Primary Site >> Colorectal Cancer
Gene >> ITK
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Ref: Cytotoxicity of mitomycin C on clonogenic human carcinoma cells is not enhanced by hypoxia. PMID: 6423304 |
Ref: The effect of tumor CEA content and tumor size on tissue uptake of indium 111-labeled anti-CEA monoclonal antibody. PMID: 3942992 |
Ref: Blood flow failure as a major determinant in the antitumor action of flavone acetic acid. PMID: 2733044 |
Ref: Serum albumin as a vehicle for zinc phthalocyanine: photodynamic activities in solid tumour models. PMID: 8980386 |
Ref: Water-soluble aluminium phthalocyanine-polymer conjugates for PDT: photodynamic activities and pharmacokinetics in tumour-bearing mice. PMID: 10408394 Ref: Colonic adenomas with extramedullary myeloid tumor (granulocytic sarcoma). PMID: 10492089 Ref: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. PMID: 10521789 Ref: MTA (LY231514) in combination treatment regimens using human tumor xenografts and the EMT-6 murine mammary carcinoma. PMID: 10598556 |
Ref: Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. PMID: 16857785 Ref: Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. PMID: 17086355 |
Ref: The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. PMID: 17486063 |
Ref: The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression. PMID: 18350253 |
Ref: A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis. PMID: 19340593 Ref: Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. PMID: 19417139 Ref: Bestrophin 1 promotes epithelial-to-mesenchymal transition of renal collecting duct cells. PMID: 19470678 Ref: Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. PMID: 19502595 Ref: Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion. PMID: 19639199 Ref: Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers. PMID: 20046424 Ref: Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion. PMID: 20049737 |
Ref: The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression. PMID: 20138990 Ref: Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PMID: 20421926 Ref: [Stem cells and colorectal cancerogenesis: new insight]. PMID: 20548278 Ref: Tumor promoting effects of CD95 signaling in chemoresistant cells. PMID: 20573240 Ref: Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells. PMID: 20811713 Ref: BI 5700, a Selective Chemical Inhibitor of IkappaB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression. PMID: 21779445 |
Ref: Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells. PMID: 21241068 Ref: EMT is the dominant program in human colon cancer. PMID: 21251323 Ref: Creatine kinase brain overexpression protects colorectal cells from various metabolic and non-metabolic stresses. PMID: 21308735 Ref: Slug expression enhances tumor formation in a noninvasive rectal cancer model. PMID: 21470622 Ref: Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin. PMID: 21504235 Ref: LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines. PMID: 21829496 Ref: Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. PMID: 21929751 Ref: Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro. PMID: 22042972 Ref: beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. PMID: 22080605 |
Ref: Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis. PMID: 21874049 Ref: Increase of alpha-SMA(+) and CK (+) cells as an early sign of epithelial-mesenchymal transition during colorectal carcinogenesis. PMID: 21912905 Ref: Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis. PMID: 22452538 Ref: A molecular signature for oncogenic BRAF in human colon cancer cells is revealed by microarray analysis. PMID: 22515520 Ref: Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism. PMID: 22637725 Ref: DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial-mesenchymal transition in human breast cancer. PMID: 22719072 Ref: Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells. PMID: 22719836 Ref: ESM-1 regulates cell growth and metastatic process through activation of NF-kappaB in colorectal cancer. PMID: 22735811 Ref: Roles of miRNA in the initiation and development of colorectal carcinoma. PMID: 23092344 Ref: MED12 controls the response to multiple cancer drugs through regulation of TGF-beta receptor signaling. PMID: 23178117 Ref: Colon cancer at the molecular level--usefulness of epithelial-mesenchymal transition analysis. PMID: 23700897 |
