Primary Site >> Colorectal Cancer
Gene >> JUN
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Ref: A serine protease-inhibitory benzamidine derivative inhibits the growth of human colon carcinoma cells. PMID: 1517149 |
Ref: Immunohistochemical detection of RAS, JUN, FOS, and p53 oncoprotein expression in human colorectal adenomas and carcinomas. PMID: 8264230 Ref: Ubiquitin-ribosomal protein S27a gene overexpressed in human colorectal carcinoma is an early growth response gene. PMID: 8385574 |
Ref: Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. PMID: 8065332 |
Ref: Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin. PMID: 7579691 Ref: Expression of proliferation-specific genes in the mucosa adjacent to colon carcinoma. PMID: 7736875 Ref: Turnover of glutathione S-transferase alpha mRNAs is accelerated by 12-O-tetradecanoyl phorbol-13-acetate in human hepatoma and colon carcinoma cell lines. PMID: 7744032 Ref: Influence of retrovirally transduced human tumor-necrosis-factor-alpha on the expression of C-myc, k-ras, C-jun, p53, tgf-alpha, and cea in human colon-carcinoma cell-lines. PMID: 21556635 |
Ref: Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. PMID: 8631127 Ref: Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease. PMID: 8674385 Ref: Association of resistance-related protein expression with poor vascularization and low levels of oxygen in human rectal cancer. PMID: 8690519 Ref: Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene. PMID: 8798512 Ref: Modulation of colon tumor oncogene expression by cancer patient-derived lipids. PMID: 8841466 Ref: Effect of cytochrome P450 inducers on expression of oncogenes and a tumor suppressor gene in human colon cancer cells. PMID: 21541530 |
Ref: [The diagnosis and surgical treatment in rectal endometriosis]. PMID: 10374526 Ref: Suppression of serum-induced c-jun expression by activated Ki-ras in human colon cancer cells. PMID: 12503187 |
Ref: Momordins inhibit both AP-1 function and cell proliferation. PMID: 9568065 Ref: Inhibition of fos-jun-DNA complex formation by dihydroguaiaretic acid and in vitro cytotoxic effects on cancer cells. PMID: 9619854 Ref: Butyrate inhibits colon carcinoma cell growth through two distinct pathways. PMID: 9706145 |
Ref: Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras. PMID: 9926923 Ref: Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells. PMID: 10344756 Ref: A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor. PMID: 10447677 Ref: Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis. PMID: 10471035 Ref: 1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiation. PMID: 10585423 |
Ref: Differentially expressed genes in asbestos-induced tumorigenic human bronchial epithelial cells: implication for mechanism. PMID: 11062161 Ref: Recent studies on the biofunctions and biotransformations of curcumin. PMID: 11237176 |
Ref: The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. PMID: 11158322 Ref: Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells. PMID: 11208715 Ref: Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1. PMID: 11278263 Ref: A possible role for the WNT-1 pathway in oral carcinogenesis. PMID: 11345525 Ref: Mechanisms of cancer chemoprevention by curcumin. PMID: 11370761 Ref: Alterations of MAPK activities associated with intestinal cell differentiation. PMID: 11394874 Ref: Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells. PMID: 11506814 Ref: Colorectal cancers--experience at a regional cancer centre in India. PMID: 11552491 |
Ref: Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. PMID: 11950812 Ref: Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis. PMID: 12069855 Ref: Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. PMID: 12221076 Ref: Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). PMID: 12351151 |
Ref: Platelet-activating factor activates mitogen-activated protein kinases, inhibits proliferation, induces differentiation and suppresses the malignant phenotype of human colon carcinoma cells. PMID: 12687020 Ref: Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells. PMID: 12707033 Ref: Differential gene expression profiles and identification of the genes relevant to clinicopathologic factors in colorectal cancer selected by cDNA array method in combination with principal component analysis. PMID: 12792775 Ref: Transcriptional regulation of cyclo-oxygenase expression: three pillars of control. PMID: 14552705 Ref: The chemopreventive bioflavonoid apigenin modulates signal transduction pathways in keratinocyte and colon carcinoma cell lines. PMID: 14608117 Ref: Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells. PMID: 14625389 Ref: Genetic signatures of differentiation induced by 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells. PMID: 14633706 |
