Primary Site >> Biliary tract Cancer
Gene >> JAK2
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Ref: Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor. PMID: 27211817 Ref: FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. PMID: 27216177 |
Ref: JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling. PMID: 28337870 Ref: Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkappaB pathways in cholangiocarcinoma cells. PMID: 28670110 |
Ref: Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy. PMID: 30015925 |