Primary Site >> Stomach Cancer
Gene >> JAK2
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Ref: Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells. PMID: 16230373 |
Ref: Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers. PMID: 18559588 |
Ref: Anti-inflammatory actions of probiotics through activating suppressor of cytokine signaling (SOCS) expression and signaling in Helicobacter pylori infection: a novel mechanism. PMID: 20136974 Ref: The development of gastric cancer in a patient with polycythemia Vera, 3P deletion, and JAK2 V617F mutation. PMID: 20306156 Ref: KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach. PMID: 20358631 Ref: MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. PMID: 20548334 Ref: [Helicobacter pylori cytotoxin associated protein CagA regulates gastrin gene promoter activity]. PMID: 21029692 |
Ref: Human gastrin mRNA expression up-regulated by Helicobacter pylori CagA through MEK/ERK and JAK2-signaling pathways in gastric cancer cells. PMID: 21509655 Ref: Targeting miR-375 in gastric cancer. PMID: 21557705 Ref: The effects of recombinant human GH on promoting tumor growth depend on the expression of GH receptor in vivo. PMID: 21920991 |
Ref: Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. PMID: 22203730 Ref: MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. PMID: 22310976 |
Ref: STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells. PMID: 23333463 Ref: Gastrin acting on the cholecystokinin2 receptor induces cyclooxygenase-2 expression through JAK2/STAT3/PI3K/Akt pathway in human gastric cancer cells. PMID: 23376640 Ref: OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells. PMID: 23402820 Ref: Overexpression of AKT decreases the chemosensitivity of gastric cancer cells to cisplatin in vitro and in vivo. PMID: 23546174 Ref: Janus kinase 2 polymorphisms are associated with risk in patients with gastric cancer in a Chinese population. PMID: 23717640 Ref: [Effect of rhGH on JAK2-STAT3 signal pathway after GHR was down-regulated by siRNA in gastric cancer cell]. PMID: 23724661 Ref: Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine. PMID: 24063987 Ref: Involvement of nuclear JAK2 signaling in AG490-induced apoptosis of gastric cancer cells. PMID: 24151255 |
Ref: ERK1/2 inhibition enhances apoptosis induced by JAK2 silencing in human gastric cancer SGC7901 cells. PMID: 24178240 Ref: miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling. PMID: 24718681 Ref: Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo. PMID: 24804649 Ref: Snail-regulated MiR-375 inhibits migration and invasion of gastric cancer cells by targeting JAK2. PMID: 25055044 Ref: Comprehensive molecular characterization of gastric adenocarcinoma. PMID: 25079317 |
Ref: A MDM2-dependent positive-feedback loop is involved in inhibition of miR-375 and miR-106b induced by Helicobacter pylori lipopolysaccharide. PMID: 25307786 Ref: Ponicidin induces apoptosis via JAK2 and STAT3 signaling pathways in gastric carcinoma. PMID: 25588213 Ref: Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma. PMID: 25613731 Ref: Update on Epstein-Barr virus and gastric cancer (review). PMID: 25633561 Ref: CXCL1 promotes tumor growth through VEGF pathway activation and is associated with inferior survival in gastric cancer. PMID: 25641338 Ref: Myeloid cell leukemia-1 regulates the cell growth and predicts prognosis in gastric cancer. PMID: 25672320 Ref: Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells. PMID: 25815436 Ref: Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing. PMID: 26251698 Ref: Feed-Forward Reciprocal Activation of PAFR and STAT3 Regulates Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer. PMID: 26359459 Ref: [Analysis of gastric cancer tissues genome methylation by DNA methylation chip]. PMID: 26499154 |
