Primary Site >> Colorectal Cancer
Gene >> KRT18
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Ref: [A study of the antineoplastic activity of K18]. PMID: 2423038 |
Ref: The inhibitory effect of a conjugate of human immunoglobulin G and melphalan, K18, on DNA synthesis of human tumor cells. PMID: 2475050 |
Ref: Increased expression of cytokeratin and ferritin-H genes in tumorigenic clones of the SW 613-S human colon carcinoma cell line. PMID: 1377134 |
Ref: Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas. PMID: 7504281 |
Ref: An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line. PMID: 7537848 Ref: Micrometastases in bone marrow of patients undergoing "curative" surgery for gastrointestinal cancer. PMID: 7557136 Ref: Tumour diagnosis by PCR-based detection of tumour cells. PMID: 7652485 |
Ref: Molecular cytogenetic analysis of cytokeratin 20-labeled cells in primary tumors and bone marrow aspirates from colorectal carcinoma patients. PMID: 9128980 |
Ref: Transcriptional mechanisms responsible for the overexpression of the keratin 18 gene in cells of a human colon carcinoma cell line. PMID: 10094831 Ref: Deregulated expression of the keratin 18 gene in human colon carcinoma cells. PMID: 11586789 |
Ref: Cancer-associated cleavage of cytokeratin 8/18 heterotypic complexes exposes a neoepitope in human adenocarcinomas. PMID: 11923318 Ref: Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism. PMID: 12140315 |
Ref: Use of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1. PMID: 15831101 Ref: [Usefulness of evaluation of carcinoembryonic antigen (CEA) and soluble fragments of cytokeratin 18-th (TPS) in postoperative monitoring of patients with colorectal cancer]. PMID: 16124375 |
Ref: Increased colorectal epithelial cell proliferation and crypt fission associated with obesity and roux-en-Y gastric bypass. PMID: 18559555 |
Ref: Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients. PMID: 19254831 Ref: Circulating cell death products predict clinical outcome of colorectal cancer patients. PMID: 19302716 |
Ref: New insights into the development and differentiation of the human anorectal epithelia. Are there clinical consequences? PMID: 20563874 |
Ref: Keratins in colorectal epithelial function and disease. PMID: 22974212 Ref: Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer. PMID: 22996610 |
Ref: Maslinic acid, a triterpenic anti-tumoural agent, interferes with cytoskeleton protein expression in HT29 human colon-cancer cells. PMID: 23499989 |
Ref: Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma. PMID: 25423035 |
Ref: [Keratin 18 phosphorylation increases autophagy of colorectal cancer HCT116 cells and enhanced its sensitivity to oxaliplatin]. PMID: 26728375 Ref: Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway. PMID: 27234655 Ref: Keratins Are Altered in Intestinal Disease-Related Stress Responses. PMID: 27626448 |
Ref: SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer. PMID: 29456503 |