Primary Site >> Colorectal Cancer

Gene >> KLRC1

  • 2004
  • 2008
  • 2009
  • 2011
  • 2012
  • 2013
  • 2016
Ref: Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients.
PMID: 15187109
Ref: Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells.
PMID: 18759005
Ref: Cetuximab-mediated cellular cytotoxicity is inhibited by HLA-E membrane expression in colon cancer cells.
PMID: 19318419
Ref: High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis.
PMID: 22032294
Ref: HLA-E/beta2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression.
PMID: 21953582
Ref: Possible association of decreased NKG2D expression levels and suppression of the activity of natural killer cells in patients with colorectal cancer.
PMID: 22200673
Ref: Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer.
PMID: 24138752
Ref: Phenotypic and Functional Dysregulated Blood NK Cells in Colorectal Cancer Patients Can Be Activated by Cetuximab Plus IL-2 or IL-15.
PMID: 27777574