Primary Site >> Pancreatic Cancer
Gene >> KEAP1
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Ref: Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy. PMID: 21489257 Ref: Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. PMID: 21734707 |
Ref: PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. PMID: 22331464 |
Ref: Clinicopathological characteristics of anaplastic carcinoma of the pancreas with rhabdoid features. PMID: 25031015 |
Ref: Keap1 expression has independent prognostic value in pancreatic adenocarcinomas. PMID: 25879528 Ref: Keap1-Nrf2 signalling in pancreatic cancer. PMID: 26117456 |
Ref: UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis. PMID: 26497117 Ref: MBD1 is an Epigenetic Regulator of KEAP1 in Pancreatic Cancer. PMID: 26980696 Ref: Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1. PMID: 27756327 |
Ref: Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis. PMID: 29240881 |
Ref: Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma. PMID: 28971839 |