Site >> Colorectal Cancer

Gene >> MAP2K3

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Ref: Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades.
PMID: 11085935
Ref: Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
PMID: 11980910
Ref: Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
PMID: 14749540
Ref: Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK.
PMID: 15078890
Ref: MAP kinases in proliferating human colon cancer Caco-2 cells.
PMID: 19301097
Ref: P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance.
PMID: 21841826
Ref: The synthetic flavonoid WYC02-9 inhibits colorectal cancer cell growth through ROS-mediated activation of MAPK14 pathway.
PMID: 23624232
Ref: Differential Gene Expression in Colon Tissue Associated With Diet, Lifestyle, and Related Oxidative Stress.
PMID: 26230583
Ref: Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness.
PMID: 26232912
Ref: PKCalpha in colon cancer cells promotes M1 macrophage polarization via MKK3/6-P38 MAPK pathway.
PMID: 29637628