Primary Site >> Stomach Cancer

Gene >> JAG1

  • 2006
  • 2007
  • 2011
  • 2016
  • 2017
  • 2018
Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: Notch signaling in gastrointestinal tract (review).
PMID: 17143535
Ref: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer.
PMID: 17273778
Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
PMID: 17273804
Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs.
PMID: 17390031
Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.
PMID: 17568183
Ref: Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.
PMID: 22249198
Ref: miR-124 interacts with the Notch1 signalling pathway and has therapeutic potential against gastric cancer.
PMID: 26612211
Ref: Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1.
PMID: 28260102
Ref: COX-2 regulates Snail expression in gastric cancer via the Notch1 signaling pathway.
PMID: 28586004
Ref: Expression of miR-634 in gastric carcinoma and its effects on proliferation, migration, and invasion of gastric cancer cells.
PMID: 29464926
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
PMID: 29786110
Ref: KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer.
PMID: 29956735
Ref: Tanshinone IIA inhibits cell proliferation and tumor growth by downregulating STAT3 in human gastric cancer.
PMID: 30214513