Primary Site >> Stomach Cancer

Gene >> LEPR

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Ref: Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.
PMID: 16230373
Ref: Possible involvement of leptin and leptin receptor in developing gastric adenocarcinoma.
PMID: 16437696
Ref: Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer.
PMID: 17006991
Ref: [Quercetin affects leptin and its receptor in human gastric cancer MGC-803 cells and JAK-STAT pathway].
PMID: 22230496
Ref: Susceptibility of gastric cancer according to leptin and leptin receptor gene polymorphisms in Korea.
PMID: 22792528
Ref: Recombinant human leptin induces growth inhibition and apoptosis in human gastric cancer MGC-803 cells.
PMID: 23001141
Ref: Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice.
PMID: 23178499
Ref: Association of LEPR K109R polymorphisms with cancer risk: a systematic review and pooled analysis.
PMID: 25261678
Ref: Leptin receptor signaling is required for high-fat diet-induced atrophic gastritis in mice.
PMID: 26839577
Ref: High-fat diet feeding promotes stemness and precancerous changes in murine gastric mucosa mediated by leptin receptor signaling pathway.
PMID: 27693038