Ref: MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. PMID: 22735571 Ref: Roles of miRNA in the initiation and development of colorectal carcinoma. PMID: 23092337 Ref: APC/beta-catenin-rich complexes at membrane protrusions regulate mammary tumor cell migration and mesenchymal morphology. PMID: 23302090 Ref: SLIT2 inhibits cell migration in colorectal cancer through the AKT-GSK3beta signaling pathway. PMID: 23314850 Ref: Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression. PMID: 23441132 Ref: PDGFRB promotes liver metastasis formation of mesenchymal-like colorectal tumor cells. PMID: 23441134 Ref: Metastasis-associated in colon cancer-1 upregulation predicts a poor prognosis of gastric cancer, and promotes tumor cell proliferation and invasion. PMID: 23457029 Ref: Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models. PMID: 23543898 Ref: Low-concentration capsaicin promotes colorectal cancer metastasis by triggering ROS production and modulating Akt/mTOR and STAT-3 pathways. PMID: 23581408 Ref: Upregulation of microRNA-155 promotes the migration and invasion of colorectal cancer cells through the regulation of claudin-1 expression. PMID: 23588589 Ref: DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer. PMID: 23610444 Ref: p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells. PMID: 23624843 Ref: Presence of Twist1-positive neoplastic cells in the stroma of chromosome-unstable colorectal tumors. PMID: 23684708 Ref: Bone marrow-derived CD11b+Jagged2+ cells promote epithelial-to-mesenchymal transition and metastasization in colorectal cancer. PMID: 23722542 Ref: Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells. PMID: 23726031 Ref: Combined aberrant expression of E-cadherin and S100A4, but not beta-catenin is associated with disease-free survival and overall survival in colorectal cancer patients. PMID: 23783026 Ref: Epithelial-mesenchymal transition and its role in the pathogenesis of colorectal cancer. PMID: 23803016 Ref: Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer. PMID: 23836465 Ref: Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models. PMID: 23873089 Ref: FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. PMID: 23943801 Ref: Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer. PMID: 23970932 Ref: TGF-beta: an emerging player in drug resistance. PMID: 23974105 Ref: Impact of microRNAs on regulatory networks and pathways in human colorectal carcinogenesis and development of metastasis. PMID: 23987127 Ref: High expression level of TMPRSS4 predicts adverse outcomes of colorectal cancer patients. PMID: 24072509 Ref: Epigenetic silencing of CXCL14 induced colorectal cancer migration and invasion. PMID: 24099668 Ref: B cell regulation of anti-tumor immune response. PMID: 24293009 |
Ref: MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN. PMID: 24026406 Ref: Maintenance of the stemness in CD44(+) HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression. PMID: 24145190 Ref: MicroRNA-200b stimulates tumour growth in TGFBR2-null colorectal cancers by negatively regulating p27/kip1. PMID: 24151081 Ref: Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-beta. PMID: 24214914 Ref: Wnt5a suppresses colon cancer by inhibiting cell proliferation and epithelial-mesenchymal transition. PMID: 24464650 Ref: Single nucleotide polymorphisms in the metastasis-associated in colon cancer-1 gene predict the recurrence of hepatocellular carcinoma after transplantation. PMID: 24465159 Ref: Targeting Six1 by lentivirus-mediated RNA interference inhibits colorectal cancer cell growth and invasion. PMID: 24551283 Ref: Angiogenic sprouting is regulated by endothelial cell expression of Slug. PMID: 24554431 Ref: Colorectal cancer progression: lessons from Drosophila? PMID: 24583474 Ref: Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. PMID: 24590808 Ref: miR-30b regulates migration and invasion of human colorectal cancer via SIX1. PMID: 24593661 Ref: IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. PMID: 24642471 Ref: CCL20 and CXCL8 synergize to promote progression and poor survival outcome in patients with colorectal cancer by collaborative induction of the epithelial-mesenchymal transition. PMID: 24657657 Ref: Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. PMID: 24691442 Ref: EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer. PMID: 24704156 Ref: MiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1. PMID: 24705396 Ref: MiR-199a-5p loss up-regulated DDR1 aggravated colorectal cancer by activating epithelial-to-mesenchymal transition related signaling. PMID: 24711074 Ref: Epithelial-to-mesenchymal transition and the cancer stem cell phenotype: insights from cancer biology with therapeutic implications for colorectal cancer. PMID: 