Ref: Dominant-negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer. PMID: 14712303 Ref: Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells. PMID: 14767471 Ref: p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. PMID: 15037631 Ref: Targets of 17beta-oestradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? PMID: 15128281 Ref: Modulation of AP-1 by natural chemopreventive compounds in human colon HT-29 cancer cell line. PMID: 15139522 Ref: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells. PMID: 15256484 Ref: Transcriptional responses to epigallocatechin-3 gallate in HT 29 colon carcinoma spheroids. PMID: 15265009 Ref: Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-g PMID: 15289320 Ref: Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells. PMID: 15298620 Ref: The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells. PMID: 15504750 |
Ref: Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells. PMID: 15713899 Ref: Bile acids induce MUC2 overexpression in human colon carcinoma cells. PMID: 15754327 Ref: Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis. PMID: 15790589 Ref: Modulation of CDK2-AP1 (p12(DOC-1)) expression in human colorectal cancer. PMID: 15806176 Ref: (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells. PMID: 15860507 Ref: Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis. PMID: 15922743 Ref: Differential expression of the AP-1 transcription factor family members in human colorectal epithelial and neuroendocrine neoplasms. PMID: 15923159 Ref: Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells. PMID: 15930183 Ref: Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression. PMID: 15935729 Ref: Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells. PMID: 15951156 Ref: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway. PMID: 15956247 Ref: The novel gene EG-1 stimulates cellular proliferation. PMID: 16024617 Ref: Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity. PMID: 16033843 Ref: Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species. PMID: 16118226 Ref: Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. PMID: 16170031 Ref: Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation. PMID: 16285957 Ref: CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability. PMID: 16357143 Ref: Combination analysis of activator protein-1 family members, Sp1 and an activator protein-2alpha-related factor binding to different regions of the urokinase receptor gene in resected colorectal cancers. PMID: 16361535 |
Ref: Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1. PMID: 16343055 Ref: T cell deficiency leads to liver carcinogenesis in azoxymethane-treated rats. PMID: 16380649 Ref: TAK1-mediated stress signaling pathways are essential for TNF-alpha-promoted pulmonary metastasis of murine colon cancer cells. PMID: 16385569 Ref: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. PMID: 16401477 Ref: Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. PMID: 16449643 Ref: Arachidonic acid-induced gene expression in colon cancer cells. PMID: 16704987 Ref: Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis. PMID: 16715131 Ref: Aspirin upregulates expression of urokinase type plasminogen activator receptor (uPAR) gene in human colon cancer cells through AP1. PMID: 16893520 |
Ref: The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt. PMID: 16912864 Ref: Growth suppression of human cancer cells by polyphenolics from sweetpotato (Ipomoea batatas L.) leaves. PMID: 17199331 Ref: Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. PMID: 17383428 Ref: Expression of EIF3-p48/INT6, TID1 and Patched in cancer, a profiling of multiple tumor types and correlation of expression. PMID: 17385060 Ref: Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer. PMID: 17510314 Ref: Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells. PMID: 17510397 Ref: 2-hydroxycinnamaldehyde inhibits SW620 colon cancer cell growth through AP-1 inactivation. PMID: 17510524 Ref: Synergistic effects of RXR alpha and PPAR gamma ligands to inhibit growth in human colon cancer cells--phosphorylated RXR alpha is a critical target for colon cancer management. PMID: 17604322 Ref: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. PMID: 17673978 Ref: Involvement of RNA helicases p68 and p72 in colon cancer. PMID: 17699760 Ref: Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice. PMID: 17868752 Ref: EGF-R is expressed and AP-1 and NF-kappaB are activated in stromal myofibroblasts surrounding colon adenocarcinomas paralleling expression of COX-2 and VEGF. PMID: 18032824 |
