Primary Site >> Colorectal Cancer
Gene >> KMT2B
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Ref: The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. PMID: 16510874 |
Ref: Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon. PMID: 20433758 |
Ref: Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo. PMID: 22713656 |
Ref: Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. PMID: 28524162 Ref: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer. PMID: 28672935 |
Ref: Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4. PMID: 29954944 |