Primary Site >> Esophagus Cancer

Gene >> KDR

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Ref: Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) in esophageal squamous cell carcinoma.
PMID: 12553021
Ref: Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis.
PMID: 17200341
Ref: Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation via beta-adrenoceptor-dependent transactivation of extracellular signal-regulated kinase/cyclooxygenase-2 pathway.
PMID: 18452159
Ref: Co-expression of receptor tyrosine kinases in esophageal adenocarcinoma and squamous cell cancer.
PMID: 18813825
Ref: Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways.
PMID: 20039326
Ref: VEGF-C promotes the development of esophageal cancer via regulating CNTN-1 expression.
PMID: 21482472
Ref: Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
PMID: 24708624
Ref: New directions in perioperative management of locally advanced esophagogastric cancer.
PMID: 24857100
Ref: Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy.
PMID: 25595897
Ref: Characterization of the expression and clinical features of epidermal growth factor receptor and vascular endothelial growth factor receptor-2 in esophageal carcinoma.
PMID: 26788193
Ref: Gastric Carcinoma at the Era of Targeted Therapies.
PMID: 25944013
Ref: Targeted therapy in esophageal cancer.
PMID: 26895097
Ref: New Strategies in Esophageal Carcinoma: Translational Insights from Signaling Pathways and Immune Checkpoints.
PMID: 27370606
Ref: Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers.
PMID: 28078044
Ref: Induction Therapy for Locally Advanced, Resectable Esophagogastric Cancer: A Phase I Trial of Vandetanib (ZD6474), Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiotherapy Followed by Resection.
PMID: 26986978
Ref: Contrast-enhanced computed tomography combined with Chitosan-Fe3O4 nanoparticles targeting fibroblast growth factor receptor and vascular endothelial growth factor receptor in the screening of early esophageal cancer.
PMID: 29805549
Ref: Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival.
PMID: 30086460
Ref: MiR-139-5p regulates VEGFR and downstream signaling pathways to inhibit the development of esophageal cancer.
PMID: 30245290