Ref: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB. PMID: 18241858 Ref: Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin. PMID: 18436711 Ref: Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress. PMID: 18534616 Ref: Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling. PMID: 18593907 Ref: Moscatilin induces apoptosis in human colorectal cancer cells: a crucial role of c-Jun NH2-terminal protein kinase activation caused by tubulin depolymerization and DNA damage. PMID: 18594007 Ref: Evaluation of the potential anti-cancer activity of the antidepressant sertraline in human colon cancer cell lines and in colorectal cancer-xenografted mice. PMID: 18636148 Ref: The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice. PMID: 18679426 Ref: A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. PMID: 18852287 Ref: Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. PMID: 18929641 Ref: Rosmarinic acid antagonizes activator protein-1-dependent activation of cyclooxygenase-2 expression in human cancer and nonmalignant cell lines. PMID: 18936204 Ref: Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors. PMID: 18992165 |
Ref: High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma. PMID: 18825388 Ref: NDRG2 suppresses cell proliferation through down-regulation of AP-1 activity in human colon carcinoma cells. PMID: 18844221 Ref: N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1. PMID: 19058178 Ref: Loss of E-cadherin-mediated cell-cell contacts activates a novel mechanism for up-regulation of the proto-oncogene c-Jun. PMID: 19193763 Ref: Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts. PMID: 19232820 Ref: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines. PMID: 19352384 Ref: Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors. PMID: 19420964 Ref: NGX6 inhibits AP-1 and Ets-1 expression and down-regulates cyclin D1 in human colorectal cancer. PMID: 19499154 Ref: Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells. PMID: 19773752 Ref: The NF-kappaB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1beta. PMID: 19779850 Ref: Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo. PMID: 19885606 |
Ref: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. PMID: 20136087 Ref: Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway. PMID: 20198339 Ref: p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9. PMID: 20231272 Ref: Extracellular signal-regulated kinase 8-mediated c-Jun phosphorylation increases tumorigenesis of human colon cancer. PMID: 20395206 Ref: Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. PMID: 20460455 Ref: Effect of soy saponin on the growth of human colon cancer cells. PMID: 20632438 Ref: F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor. PMID: 20638938 Ref: Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1. PMID: 20653974 |
Ref: Regulation of Nur77 expression by beta-catenin and its mitogenic effect in colon cancer cells. PMID: 20847229 Ref: Diversity of axin in signaling pathways and its relation to colorectal cancer. PMID: 21053101 Ref: c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex. PMID: 21196933 Ref: FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation. PMID: 21282377 Ref: COX-2 contributes to P-glycoprotein-mediated multidrug resistance via phosphorylation of c-Jun at Ser63/73 in colorectal cancer. PMID: 21296766 Ref: SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. PMID: 21368833 Ref: Functional variants of -1318T > G and -673C > T in c-Jun promoter region associated with increased colorectal cancer risk by elevating promoter activity. PMID: 21393476 Ref: Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells. PMID: 21406062 Ref: STAT3 controls matrix metalloproteinase-1 expression in colon carcinoma cells by both direct and AP-1-mediated interaction with the MMP-1 promoter. PMID: 21410405 Ref: Expression of KITENIN in human colorectal cancer and its relation to tumor behavior and progression. PMID: 21418393 Ref: A paraptosis-like cell death induced by delta-tocotrienol in human colon carcinoma SW620 cells is associated with the suppression of the Wnt signaling pathway. PMID: 21453743 Ref: [Role of NGX6 in Wnt/beta-catenin signaling pathway in colon cancer]. PMID: 21464545 Ref: Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells. PMID: 21467134 Ref: ALDOSE REDUCTASE: New Insights for an Old Enzyme. PMID: 21547010 Ref: Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation. PMID: 21653830 Ref: Enormous influence of TNIK knockdown on intracellular signals and cell survival. PMID: 21710359 Ref: Dimerumic acid inhibits SW620 cell invasion by attenuating H(2)O(2)-mediated MMP-7 expression via JNK/C-Jun and ERK/C-Fos activation in an AP-1-dependent manner. PMID: 21814482 Ref: Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. PMID: 22025878 |
