Primary Site >> Colorectal Cancer
Gene >> KDM4B
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Ref: Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment. PMID: 17982676 |
Ref: Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth. PMID: 19858293 |
Ref: HIF-1alpha-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism. PMID: 22745382 |
Ref: An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer. PMID: 22345654 |
Ref: Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer. PMID: 24473398 Ref: Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase. PMID: 24481461 Ref: Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. PMID: 24936217 Ref: Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer. PMID: 24957706 |
Ref: KDM4B plays an important role in mitochondrial apoptosis by upregulating HAX1 expression in colorectal cancer. PMID: 27506941 |
Ref: KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage. PMID: 28073943 |
Ref: Role of JMJD2B in colon cancer cell survival under glucose-deprived conditions and the underlying mechanisms. PMID: 28945223 Ref: KDM4B promotes DNA damage response via STAT3 signaling and is a target of CREB in colorectal cancer cells. PMID: 29633065 |