Primary Site >> Colorectal Cancer

Gene >> KNG1

  • 1998
  • 2000
  • 2007
  • 2013
  • 2014
  • 2017
Ref: A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a Gq/11 protein, phosphatidylinositol 3-kinase beta, and protein kinase Cepsilon.
PMID: 9822674
Ref: In various tumour cell lines the peptide bradykinin B(2) receptor antagonist, Hoe 140 (Icatibant), may act as mitogenic agonist.
PMID: 11139431
Ref: An investigation on the nature of the peptide at m/z 904, overexpressed in plasma of patients with colorectal cancer and familial adenomatous polyposis.
PMID: 18085540
Ref: Identification of kininogen-1 as a serum biomarker for the early detection of advanced colorectal adenoma and colorectal cancer.
PMID: 23894665
Ref: Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells.
PMID: 25109623
Ref: OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages.
PMID: 28344541
Ref: A multidimensional integration analysis reveals potential bridging targets in the process of colorectal cancer liver metastasis.
PMID: 28628609