Primary Site >> Colorectal Cancer

Gene >> LOXL2

  • 2007
  • 2008
  • 2009
  • 2015
  • 2017
  • 2018
Ref: Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
PMID: 17394133
Ref: Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
PMID: 18590575
Ref: TIMP-1 expression in human colorectal cancer is associated with TGF-B1, LOXL2, INHBA1, TNF-AIP6 and TIMP-2 transcript profiles.
PMID: 19383344
Ref: Differential expression of the LOX family genes in human colorectal adenocarcinomas.
PMID: 19724858
Ref: LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.
PMID: 26206869
Ref: A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma.
PMID: 28246207
Ref: Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis.
PMID: 29113306
Ref: Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer.
PMID: 29845296