Primary Site >> Colorectal Cancer

Gene >> ITGB4

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Ref: Integrin Beta-4 expression in colorectal-cancer.
PMID: 21559615
Ref: Activated Rac1 selectively up-regulates the expression of integrin alpha6beta4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells.
PMID: 10585277
Ref: Expression of a highly conserved protein, p27BBP, during the progression of human colorectal cancer.
PMID: 10676626
Ref: Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin beta4.
PMID: 15387376
Ref: Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling.
PMID: 16241905
Ref: Gene profile analysis of colorectal cancer cell lines by cDNA macroarray.
PMID: 17390045
Ref: Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets.
PMID: 18940803
Ref: Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4.
PMID: 19151752
Ref: MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway.
PMID: 20372795
Ref: Association of polymorphisms in microRNA-binding sites and colorectal cancer in an Iranian population.
PMID: 22939228
Ref: Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITGBeta4-PDCD4) as predictor of metastatic tumor potential.
PMID: 24149370
Ref: Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer.
PMID: 25360999
Ref: MYC Regulates alpha6 Integrin Subunit Expression and Splicing Under Its Pro-Proliferative ITGA6A Form in Colorectal Cancer Cells.
PMID: 29401653