Ref: PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation. PMID: 22252525 Ref: Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro. PMID: 22438101 Ref: Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice. PMID: 22461519 Ref: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging. PMID: 22465936 Ref: Association of c-Jun gene polymorphism with susceptibility to systemic lupus erythematosus in a Chinese population. PMID: 22489574 Ref: Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms. PMID: 22851508 Ref: Transcriptional regulation of PES1 expression by c-Jun in colon cancer. PMID: 22860098 Ref: Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer. PMID: 22870247 Ref: Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis. PMID: 22893789 Ref: MAP kinase genes and colon and rectal cancer. PMID: 23027623 Ref: PAX2 protein induces expression of cyclin D1 through activating AP-1 protein and promotes proliferation of colon cancer cells. PMID: 23135283 Ref: [Experimental study on delta-tocotrienol inhibits the Wnt pathway in the colon cancer cell SW620]. PMID: 23424864 |
Ref: Possible involvement of Wnt11 in colorectal cancer progression. PMID: 22161723 Ref: Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a. PMID: 22978663 Ref: EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells. PMID: 23116973 Ref: microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis. PMID: 23208495 Ref: 6 Iodo-delta-lactone: a derivative of arachidonic acid with antitumor effects in HT-29 colon cancer cells. PMID: 23375358 Ref: Crosstalk between Wnt Signaling and RNA Processing in Colorectal Cancer. PMID: 23386908 Ref: Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: hirsutanol A inhibits tumor growth through ROS production. PMID: 23394457 Ref: gamma-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. PMID: 23469066 Ref: CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a. PMID: 23533633 Ref: Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer. PMID: 23588207 Ref: TF/FVIIa/PAR2 promotes cell proliferation and migration via PKCalpha and ERK-dependent c-Jun/AP-1 pathway in colon cancer cell line SW620. PMID: 23616010 Ref: Cholesterol affects gene expression of the Jun family in colon carcinoma cells using different signaling pathways. PMID: 23643895 Ref: S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer. PMID: 23693020 Ref: Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer. PMID: 23800415 Ref: Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells. PMID: 23859040 Ref: Asymmetric dimethylarginine attenuates serum starvation-induced apoptosis via suppression of the Fas (APO-1/CD95)/JNK (SAPK) pathway. PMID: 24091673 Ref: AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas. PMID: 24396595 |
Ref: Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines. PMID: 23676439 Ref: Licochalcone A, a natural inhibitor of c-Jun N-terminal kinase 1. PMID: 24253317 Ref: Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase. PMID: 24481461 Ref: JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy. PMID: 24733045 Ref: Elf3 drives beta-catenin transactivation and associates with poor prognosis in colorectal cancer. PMID: 24874735 Ref: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells. PMID: 24893630 Ref: The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer. PMID: 24960159 Ref: Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite. PMID: 24983769 Ref: Involvement of the CREB5 regulatory network in colorectal cancer metastasis. PMID: 25076032 Ref: miR200c attenuates P-gp-mediated MDR and metastasis by targeting JNK2/c-Jun signaling pathway in colorectal cancer. PMID: 25205654 Ref: Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers. PMID: 25260534 |
Ref: Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma. PMID: 25335113 Ref: Twist1 and AP-1 cooperatively upregulate integrin alpha5 expression to induce invasion and the epithelial-mesenchymal transition. PMID: 25600770 Ref: MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway. PMID: 25602366 Ref: The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma. PMID: 25728681 Ref: NPC1L1 knockout protects against colitis-associated tumorigenesis in mice. PMID: 25881076 Ref: DNA methylation levels and long-term trihalomethane exposure in drinking water: an epigenome-wide association study. PMID: 26039576 Ref: Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels. PMID: 26091349 Ref: HIF1alpha deficiency reduces inflammation in a mouse model of proximal colon cancer. PMID: 26183215 Ref: An Integrative Approach for Mapping Differentially Expressed Genes and Network Components Using Novel Parameters to Elucidate Key Regulatory Genes in Colorectal Cancer. PMID: 26222778 Ref: Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells. PMID: 26318418 Ref: Protein-Protein Interaction Network could reveal the relationship between the breast and colon cancer. PMID: 26328044 Ref: Molecular mechanism of anticancer effect of Sclerotium rolfsii lectin in HT29 cells involves differential expression of genes associated with multiple signaling pathways: A microarray analysis. PMID: 26347523 Ref: Antiproliferative and Apoptotic Activity of Chamaecyparis obtusa Leaf Extract against the HCT116 Human Colorectal Cancer Cell Line and Investigation of the Bioactive Compound by Gas Chromatography-Mass Spectrometry-Based Metabolomics. PMID: 26445036 Ref: JNK signaling pathway is involved in piperlongumine-mediated apoptosis in human colorectal cancer HCT116 cells. PMID: 26622558 Ref: Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice. PMID: 26693068 |
