Primary Site >> Liver Cancer
Gene >> KDM5B
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Ref: Fumonisin B1 induces global DNA hypomethylation in HepG2 cells - An alternative mechanism of action. PMID: 24280379 |
Ref: KDM5B is overexpressed in gastric cancer and is required for gastric cancer cell proliferation and metastasis. PMID: 25628922 |
Ref: Depletion of histone demethylase KDM5B inhibits cell proliferation of hepatocellular carcinoma by regulation of cell cycle checkpoint proteins p15 and p27. PMID: 26911146 Ref: Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. PMID: 27224921 |
Ref: Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B. PMID: 28566884 |
Ref: Basil polysaccharide attenuates hepatocellular carcinoma metastasis in rat by suppressing H3K9me2 histone methylation under hepatic artery ligation-induced hypoxia. PMID: 29042275 Ref: Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma. PMID: 30344945 Ref: Increased Expression of Lysine-Specific Demethylase 5B (KDM5B) Promotes Tumor Cell Growth in Hep3B Cells and is an Independent Prognostic Factor in Patients with Hepatocellular Carcinoma. PMID: 30353907 |