Ref: Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer cells. PMID: 26508024 Ref: Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus-associated gastric carcinoma. PMID: 26980034 Ref: Piperlongumine inhibits gastric cancer cells via suppression of the JAK1,2/STAT3 signaling pathway. PMID: 27053336 Ref: Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis. PMID: 27109105 Ref: Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway. PMID: 27121055 Ref: Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro. PMID: 27122665 Ref: Recent updates of precision therapy for gastric cancer: Towards optimal tailored management. PMID: 27217696 Ref: [New molecular classification of colorectal cancer, pancreatic cancer and stomach cancer: Towards "a la carte" treatment?]. PMID: 27345450 Ref: Type II cGMPdependent protein kinase inhibits EGFinduced JAK/STAT signaling in gastric cancer cells. PMID: 27357186 Ref: Anticancer effect of cucurbitacin B on MKN-45 cells via inhibition of the JAK2/STAT3 signaling pathway. PMID: 27698776 |
Ref: Epstein-Barr Virus-associated Gastric Cancer and Potential Mechanisms of Oncogenesis. PMID: 27677953 Ref: Gastric Cancer Cell Proliferation and Survival Is Enabled by a Cyclophilin B/STAT3/miR-520d-5p Signaling Feedback Loop. PMID: 28011625 Ref: IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway. PMID: 28186964 Ref: Basic Transcription Factor 3 Is Required for Proliferation and Epithelial-Mesenchymal Transition via Regulation of FOXM1 and JAK2/STAT3 Signaling in Gastric Cancer. PMID: 28276310 Ref: GKN2 increases apoptosis, reduces the proliferation and invasion ability of gastric cancer cells through down-regulating the JAK/STAT signaling pathway. PMID: 28337309 Ref: REG3A promotes the proliferation, migration, and invasion of gastric cancer cells. PMID: 28435292 Ref: Knockdown of long non-coding RNA HOXD-AS1 inhibits gastric cancer cell growth via inactivating the JAK2/STAT3 pathway. PMID: 28475004 Ref: C-X-C motif chemokine receptor 4 promotes tumor angiogenesis in gastric cancer via activation of JAK2/STAT3. PMID: 28544312 Ref: SIRT6 inhibits growth of gastric cancer by inhibiting JAK2/STAT3 pathway. PMID: 28656307 Ref: Downregulation of Piwil3 suppresses cell proliferation, migration and invasion in gastric cancer. PMID: 28869440 Ref: B7-H3 promotes gastric cancer cell migration and invasion. PMID: 29069741 Ref: The conundrum of the Epstein-Barr virus-associated gastric carcinoma in the Americas. PMID: 29088902 Ref: RNAi-mediated silencing of NOX4 inhibited the invasion of gastric cancer cells through JAK2/STAT3 signaling. PMID: 29118906 Ref: MicroRNA-216a inhibits the metastasis of gastric cancer cells by targeting JAK2/STAT3-mediated EMT process. PMID: 29179483 Ref: IFNgamma induces PD-L1 overexpression by JAK2/STAT1/IRF-1 signaling in EBV-positive gastric carcinoma. PMID: 29259270 |
Ref: Effects of purified Omphalia lapidescens protein on metastasis, cell cycle, apoptosis and the JAK-STAT signaling pathway in SGC-7901 human gastric cells. PMID: 29102525 Ref: Apigetrin inhibits gastric cancer progression through inducing apoptosis and regulating ROS-modulated STAT3/JAK2 pathway. PMID: 29408335 Ref: Effects of purified Omphalia lapidescens protein on metastasis, cell cycle, apoptosis and the JAK-STAT signaling pathway in SGC-7901 human gastric cells. PMID: 29541181 Ref: Highly Expressed Granulocyte Colony-Stimulating Factor (G-CSF) and Granulocyte Colony-Stimulating Factor Receptor (G-CSFR) in Human Gastric Cancer Leads to Poor Survival. PMID: 29567938 Ref: Prognostic significance of microsatellite instabilityassociated pathways and genes in gastric cancer. PMID: 29717769 Ref: miR-337-3p suppresses the proliferation and invasion of hepatocellular carcinoma cells through targeting JAK2. PMID: 29736311 Ref: Knockdown of TMEM45B inhibits cell proliferation and invasion in gastric cancer. PMID: 29803169 Ref: Induction of Pro-Inflammatory Response via Activated Macrophage-Mediated NF-kappaB and STAT3 Pathways in Gastric Cancer Cells. PMID: 29929193 Ref: Growth hormone-releasing hormone (GHRH) and its agonists inhibit hepatic and tumoral secretion of IGF-1. PMID: 29983893 Ref: Pachymic acid inhibits growth and induces cell cycle arrest and apoptosis in gastric cancer SGC-7901 cells. PMID: 30013646 Ref: Oxymatrine exhibits anti-tumor activity in gastric cancer through inhibition of IL-21R-mediated JAK2/STAT3 pathway. PMID: 30103640 Ref: Ceramide synthase 6 predicts the prognosis of human gastric cancer: It functions as an oncoprotein by dysregulating the SOCS2/JAK2/STAT3 pathway. PMID: 30129684 Ref: HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis. PMID: 30158543 Ref: EBV-associated gastric cancer evades T-cell immunity by PD-1/PD-L1 interactions. PMID: 30264329 |