Primary Site >> Liver Cancer
Gene >> KDR
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Ref: A novel gene delivery system targeting cells expressing VEGF receptors. PMID: 10321685 Ref: KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in murine hepatocellular carcinoma cells. PMID: 10534339 |
Ref: Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues. PMID: 10854533 Ref: Angiogenesis of liver metastases: role of sinusoidal endothelial cells. PMID: 10910247 Ref: Detection of vascular endothelial growth factor and its receptor expression in human hepatocellular carcinoma biopsy specimens. PMID: 10921418 Ref: [The effects of the expression of VEGF and KDR on the angiogenesis, growth and metastasis of hepatocellular carcinoma]. PMID: 11832083 |
Ref: Dual mechanism of vascular endothelial growth factor upregulation by hypoxia in human hepatocellular carcinoma. PMID: 11115828 Ref: The vascular endothelial growth factor receptor KDR/Flk-1 is a major regulator of malignant ascites formation in the mouse hepatocellular carcinoma model. PMID: 11283848 Ref: Induction of angiogenesis by expression of soluble type II transforming growth factor-beta receptor in mouse hepatoma. PMID: 11457844 Ref: Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma. PMID: 11764072 |
Ref: Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma. PMID: 11915029 Ref: Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice. PMID: 12464871 |
Ref: The molecular mechanism underlying angiogenesis in hepatocellular carcinoma: the imbalance activation of signaling pathways. PMID: 14627514 |
Ref: Inhibition of cytokine-induced microvascular arrest of tumor cells by recombinant endostatin prevents experimental hepatic melanoma metastasis. PMID: 14729638 Ref: [The specific cytotoxic effect of tumor infiltrating lymphocytes transfected with chimeric T cell receptor on cells which express KDR]. PMID: 15059323 Ref: Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. PMID: 15185292 Ref: [The effect of pro-angiogenic factors and their receptors on angiogenesis in hepatocellular carcinoma]. PMID: 15555336 Ref: [Construction of a DNA vaccine against extracellular domain 1-3 of Flk1 and its inhibitory effect on growth of liver cancer cell line H22]. PMID: 15601548 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-quantum dot-vascular endothelial growth factor PMID: 20641777 Ref: Anti-vascular endothelial growth factor polylactic acid-polyethylene glycol-poly-L-Lys/gadolinium-diethylenetriamine pentaacetic acid nanoparticles PMID: 22812022 |
Ref: Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone), a component from Chinese herbal medicine. PMID: 15703376 |
Ref: [Construction and identification of recombinant vectors carrying herpes simplex virus thymidine kinase genes expressed in vascular endothelial cells]. PMID: 16480582 Ref: Expression of vascular endothelial growth factor receptors is closely related to the histological grade of hepatocellular carcinoma. PMID: 16786116 Ref: [A relationship between cyclooxygenase-2 expression and tumor angiogenesis in experimental rat liver carcinogenesis]. PMID: 16995982 |
Ref: Increased expression of vascular endothelial growth factor in small hepatocellular carcinoma. PMID: 17244253 Ref: Vascular damage and anti-angiogenic effects of tumor vessel-targeted adenovirus-mediated herpes simplex virus thymidine kinase gene. PMID: 17663519 Ref: Fludarabine reduces survivability of HepG2 cells through VEGF under hypoxia. PMID: 17961496 |
Ref: Anti-angiogenic gene therapy for hepatocellular carcinoma mediated by microbubble-enhanced ultrasound exposure: an in vivo experimental study. PMID: 18569283 Ref: Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro. PMID: 19020729 |
Ref: Vascular endothelial growth factor receptor 2 expression in non-tumorous cirrhotic liver is higher when hepatoma is beyond Milan criteria. PMID: 19177438 Ref: Differential role of circulating endothelial progenitor cells in cirrhotic patients with or without hepatocellular carcinoma. PMID: 19501032 Ref: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation. PMID: 19633424 Ref: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation. PMID: 28001118 |
Ref: Double suicide genes selectively kill human umbilical vein endothelial cells. PMID: 21333030 Ref: Double suicide genes driven by kinase domain insert containing receptor promoter selectively kill human lung cancer cells. PMID: 21418659 Ref: hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers. PMID: 21853101 |
Ref: Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma. PMID: 22120522 Ref: Soluble vascular endothelial growth factor decoy receptor FP3 exerts potent antiangiogenic effects. PMID: 22273580 Ref: Ad-KDRscFv:sTRAIL displays a synergistic antitumor effect without obvious cytotoxicity to normal tissues. PMID: 22406047 Ref: Quantification in molecular ultrasound imaging: a comparative study in mice between healthy liver and a human hepatocellular carcinoma xenograft. PMID: 23197543 Ref: Discovery of potent, orally active compounds of tyrosine kinase and serine/threonine-protein kinase inhibitor with anti-tumor activity in preclinical assays. PMID: 23983378 |
Ref: Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways. PMID: 23755206 |
Ref: Genetic polymorphisms of proangiogenic factors seem to favor hepatocellular carcinoma development in alcoholic cirrhosis. PMID: 24445728 Ref: Des-gamma-carboxy prothrombin (DCP) as a potential autologous growth factor for the development of hepatocellular carcinoma. PMID: 25200250 Ref: Fructopyrano-(1-->4)-glucopyranose inhibits the proliferation of liver cancer cells and angiogenesis in a VEGF/VEGFR dependent manner. PMID: 25550894 |
Ref: Molecularly Targeted Therapy of Human Hepatocellular Carcinoma Xenografts with Radio-iodinated Anti-VEGFR2 Murine-Human Chimeric Fab. PMID: 26021484 Ref: Proangiogenic factors in the development of HCC in alcoholic cirrhosis. PMID: 26193870 Ref: The pan-deacetylase inhibitor panobinostat affects angiogenesis in hepatocellular carcinoma models via modulation of CTGF expression. PMID: 26202945 Ref: [Influence of Tumor Microenvironment of Hepatocellular Carcinoma on the Proliferation of Vascular Endothelial Cells and Vascular Angiogenesis Ability]. PMID: 26485987 |
Ref: Ramucirumab Clinical Development: an Emerging Role in Gastrointestinal Tumors. PMID: 26887374 Ref: A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis. PMID: 27221035 Ref: TTF1, in the Form of Nanoparticles, Inhibits Angiogenesis, Cell Migration and Cell Invasion In Vitro and In Vivo in Human Hepatoma through STAT3 Regulation. PMID: 27834930 |
Ref: Contrary influence of clinically applied sorafenib concentrations among hepatocellular carcinoma patients. PMID: 27936391 Ref: Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells. PMID: 28122355 Ref: RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma. PMID: 28460436 Ref: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors. PMID: 28594907 Ref: Efficacy of Ciji Hua'ai Baosheng formula on the expressions of vascular endothelial growth factor, kinase insert domain-containing receptor and basic fibroblast growth factor in mouse models of H(22) hepatocellular carcinoma. PMID: 29957915 |
Ref: Characterizing key nucleotide polymorphisms of hepatitis C virus-disease associations via mass-spectrometric genotyping. PMID: 29207078 Ref: Apatinib: A Review in Advanced Gastric Cancer and Other Advanced Cancers. PMID: 29663291 Ref: Apatinib as targeted therapy for sarcoma. PMID: 29849960 Ref: Anti-PD-1 Antibody SHR-1210 combined with Apatinib for Advanced Hepatocellular Carcinoma, Gastric or Esophagogastric Junction Cancer: An Open-label, Dose Escalation and Expansion Study. PMID: 30348638 |