24787239 Ref: The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of beta-catenin through mechanisms involving FRAT1 and PAK4. PMID: 24829151 Ref: PIK3R3 induces epithelial-to-mesenchymal transition and promotes metastasis in colorectal cancer. PMID: 24837077 Ref: How to explain the contradiction of microRNA 200c expression and survival in solid tumors? A meta-analysis. PMID: 24870778 Ref: [Expressions of STAT3, p-STAT3 and E-cadherin in colorectal cancer and clinical implications]. PMID: 24953370 Ref: [Changes of expression of miR-155 in colitis-associated colonic carcinogenesis]. PMID: 24989910 Ref: STAT3: An Anti-Invasive Factor in Colorectal Cancer? PMID: 24995503 Ref: Arsenite promotes intestinal tumor cell proliferation and invasion by stimulating epithelial-to-mesenchymal transition. PMID: 25010681 Ref: Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients. PMID: 25025961 Ref: Progeny from irradiated colorectal cancer cells acquire an EMT-like phenotype and activate Wnt/beta-catenin pathway. PMID: 25103643 Ref: Rab11 regulates E-cadherin expression and induces cell transformation in colorectal carcinoma. PMID: 25117932 Ref: RNA-seq identifies determinants of oxaliplatin sensitivity in colorectal cancer cell lines. PMID: 25120752 Ref: Overexpression of fibrinogen-like protein 2 induces epithelial-to-mesenchymal transition and promotes tumor progression in colorectal carcinoma. PMID: 25129313 Ref: MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of beta-catenin signaling. PMID: 25193986 Ref: DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition. PMID: 25211188 Ref: Enteric pathogens and cellular transformation: bridging the gaps. PMID: 25216513 Ref: HMGA2 induces transcription factor Slug expression to promote epithelial-to-mesenchymal transition and contributes to colon cancer progression. PMID: 25218351 Ref: Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/beta-catenin signaling pathway. PMID: 25218472 Ref: Epigenetic mechanisms underlying the dynamic expression of cancer-testis genes, PAGE2, -2B and SPANX-B, during mesenchymal-to-epithelial transition. PMID: 25229454 Ref: Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT. PMID: 25238234 Ref: SNAI2 modulates colorectal cancer 5-fluorouracil sensitivity through miR145 repression. PMID: 25249558 Ref: Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut. PMID: 25295490 Ref: Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling. PMID: 25396735 Ref: Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression. PMID: 25499541 Ref: Upregulation of CD147 promotes cell invasion, epithelial-to-mesenchymal transition and activates MAPK/ERK signaling pathway in colorectal cancer. PMID: 25550778 |
Ref: IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction. PMID: 24632618 Ref: Bisphenol A modulates colorectal cancer protein profile and promotes the metastasis via induction of epithelial to mesenchymal transitions. PMID: 25119493 Ref: Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. PMID: 25123959 Ref: Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression. PMID: 25153376 Ref: Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway. PMID: 25305448 Ref: A strategic approach to identification of selective inhibitors of cancer stem cells. PMID: 25325978 Ref: Long non-coding RNA HOTAIR is associated with human cervical cancer progression. PMID: 25405331 Ref: Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway. PMID: 25431258 Ref: FGF8 promotes colorectal cancer growth and metastasis by activating YAP1. PMID: 25473897 Ref: Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis. PMID: 25500541 Ref: High-mobility group box 1: a novel inducer of the epithelial-mesenchymal transition in colorectal carcinoma. PMID: 25511739 Ref: STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer. PMID: 25531324 Ref: Chemokine (C-C Motif) Ligand 5 is Involved in Tumor-Associated Dendritic Cell-Mediated Colon Cancer Progression Through Non-Coding RNA MALAT-1. PMID: 25546229 Ref: Sorcin Enhances Metastasis and Promotes Epithelial-to-Mesenchymal Transition of Colorectal Cancer. PMID: 25567655 Ref: BRD4 inhibitor inhibits colorectal cancer growth and metastasis. PMID: 25603177 Ref: Overexpression of Tbx3 is correlated with Epithelial-Mesenchymal Transition phenotype and predicts poor prognosis of colorectal cancer. PMID: 25628943 Ref: Corrigendum. