Primary Site >> Colorectal Cancer
Gene >> KAT2B
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Ref: Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y. PMID: 9632821 |
Ref: Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity. PMID: 16227401 Ref: Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma. PMID: 16309230 |
Ref: PCAF acetylates {beta}-catenin and improves its stability. PMID: 18987336 |
Ref: Acetylation of the proto-oncogene EVI1 abrogates Bcl-xL promoter binding and induces apoptosis. PMID: 21980434 |
Ref: Inhibition of PCAF histone acetyltransferase, cytotoxicity and cell permeability of 2-acylamino-1-(3- or 4-carboxy-phenyl)benzamides. PMID: 23128090 |
Ref: Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression. PMID: 23175172 Ref: Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature. PMID: 24052018 |
Ref: Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: enzyme and cellular studies. PMID: 24835815 Ref: Colorectal Cancer-Associated Fibroblasts are Genotypically Distinct. PMID: 25530743 |
Ref: IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction. PMID: 24632618 |
Ref: Dynamic Histone Acetylation of H3K4me3 Nucleosome Regulates MCL1 Pre-mRNA Splicing. PMID: 26864447 Ref: Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment. PMID: 27391808 Ref: Combination of the histone deacetylase inhibitor depsipeptide and 5-fluorouracil upregulates major histocompatibility complex class II and p21 genes and activates caspase-3/7 in human colon cancer HCT-116 cells. PMID: 27509880 Ref: miR-31 affects colorectal cancer cells by inhibiting autophagy in cancer-associated fibroblasts. PMID: 27793031 |
Ref: p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes. PMID: 28158851 Ref: Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration. PMID: 28418886 Ref: The aspirin metabolite salicylate inhibits lysine acetyltransferases and MUC1 induced epithelial to mesenchymal transition. PMID: 28717171 Ref: Prediction of pathological response to neoadjuvant treatment in rectal cancer with a two-protein immunohistochemical score derived from stromal gene-profiling. PMID: 28911071 Ref: Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets. PMID: 29245949 Ref: Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway. PMID: 29254217 |
Ref: Cancer-associated fibroblasts enhance tumor (18)F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT. PMID: 29507627 Ref: Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs. PMID: 29924908 Ref: Analysis of the expression of cancer-associated fibroblast- and EMT-related proteins in submucosal invasive colorectal cancer. PMID: 30087711 |