Primary Site >> Pancreatic Cancer

Gene >> LTB4R2

  • 2002
  • 2005
  • 2008
  • 2012
  • 2016
Ref: Leukotriene B4 receptor antagonist LY293111 inhibits proliferation and induces apoptosis in human pancreatic cancer cells.
PMID: 12374694
Ref: A novel anti-pancreatic cancer agent, LY293111.
PMID: 15846111
Ref: BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation.
PMID: 18781173
Ref: Novel involvement of leukotriene B(4) receptor 2 through ERK activation by PP2A down-regulation in leukotriene B(4)-induced keratin phosphorylation and reorganization of pancreatic cancer cells.
PMID: 23017243
Ref: Leukotriene B4 induces EMT and vimentin expression in PANC-1 pancreatic cancer cells: Involvement of BLT2 via ERK2 activation.
PMID: 27914516