Primary Site >> Colorectal Cancer
Gene >> LIMK2
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Ref: A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability. PMID: 22883572 |
Ref: Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation. PMID: 23585469 |
Ref: A proteomics approach to identifying novel protein targets involved in erinacine A-mediated inhibition of colorectal cancer cells' aggressiveness. PMID: 27709782 |
Ref: LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance. PMID: 29352327 Ref: Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting beta-catenin nuclear translocation. PMID: 29970879 Ref: Cofilin-1 signaling mediates epithelial-mesenchymal transition by promoting actin cytoskeleton reorganization and cell-cell adhesion regulation in colorectal cancer cells. PMID: 30296500 |