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. PMID: 25729853 Ref: Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK. PMID: 25730880 Ref: Transcriptional mimicry by tumor-associated stroma. PMID: 25814306 Ref: The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer. PMID: 25868860 Ref: The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon. PMID: 25879211 Ref: Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-beta1/Smads signaling pathway mediated Snail/E-cadherin expression. PMID: 25884904 Ref: BDE-99 (2,2',4,4',5-pentabromodiphenyl ether) triggers epithelial-mesenchymal transition in colorectal cancer cells via PI3K/Akt/Snail signaling pathway. PMID: 25908029 Ref: Notch-1 promotes stemness and epithelial to mesenchymal transition in colorectal cancer. PMID: 25914224 Ref: Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-beta/Smad2/3 signaling. PMID: 25934251 Ref: Short hairpin RNA- mediated gene knockdown of FOXM1 inhibits the proliferation and metastasis of human colon cancer cells through reversal of epithelial-to-mesenchymal transformation. PMID: 25935853 Ref: Overexpression of SIX1 is an independent prognostic marker in stage I-III colorectal cancer. PMID: 25951369 Ref: Epithelial-mesenchymal, mesenchymal-epithelial, and endothelial-mesenchymal transitions in malignant tumors: An update. PMID: 25984514 Ref: AP4 activates cell migration and EMT mediated by p53 in MDA-MB-231 breast carcinoma cells. PMID: 26037074 Ref: Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model. PMID: 26060426 Ref: Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance. PMID: 26064266 Ref: Epithelial-mesenchymal transition in colorectal cancer metastasis: A system review. PMID: 26092594 Ref: Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury. PMID: 26130065 Ref: Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells. PMID: 26136074 Ref: Acquisition of 5-fluorouracil resistance induces epithelial-mesenchymal transitions through the Hedgehog signaling pathway in HCT-8 colon cancer cells. PMID: 26137127 Ref: Octamer transcription factor 1 mediates epithelial-mesenchymal transition in colorectal cancer. PMID: 26178483 Ref: B7H1 Expression and Epithelial-To-Mesenchymal Transition Phenotypes on Colorectal Cancer Stem-Like Cells. PMID: 26284927 Ref: Hsa-miR-19a is associated with lymph metastasis and mediates the TNF-alpha induced epithelial-to-mesenchymal transition in colorectal cancer. PMID: 26302825 Ref: Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelialtomesenchymal transition in colon and breast cancers. PMID: 26318034 Ref: KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. PMID: 26320172 Ref: Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancer. PMID: 26379394 Ref: OCT4B1 promotes cell growth, migration and invasion suppressing sensitivity to omicronxaliplatin in colon cancer. PMID: 26398480 Ref: P-cadherin and the journey to cancer metastasis. PMID: 26438065 Ref: Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3beta pathway in human colon cancer. PMID: 26452029 Ref: Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. PMID: 26495412 Ref: Activin and TGFbeta use diverging mitogenic signaling in advanced colon cancer. PMID: 26497569 Ref: MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation. PMID: 26553592 Ref: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. PMID: 26590805 Ref: microRNA-20a enhances the epithelial-to-mesenchymal transition of colorectal cancer cells by modulating matrix metalloproteinases. PMID: 26622375 Ref: Microenvironmental interactions and expression of molecular markers associated with epithelial-to-mesenchymal transition in colorectal carcinoma. PMID: 26823743 Ref: BCL9/9L-beta-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer. PMID: 26844272 |
Ref: Hepatocyte nuclear factor 4alpha suppresses the aggravation of colon carcinoma. PMID: 25808746 Ref: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases. PMID: 26031752 Ref: Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers. PMID: 26228733 Ref: Gene expression profile in the activation of subperitoneal fibroblasts reflects prognosis of patients with colon cancer. PMID: 26370611 Ref: A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome. PMID: 26446941 Ref: SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. PMID: 26455323 Ref: LncRNA-ATB mediated E-cadherin repression promotes the progression of colon cancer and predicts poor prognosis. PMID: 26487301 Ref: DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53. PMID: 26494468 Ref: An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer. PMID: 26540342 Ref: Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer. PMID: 26603055 Ref: The proline-rich region of glyceraldehyde-3-phosphate dehydrogenase from human sperm