Primary Site >> Colorectal Cancer
Gene >> KMT2C
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Ref: Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma. PMID: 17440062 |
Ref: Low frequency of MLL3 mutations in colorectal carcinoma. PMID: 19215798 |
Ref: Distinct genetic alterations in colorectal cancer. PMID: 20126641 |
Ref: Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer. PMID: 21853109 Ref: Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. PMID: 22014273 |
Ref: Exome sequencing identifies an MLL3 gene germ line mutation in a pedigree of colorectal cancer and acute myeloid leukemia. PMID: 23429989 |
Ref: Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors. PMID: 24706189 Ref: Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer. PMID: 24755471 |
Ref: RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies. PMID: 26350096 Ref: Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes. PMID: 26620301 Ref: Colorectal Cancer Genetic Heterogeneity Delineated by Multi-Region Sequencing. PMID: 27023146 Ref: Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants. PMID: 27260798 Ref: Aberrant DNA methylation of acute myeloid leukemia and colorectal cancer in a Chinese pedigree with a MLL3 germline mutation. PMID: 27405564 |
Ref: Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. PMID: 28524162 Ref: Uncommon somatic mutations in metastatic NUT midline carcinoma. PMID: 28967088 |
Ref: Clonal Structures of Regionally Synchronous Gastric Adenomas and Carcinomas. PMID: 29945994 Ref: Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4. PMID: 29954944 Ref: Impact of Patient Age on Molecular Alterations of Left-Sided Colorectal Tumors. PMID: 30018131 |