Primary Site >> Colorectal Cancer

Gene >> KCNN4

  • 2009
  • 2010
  • 2013
  • 2014
  • 2016
  • 2018
Ref: Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells.
PMID: 19406468
Ref: An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1.
PMID: 20036632
Ref: KCNN4 channels participate in the EMT induced by PRL-3 in colorectal cancer.
PMID: 23572150
Ref: Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner.
PMID: 24885636
Ref: hERG1 positivity and Glut-1 negativity identifies high-risk TNM stage I and II colorectal cancer patients, regardless of adjuvant chemotherapy.
PMID: 27789963
Ref: The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.
PMID: 29161243