Primary Site >> Colorectal Cancer

Gene >> JRK

  • 2011
  • 2016
  • 2017
Ref: Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating beta-catenin-TCF activity.
PMID: 21399610
 Ref: JRK is a positive regulator of beta-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.
PMID: 26455321
 Ref: Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.
PMID: 28708826