Primary Site >> Pancreatic Cancer

Gene >> KMT2A

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Ref: MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines.
PMID: 10637508
Ref: Human FOX gene family (Review).
PMID: 15492844
Ref: Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
PMID: 20442285
Ref: Human RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancer.
PMID: 22046413
Ref: The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration.
PMID: 25912306
Ref: Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients.
PMID: 26154128
Ref: In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.
PMID: 27320920
Ref: The MLL1-H3K4me3 Axis-Mediated PD-L1 Expression and Pancreatic Cancer Immune Evasion.
PMID: 28131992