may bind SH3 domains, as revealed by a bioinformatic study of low-complexity protein segments. PMID: 26660717 Ref: SphK1 promotes tumor cell migration and invasion in colorectal cancer. PMID: 26662312 Ref: Activation of IRE1alpha-XBP1 pathway induces cell proliferation and invasion in colorectal carcinoma. PMID: 26742428 Ref: Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells. PMID: 26752044 Ref: Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer. PMID: 26754532 Ref: Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer. PMID: 26824987 Ref: Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells. PMID: 26830472 Ref: Norcantharidin Suppresses Colon Cancer Cell Epithelial-Mesenchymal Transition by Inhibiting the alphavbeta6-ERK-Ets1 Signaling Pathway. PMID: 26846153 Ref: LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1alpha activation. PMID: 26856989 Ref: Intraperitoneal (188)Re-Liposome delivery switches ovarian cancer metabolism from glycolysis to oxidative phosphorylation and effectively controls ovarian tumour growth in mice. PMID: 26915312 Ref: The TGF-beta pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells. PMID: 26956045 Ref: Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cancer cells. PMID: 26968633 Ref: Role of cancer stem cells in racial disparity in colorectal cancer. PMID: 26990997 Ref: Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion. PMID: 26996663 Ref: Lysyl Oxidase (LOX) Transcriptionally Regulates SNAI2 Expression and TIMP4 Secretion in Human Cancers. PMID: 27029493 Ref: Overexpression of long non-coding RNA-CTD903 inhibits colorectal cancer invasion and migration by repressing Wnt/beta-catenin signaling and predicts favorable prognosis. PMID: 27035092 Ref: Epigenetic silencing of miR-490-3p promotes development of an aggressive colorectal cancer phenotype through activation of the Wnt/beta-catenin signaling pathway. PMID: 27037061 Ref: High expression of Rab3D predicts poor prognosis and associates with tumor progression in colorectal cancer. PMID: 27046094 Ref: MiR-363-3p inhibits the epithelial-to-mesenchymal transition and suppresses metastasis in colorectal cancer by targeting Sox4. PMID: 27084453 Ref: Systematic study of novel lncRNAs in different gastrointestinal cancer cells. PMID: 27115166 Ref: CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition. PMID: 27149649 Ref: Multifunctional DDX3: dual roles in various cancer development and its related signaling pathways. PMID: 27186411 Ref: beta-III tubulin modulates the behavior of Snail overexpressed during the epithelial-to-mesenchymal transition in colon cancer cells. PMID: 27188792 Ref: Oncogene FOXK1 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition. PMID: 27223064 Ref: Aspirin, platelets, and cancer: The point of view of the internist. PMID: 27344083 Ref: Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation. PMID: 27369075 Ref: Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma. PMID: 27401611 Ref: Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway. PMID: 27421138 Ref: Microwave-assisted synthesis, anti-inflammatory and anti-proliferative activities of new maslinic acid derivatives bearing 1,5- and 1,4-disubstituted triazoles. PMID: 27435116 Ref: Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin-based chemotherapy. PMID: 27446431 Ref: Knockdown of PFTAIRE Protein Kinase 1 (PFTK1) Inhibits Proliferation, Invasion, and EMT in Colon Cancer Cells. PMID: 27458094 Ref: Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ss-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1. PMID: 27463018 Ref: B-cell translocation gene 3 overexpression inhibits proliferation and invasion of colorectal cancer SW480 cells via Wnt/beta-catenin signaling pathway. PMID: 27468874 Ref: Thrombomodulin Influences the Survival of Patients with Non-Metastatic Colorectal Cancer through Epithelial-To-Mesenchymal Transition (EMT). PMID: 27512995 Ref: Decreased expression of LncRNA SLC25A25-AS1 promotes proliferation, chemoresistance, and EMT in colorectal cancer cells. PMID: 27553025 Ref: Systematic review of the old and new concepts in the epithelial-mesenchymal transition of colorectal cancer. PMID: 27570416 Ref: Interplay Between Transcription Factors and MicroRNAs Regulating Epithelial-Mesenchymal Transitions in Colorectal Cancer. PMID: 27573895 Ref: Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer. PMID: 27580057 Ref: The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer. PMID: 27650539 Ref: Efficacy of Cotargeting Angiopoietin-2 and the VEGF Pathway in the Adjuvant Postsurgical Setting