Primary Site >> Liver Cancer
Gene >> KLB
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Ref: Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma. PMID: 22439738 |
Ref: Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19. PMID: 24728076 |
Ref: First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway. PMID: 25776529 Ref: Paralog-Specific Kinase Inhibition of FGFR4: Adding to the Arsenal of Anti-FGFR Agents. PMID: 25847957 |
Ref: Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis. PMID: 28249259 Ref: Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma. PMID: 28445152 Ref: Downregulation of klotho beta is associated with invasive ductal carcinoma progression. PMID: 29344186 |
Ref: Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation. PMID: 29432567 |