Primary Site >> Colorectal Cancer

Gene >> LIG4

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Ref: Atm is a negative regulator of intestinal neoplasia.
PMID: 17700532
Ref: DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome.
PMID: 21974800
Ref: A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining.
PMID: 23752193
Ref: Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer.
PMID: 24282031
Ref: [Mechanism of radiotherapy sensitization of curcumin on rectal cancer cells].
PMID: 26108778
Ref: LIG4 mediates Wnt signalling-induced radioresistance.
PMID: 27009971
Ref: [Study of the effect of LIG4 on the radiosensitivity enhancement of rectal cancer cells by curcumin].
PMID: 28000198
Ref: Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes.
PMID: 29277765