Primary Site >> Colorectal Cancer
Gene >> JAG1
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Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells. PMID: 16525728 |
Ref: Notch signaling in gastrointestinal tract (review). PMID: 17143535 Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 |
Ref: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism. PMID: 20730438 Ref: [Tea polyphenol inhibits colorectal cancer with microsatellite instability by regulating the expressions of HES1, JAG1, MT2A and MAFA]. PMID: 20836978 |
Ref: [Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1]. PMID: 21866461 |
Ref: Expression and clinical significance of Notch signaling genes in colorectal cancer. PMID: 22219033 Ref: [Expression of JAG1 and DLL1 genes in colorectal cancer and its clinical significance]. PMID: 22539391 |
Ref: Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling. PMID: 23525843 Ref: Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. PMID: 23585443 Ref: Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells. PMID: 23698634 |
Ref: A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer. PMID: 26152787 Ref: High expression of the Notch ligand Jagged-1 is associated with poor prognosis after surgery for colorectal cancer. PMID: 27589478 |
Ref: miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT. PMID: 28161537 Ref: Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells. PMID: 28637464 Ref: Apelin13/APJ promotes proliferation of colon carcinoma by activating Notch3 signaling pathway. PMID: 29254197 |
Ref: Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages. PMID: 29580202 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer. PMID: 29879147 Ref: Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells. PMID: 30065304 |