Primary Site >> Colorectal Cancer

Gene >> LYN

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Ref: c-Yes tyrosine kinase activity in human colon carcinoma.
PMID: 7690925
Ref: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.
PMID: 10521789
Ref: A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells.
PMID: 11431370
Ref: Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells.
PMID: 16094635
Ref: CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation.
PMID: 17599831
Ref: A cholesterol-independent membrane microdomain serves as a functional counter-receptor for E-selectin at the Colo201 cell surface and initiates signalling on E-selectin binding.
PMID: 17684030
Ref: Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer.
PMID: 19359472
Ref: Gene-specific methylation: potential markers for colorectal cancer.
PMID: 19404924
Ref: A five-gene signature as a potential predictor of metastasis and survival in colorectal cancer.
PMID: 20077526
Ref: Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
PMID: 21670084
Ref: Predicting ulcerative colitis-associated colorectal cancer using reverse-transcription polymerase chain reaction analysis.
PMID: 21859567
Ref: Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer.
PMID: 22731636
Ref: [Expression profile of genes associated with the histaminergic system estimated by oligonucleotide microarray analysis HG-U133A in women with endometrial adenocarcinoma].
PMID: 24783427
Ref: Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis.
PMID: 25823815
Ref: Quantitative Profiling of Protein Tyrosine Kinases in Human Cancer Cell Lines by Multiplexed Parallel Reaction Monitoring Assays.
PMID: 26631510
Ref: Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
PMID: 28819788
Ref: The NF-kappaB signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression.
PMID: 29188362