Ref: DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53. PMID: 26494468 Ref: Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss. PMID: 26527747 Ref: TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway. PMID: 26701208 Ref: Magnetically triggered nanovehicles for controlled drug release as a colorectal cancer therapy. PMID: 26705859 Ref: Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis. PMID: 26755651 Ref: Histone deacetylase 2 regulates doxorubicin (Dox) sensitivity of colorectal cancer cells by targeting ABCB1 transcription. PMID: 26846508 Ref: Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways. PMID: 26918455 Ref: In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells. PMID: 27043582 Ref: Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. PMID: 27065323 Ref: c-Jun NH2-teminal kinase 1 interacts with vitamin D receptor and affects vitamin D-mediated inhibition of cancer cell proliferation. PMID: 27174721 Ref: [Propensity score matching-based analysis of short-term outcomes of Laparoscopic-assisted Natural Orifice Specimen Extraction for left colorectal cancer radical resection]. PMID: 27266686 Ref: The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway. PMID: 27338550 Ref: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1. PMID: 27529686 |
Ref: KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation. PMID: 27648936 Ref: p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription. PMID: 27926494 Ref: Integrative genomic approaches to dissect clinically-significant relationships between the VDR cistrome and gene expression in primary colon cancer. PMID: 28027912 Ref: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45. PMID: 28068431 Ref: WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice. PMID: 28222755 Ref: IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment. PMID: 28249897 Ref: Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. PMID: 28255344 Ref: The genetic basis of obesity complications. PMID: 28362475 Ref: SCF/C-Kit/JNK/AP-1 Signaling Pathway Promotes Claudin-3 Expression in Colonic Epithelium and Colorectal Carcinoma. PMID: 28383479 Ref: Inactivation of JNK2 as carcinogenic factor in colitis-associated and sporadic colorectal carcinogenesis. PMID: 28383667 Ref: RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer. PMID: 28445956 Ref: ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types. PMID: 28611196 Ref: omega-3 Polyunsaturated fatty acids and their cytochrome P450-derived metabolites suppress colorectal tumor development in mice. PMID: 28672272 Ref: Identification of the anticancer effects of a novel proteasome inhibitor, ixazomib, on colorectal cancer using a combined method of microarray and bioinformatics analysis. PMID: 28790851 Ref: RASSF6 downregulation promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal cancer. PMID: 28903410 Ref: c-Jun-mediated beta-1,3-N-acetylglucosaminyltransferase 8 expression: A novel mechanism regulating the invasion and metastasis of colorectal carcinoma cells. PMID: 28927138 Ref: Identification of hypoxia-regulated angiogenic genes in colorectal cancer. PMID: 28928094 Ref: JAB1-STAT3 activation loop is associated with recurrence following 5-fluorouracil-based adjuvant chemotherapy in human colorectal cancer. PMID: 29113268 Ref: The Herb-Drug Pharmacokinetic Interaction of 5-Fluorouracil and Its Metabolite 5-Fluoro-5,6-Dihydrouracil with a Traditional Chinese Medicine in Rats. PMID: 29295501 |
Ref: p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells. PMID: 29402939 Ref: Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11-mediated non-canonical Wnt signaling. PMID: 29427622 Ref: Identification of genomic expression differences between right-sided and left-sided colon cancer based on bioinformatics analysis. PMID: 29430186 Ref: Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model. PMID: 29432917 Ref: MicroRNA hsa-let-7e-5p as a potential prognosis marker for rectal carcinoma with liver metastases. PMID: 29731866 Ref: Puerarin 6''-O-xyloside possesses significant antitumor activities on colon cancer through inducing apoptosis. PMID: 30344709 |