Primary Site >> Pancreatic Cancer

Gene >> KLF4

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Ref: The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1.
PMID: 10859317
Ref: Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.
PMID: 15753353
Ref: 2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells.
PMID: 17724373
Ref: Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells.
PMID: 18559508
Ref: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
PMID: 19935649
Ref: Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells.
PMID: 19823826
Ref: KLF4alpha up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer.
PMID: 20727893
Ref: KLF4 is a novel candidate tumor suppressor gene in pancreatic ductal carcinoma.
PMID: 21224073
Ref: A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4.
PMID: 22750490
Ref: Requirement of NEMO/IKKgamma for effective expansion of KRAS-induced precancerous lesions in the pancreas.
PMID: 22751123
Ref: Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer.
PMID: 23598278
Ref: DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.
PMID: 24040120
Ref: microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-beta actions.
PMID: 24096486
Ref: XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
PMID: 24880079
Ref: A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer.
PMID: 24947925
Ref: Susceptibility of pancreatic cancer stem cells to reprogramming.
PMID: 18854834
Ref: Susceptibility of pancreatic cancer stem cells to reprogramming.
PMID: 25849272
Ref: Susceptibility of pancreatic cancer stem cells to reprogramming.
PMID: 26298849
Ref: p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling.
PMID: 26546043
Ref: KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis.
PMID: 26880805
Ref: KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis.
PMID: 26977883
Ref: Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker.
PMID: 27472393
Ref: The Novel KLF4/MSI2 Signaling Pathway Regulates Growth and Metastasis of Pancreatic Cancer.
PMID: 27449499
Ref: DNA-Methyltransferase 1 Induces Dedifferentiation of Pancreatic Cancer Cells through Silencing of Kruppel-Like Factor 4 Expression.
PMID: 28659310
Ref: Kruppel-Like Factor 4 Inhibits Pancreatic Cancer Epithelial-to-Mesenchymal Transition and Metastasis by Down-Regulating Caveolin-1 Expression.
PMID: 29587259
Ref: Chronic ethanol exposure of human pancreatic normal ductal epithelial cells induces cancer stem cell phenotype through SATB2.
PMID: 29761897