for Early Breast, Colorectal, and Renal Cancers. PMID: 27651308 Ref: COUP-TFII suppresses colorectal carcinoma resistance to doxorubicin involving inhibition of epithelial-mesenchymal transition. PMID: 27725871 Ref: Molecular features of doxorubicin-resistance development in colorectal cancer CX-1 cell line. PMID: 27746118 Ref: DcR3 induces epithelial-mesenchymal transition through activation of the TGF-beta3/SMAD signaling pathway in CRC. PMID: 27764793 Ref: Yi Ai Fang, a traditional Chinese herbal formula, impacts the vasculogenic mimicry formation of human colorectal cancer through HIF-1alpha and epithelial mesenchymal transition. PMID: 27806701 Ref: Dual specificity phosphatase 5 is a novel prognostic indicator for patients with advanced colorectal cancer. PMID: 27822421 Ref: KY1022, a small molecule destabilizing Ras via targeting the Wnt/beta-catenin pathway, inhibits development of metastatic colorectal cancer. PMID: 27835580 Ref: Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer. PMID: 27840154 Ref: Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling. PMID: 27863385 Ref: FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer. PMID: 27892920 Ref: Measurement of red blood cell eicosapentaenoic acid (EPA) levels in a randomised trial of EPA in patients with colorectal cancer liver metastases. PMID: 27914515 Ref: Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway. PMID: 28281964 |
Ref: BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression. PMID: 27354468 Ref: Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. PMID: 27375020 Ref: The high expression of long non-coding RNA PANDAR indicates a poor prognosis for colorectal cancer and promotes metastasis by EMT pathway. PMID: 27629879 Ref: The Role of EphA4 Signaling in Radiation-Induced EMT-Like Phenotype in Colorectal Cancer Cells. PMID: 27632701 Ref: Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching. PMID: 27884016 Ref: Possible Molecular Mechanisms by which Vitamin D Prevents Inflammatory Bowel Disease and Colitis-associated Colorectal Cancer. PMID: 27915990 Ref: Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration. PMID: 28049506 Ref: HINT2 downregulation promotes colorectal carcinoma migration and metastasis. PMID: 28088787 Ref: Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis. PMID: 28130225 Ref: miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT. PMID: 28161537 Ref: The expression of cancer stem cell markers in human colorectal carcinoma cells in a microenvironment dependent manner. PMID: 28174005 Ref: Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer. PMID: 28177885 Ref: JianPi JieDu Recipe Inhibits Epithelial-to-Mesenchymal Transition in Colorectal Cancer through TGF-beta/Smad Mediated Snail/E-Cadherin Expression. PMID: 28299321 Ref: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer. PMID: 28341962 Ref: The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells. PMID: 28346422 Ref: TGFbeta engages MEK/ERK to differentially regulate benign and malignant pancreas cell function. PMID: 28368414 Ref: Bidirectional KCNQ1:beta-catenin interaction drives colorectal cancer cell differentiation. PMID: 28373572 Ref: Quantitative evaluation and reversion analysis of the attractor landscapes of an intracellular regulatory network for colorectal cancer. PMID: 28381275 Ref: Luteolin inhibits colorectal cancer cell epithelial-to-mesenchymal transition by suppressing CREB1 expression revealed by comparative proteomics study. PMID: 28391045 Ref: Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levels. PMID: 28420432 Ref: Peroxiredoxin 5 promotes the epithelial-mesenchymal transition in colon cancer. PMID: 28431931 Ref: Effects of Scutellaria barbata polysaccharide on the proliferation, apoptosis and EMT of human colon cancer HT29 Cells. PMID: 28433181 Ref: Antagonistic Effects of p53 and HIF1A on microRNA-34a Regulation of PPP1R11 and STAT3 and Hypoxia-induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells. PMID: 28435028 Ref: C14orf28 downregulated by miR-519d contributes to oncogenicity and regulates apoptosis and EMT in colorectal cancer. PMID: 28455792 Ref: Upregulation of circadian gene 'hClock' contribution to metastasis of colorectal cancer. PMID: 28498393 Ref: Curcumin loading potentiates the chemotherapeutic efficacy of selenium nanoparticles in HCT116 cells and Ehrlich's ascites carcinoma bearing mice. PMID: 28499854 Ref: EMT circulating tumor cells detected by cell-surface vimentin are associated with prostate cancer progression. 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